Integrated PK-PD and agent-based modeling in oncology (Q27006577)

Joseph D. Butner

series ordinal

2

1 reference

language of work or name

1 reference

April 2015

1 reference

Journal of Pharmacokinetics and Pharmacodynamics

published in

1 reference

volume

42

1 reference

issue

2

1 reference

page(s)

179-89

1 reference

https://scigraph.springernature.com/pub.10.1007/s10928-015-9403-7

exact match

0 references

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Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin

28 September 2017

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Clinically driven design of multi-scale cancer models: the ContraCancrum project paradigm.

28 September 2017

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Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical response

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Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression

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Multiscale cancer modeling

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Computational modeling of tumor response to vascular-targeting therapies--part I: validation

28 September 2017

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FEM-based 3-D tumor growth prediction for kidney tumor

28 September 2017

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The pharmacokinetic/pharmacodynamic pipeline: translating anticancer drug pharmacology to the clinic

28 September 2017

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Identifying therapeutic targets in a combined EGFR-TGFβR signalling cascade using a multiscale agent-based cancer model

28 September 2017

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Hybrid models of tumor growth.

28 September 2017

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Nonlinear modelling of cancer: bridging the gap between cells and tumours

28 September 2017

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A theoretical quantitative model for evolution of cancer chemotherapy resistance

28 September 2017

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Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis

28 September 2017

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Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model

28 September 2017

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28 September 2017

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Migration rules: tumours are conglomerates of self-metastases.

28 September 2017

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Modeling of tumor growth and anticancer effects of combination therapy

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28 September 2017

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Evolution of cell motility in an individual-based model of tumour growth.

28 September 2017

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Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation

28 September 2017

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Three-dimensional multispecies nonlinear tumor growth--I Model and numerical method

28 September 2017

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Cross-scale sensitivity analysis of a non-small cell lung cancer model: linking molecular signaling properties to cellular behavior

28 September 2017

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Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing regimens in EGFR wild-type and mutant tumor models

28 September 2017

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Immunological aspects of cancer chemotherapy

28 September 2017

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The role of mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modelling in translational research of biologics

28 September 2017

1 reference

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Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

28 September 2017

1 reference

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Bioreductive drugs: from concept to clinic

28 September 2017

1 reference

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An evolutionary hybrid cellular automaton model of solid tumour growth

28 September 2017

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From in vivo to in silico biology and back

28 September 2017

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Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling

28 September 2017

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Transport of molecules in the tumor interstitium: a review

28 September 2017

1 reference

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Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors

28 September 2017

1 reference

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Unified hypothesis for the origin of aplastic anemia and periodic hematopoiesis

28 September 2017

1 reference

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The effect of interstitial pressure on therapeutic agent transport: coupling with the tumor blood and lymphatic vascular systems

28 September 2017

1 reference

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The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems

31 May 2018

1 reference

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Models of collective cell behaviour with crowding effects: comparing lattice-based and lattice-free approaches.

31 May 2018

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Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA.

31 May 2018

1 reference

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The biological effectiveness of targeted radionuclide therapy based on a whole-body pharmacokinetic model

31 May 2018

1 reference

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Using adaptive model predictive control to customize maintenance therapy chemotherapeutic dosing for childhood acute lymphoblastic leukemia

31 May 2018

1 reference

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Simulating Brain Tumor Heterogeneity with a Multiscale Agent-Based Model: Linking Molecular Signatures, Phenotypes and Expansion Rate

31 May 2018

1 reference

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Simulating non-small cell lung cancer with a multiscale agent-based model

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985529

A Gompertzian model of human breast cancer growth.

31 May 2018

1 reference

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Predicting the course of Gompertzian growth

31 May 2018

1 reference

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A model for the chemotherapy of acute leukemia with 1-beta-D-arabinofuranosylcytosine

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985529

Individual-based and continuum models of growing cell populations: a comparison.

31 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Continuous and discrete mathematical models of tumor-induced angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Testing additivity of anticancer agents in pre-clinical studies: a PK/PD modelling approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Metabolic changes during carcinogenesis: potential impact on invasiveness.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Tumour resistance to cisplatin: a modelling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Growth of a virtual tumour using probabilistic methods of cell generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Hybrid Model of Erythropoiesis and Leukemia Treatment with Cytosine Arabinoside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

A multiscale mechanobiological modelling framework using agent-based models and finite element analysis: application to vascular tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Lattice-free descriptions of collective motion with crowding and adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Simulating the hallmarks of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Agent-based Simulation Platforms: Review and Development Recommendations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Modeling tumor response after combined administration of different immune-stimulatory agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

An implementation of the Expectation-Maximisation (EM) algorithm for population pharmacokinetic-pharmacodynamic modelling in ACSLXTREME.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

A hybrid cellular automaton model of solid tumor growth and bioreductive drug transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

A novel, patient-specific mathematical pathology approach for assessment of surgical volume: application to ductal carcinoma in situ of the breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Incorporation of gemcitabine and cytarabine into DNA by DNA polymerase beta and ligase III/XRCC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Modeling the effects of vasculature evolution on early brain tumor growth.

21 January 2018

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A change of strategy in the war on cancer.

21 January 2018

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Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Graphics processing units accelerated semiclassical initial value representation molecular dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Implementation and evaluation of various demons deformable image registration algorithms on a GPU.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leu

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

21 January 2018

Discrete cell modeling

1 reference

https://api.crossref.org/works/10.1007%2FS10928-015-9403-7

Analysis of events associated with cell cycle arrest at G2 phase and cell death induced by cisplatin

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25588379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A cellular automaton model for tumour growth in inhomogeneous environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25588379

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Paradoxical dependencies of tumor dormancy and progression on basic cell kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25588379