hERG channel function: beyond long QT (Q27008078)

Min Li

series ordinal

2

1 reference

language of work or name

1 reference

March 2013

1 reference

Acta Pharmacologica Sinica

1 March 2013

8 references

22 March 2019

3 April 2019

17 June 2019

28 November 2019

15 December 2019

23 November 2020

8 February 2021

31 July 2022

9 references

22 March 2019

3 April 2019

17 June 2019

28 November 2019

15 December 2019

23 November 2020

8 February 2021

31 July 2022

34

1 reference

issue

3

1 reference

page(s)

329-35

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

copyright license

8 references

22 March 2019

3 April 2019

17 June 2019

28 November 2019

15 December 2019

23 November 2020

8 February 2021

on focus list of Wikimedia project

31 July 2022

ScienceSource

0 references

cites work

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Novel roles for hERG K(+) channels in cell proliferation and apoptosis

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A family of potassium channel genes related to eag in Drosophila and mammals

21 March 2017

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 March 2017

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The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line

21 March 2017

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Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade

21 March 2017

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Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current

21 March 2017

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Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle

21 March 2017

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21 March 2017

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Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels

7 April 2017

1 reference

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Functional characterization of ether-à-go-go-related gene potassium channels in midbrain dopamine neurons - implications for a role in depolarization block

28 September 2017

1 reference

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Human ether-a-go-go-related gene K+ channels regulate shedding of leukemia cell-derived microvesicles

28 September 2017

1 reference

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Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells

28 September 2017

1 reference

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Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: I. Experimental analysis of the use-dependent block

28 September 2017

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Functional integrative levels in the human interactome recapitulate organ organization

28 September 2017

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Altered gene expression by low-dose arsenic exposure in humans and cultured cardiomyocytes: assessment by real-time PCR arrays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

The role of inflammation in epilepsy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Systems pharmacology of arrhythmias

28 September 2017

1 reference

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The contribution of Kv7 channels to pregnant mouse and human myometrial contractility

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Effects of ranolazine, a novel anti-anginal drug, on ion currents and membrane potential in pituitary tumor GH(3) cells and NG108-15 neuronal cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Rapid kinetic interactions of ranolazine with HERG K+ current

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

How many human genes can be defined as housekeeping with current expression data?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

HERG K+ channel expression in CD34+/CD38-/CD123(high) cells and primary leukemia cells and analysis of its regulation in leukemia cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Clinical practice. Long-QT syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Erg K+ channels modulate contractile activity in the bovine epididymal duct

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Expression and significance of HERG protein in gastric cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Electrical activity in early neuronal development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Microarray analysis of mercury-induced changes in gene expression in human liver carcinoma (HepG2) cells: importance in immune responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Merg1a K+ channel induces skeletal muscle atrophy by activating the ubiquitin proteasome pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

hERG potassium channels and cardiac arrhythmia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

A voltage-driven switch for ion-independent signaling by ether-à-go-go K+ channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Molecular diversity and regulation of renal potassium channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Selective expression of HERG and Kv2 channels influences proliferation of uterine cancer cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Teratogenicity by the hERG potassium channel blocking drug almokalant: use of hypoxia marker gives evidence for a hypoxia-related mechanism mediated via embryonic arrhythmia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

HERG K(+) currents in human prolactin-secreting adenoma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Functional up-regulation of HERG K+ channels in neoplastic hematopoietic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Neuronal KCNQ potassium channels: physiology and role in disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

HERG K+ channels activation during beta(1) integrin-mediated adhesion to fibronectin induces an up-regulation of alpha(v)beta(3) integrin in the preosteoclastic leukemia cell line FLG 29.1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Mechanism of block and identification of the verapamil binding domain to HERG potassium channels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

HERG-like K+ channels in microglia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

A HERG-like K+ channel in rat F-11 DRG cell line: pharmacological identification and biophysical characterization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Potassium channels, proliferation and G1 progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Characterization of Erg K+ channels in alpha- and beta-cells of mouse and human islets

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Neurogenetic analysis of potassium currents in Drosophila: synergistic effects on neuromuscular transmission in double mutants.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Tissue and species distribution of mRNA for the IKr-like K+ channel, erg.

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Posttranslational modulation of glucocorticoid feedback inhibition at the pituitary level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Characterisation of a cell swelling-activated K+-selective conductance of ehrlich mouse ascites tumour cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Imatinib has the potential to exert its antileukemia effects by down-regulating hERG1 K+ channels in chronic myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Expression and function of KCNH2 (HERG) in the human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Expression and activity of potassium ion channels in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Role of hERG1 K(+) channels in leukemia cells as a positive regulator in SDF-1a-induced proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Regulation of the voltage-insensitive step of HERG activation by extracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Erg K+ currents modulate excitability in mouse mitral/tufted neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Functional roles of an ERG current isolated in cerebellar Purkinje neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

Differential effects of blockade of ERG channels on gamma oscillations and excitability in rat hippocampal slices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2013.6

ERG K+ channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

herg encodes a K+ current highly conserved in tumors of different histogenesis: a selective advantage for cancer cells?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587915

Expression and immunolocalization of ERG1 potassium channels in the rat kidney

28 November 2018

1 reference

12 December 2020

The differential antibacterial and gastrointestinal effects of erythromycin and its chiral isolates

1 reference

12 December 2020

Differential expression of potassium ion channels in human renal cell carcinoma

1 reference

12 December 2020

HERG K+ channel, a regulator of tumor cell apoptosis and proliferation

1 reference

12 December 2020

Downregulation of the HERG (KCNH2) K(+) channel by ceramide: evidence for ubiquitin-mediated lysosomal degradation

1 reference

12 December 2020

Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release

1 reference

12 December 2020

Acceleration of sperm transit time and reduction of sperm reserves in the epididymis of rats exposed to sibutramine

1 reference

12 December 2020

Is erythromycin therapy teratogenic in humans?

1 reference

12 December 2020

ERG conductance expression modulates the excitability of ventral horn GABAergic interneurons that control rhythmic oscillations in the developing mouse spinal cord

1 reference

12 December 2020

Berberine inhibits SDF-1-induced AML cells and leukemic stem cells migration via regulation of SDF-1 level in bone marrow stromal cells

1 reference

12 December 2020