Understanding dendritic cells and their role in cutaneous carcinoma and cancer immunotherapy (Q27004702)

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23 December 2020

Understanding dendritic cells and their role in cutaneous carcinoma and cancer immunotherapy (English)

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19 September 2019

23 December 2020

2 references

12 October 2019

1 November 2020

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21 October 2019

adoptive immunotherapy

1 reference

1 August 2020

1 reference

4

1 reference

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29 February 2020

author name string

Hiroshi Mitsui

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2

2 references

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29 February 2020

Diane Felsen

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3

2 references

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29 February 2020

Valerie R Yanofsky

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1

1 reference

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language of work or name

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28 March 2013

13 references

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20 June 2019

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25 June 2019

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21 October 2019

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29 February 2020

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Clinical and Developmental Immunology

14 references

12 March 2019

3 April 2019

20 June 2019

17 June 2019

25 June 2019

19 September 2019

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21 March 2017

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21 March 2017

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

21 March 2017

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7 April 2017

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

7 April 2017

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CD200 upregulation in vascular endothelium surrounding cutaneous squamous cell carcinoma.

7 April 2017

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Optimizing dendritic cell-based immunotherapy: tackling the complexity of different arms of the immune system

28 September 2017

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Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells

28 September 2017

1 reference

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Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

28 September 2017

1 reference

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The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming

28 September 2017

1 reference

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The contact sensitizer diphenylcyclopropenone has adjuvant properties in mice and potential application in epicutaneous immunotherapy

28 September 2017

1 reference

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Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

28 September 2017

1 reference

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Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Peptide-loaded Langerhans cells, despite increased IL15 secretion and T-cell activation in vitro, elicit antitumor T-cell responses comparable to peptide-loaded monocyte-derived dendritic cells in vivo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Tumor-associated macrophages in the cutaneous SCC microenvironment are heterogeneously activated

28 September 2017

1 reference

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Harnessing dendritic cells in inflammatory skin diseases.

28 September 2017

1 reference

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The contribution of Langerhans cells to cutaneous malignancy

28 September 2017

1 reference

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The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C.

28 September 2017

1 reference

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Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma

28 September 2017

1 reference

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Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

28 September 2017

1 reference

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Langerhans cells as targets for immunotherapy against skin cancer.

28 September 2017

1 reference

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Building on dendritic cell subsets to improve cancer vaccines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Harnessing human dendritic cell subsets for medicine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Harnessing human dendritic cell subsets to design novel vaccines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Resident and "inflammatory" dendritic cells in human skin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

CD8+ T cell efficacy in vaccination and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Central role of dendritic cells in the regulation and deregulation of immune responses.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Interferon-alpha induces TRAIL expression and cell death via an IRF-1-dependent mechanism in human bladder cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

IL-15-induced human DC efficiently prime melanoma-specific naive CD8+ T cells to differentiate into CTL.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Topical immunotherapy with diphenylcyclopropenone in the treatment of chronic extensive alopecia areata

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Cutaneous dendritic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Cell biology of antigen processing in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Dendritic cell immunotherapy: mapping the way.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Langerhans cells - dendritic cells of the epidermis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

How dendritic cells and microbes interact to elicit or subvert protective immune responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

The use of diphenylcyclopropenone in the treatment of recalcitrant warts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Cross-presentation, dendritic cells, tolerance and immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Dendritic cells in cancer immunotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Dendritic cells generated either from CD34+ progenitor cells or from monocytes differ in their ability to activate antigen-specific CD8+ T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Langerhans cells from human cutaneous squamous cell carcinoma induce strong type 1 immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Disease-independent skin recruitment and activation of plasmacytoid predendritic cells following imiquimod treatment.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Activity of human contact allergens in the murine local lymph node assay

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Activation of human dendritic cells through CD40 cross-linking.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Two distinct types of Langerhans cells populate the skin during steady state and inflammation

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Tumor-associated macrophages press the angiogenic switch in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Stromal CD10 expression, as well as increased dermal macrophages and decreased Langerhans cells, are associated with malignant transformation of keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Solar-simulated ultraviolet radiation induces abnormal maturation and defective chemotaxis of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Antigen crosspresentation by human plasmacytoid dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

A model system using tape stripping for characterization of Langerhans cell-precursors in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Tumor immunotherapy by epicutaneous immunization requires langerhans cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Induction of therapeutically relevant cytotoxic T lymphocytes in humans by percutaneous peptide immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Cutting edge: priming of CTL by transcutaneous peptide immunization with imiquimod

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Immunization onto bare skin with synthetic peptides: immunomodulation with a CpG-containing oligodeoxynucleotide and effective priming of influenza virus-specific CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Topical diphencyprone immunotherapy for cutaneous metastatic melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

The number and distribution of blood dendritic cells in the epidermis and dermis of healthy human subjects.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor alpha: II. Functional analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3625554

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

28 November 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F624123

Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation

21 January 2018

1 reference

12 December 2020

Progressor but not regressor skin tumours inhibit Langerhans' cell migration from epidermis to local lymph nodes

1 reference

12 December 2020

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

1 reference

12 December 2020

The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells

1 reference

12 December 2020

Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine

1 reference

12 December 2020

Cutting edge: CD1a+ antigen-presenting cells in human dermis respond rapidly to CCR7 ligands

1 reference

12 December 2020

TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses

1 reference

12 December 2020

Langerhans cells in squamous cell carcinoma vs. pseudoepitheliomatous hyperplasia of the skin

1 reference

12 December 2020

Dermal-resident CD14+ cells differentiate into Langerhans cells

1 reference

12 December 2020

Immunosuppression affects CD4+ mRNA expression and induces Th2 dominance in the microenvironment of cutaneous squamous cell carcinoma in organ transplant recipients

1 reference

12 December 2020

Dendritic cells in cancer immunotherapy

1 reference

12 December 2020

Mature Human Langerhans Cells Derived from CD34+ Hematopoietic Progenitors Stimulate Greater Cytolytic T Lymphocyte Activity in the Absence of Bioactive IL-12p70, by Either Single Peptide Presentation or Cross-Priming, Than Do Dermal-Interstitial or

1 reference

12 December 2020

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets

1 reference

12 December 2020

Induction of tolerance by IL-10-treated dendritic cells

1 reference

12 December 2020

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

1 reference

12 December 2020

Identifiers

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606870%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606870%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606870%20AND%20SRC:MED&resulttype=core&format=json