Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder (Q27002419)

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English	Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder	scientific article

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scholarly article

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25 February 2020

Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder (English)

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25 February 2020

bipolar disorder

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inferred from title

1

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25 February 2020

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Dawn F Ionescu

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25 February 2020

Carlos A Zarate Jr

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Carlos A Zarate

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25 February 2020

Erica M Richards

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Erica M Richards

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25 February 2020

author name string

Daniel C Mathews

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11 March 2013

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25 February 2020

C N S Spectrums

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25 February 2020

18

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25 February 2020

5

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25 February 2020

242-251

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Europe PubMed Central

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25 February 2020

The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Lithium facilitates apoptotic signaling induced by activation of the Fas death domain-containing receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

A molecular mechanism for the effect of lithium on development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Pramipexole for bipolar II depression: a placebo-controlled proof of concept study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Reduced Brain Inositol in Lithium-treated Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Inhibitory effects of anticonvulsant drugs on cyclic nucleotide accumulation in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

SMIT1 haploinsufficiency causes brain inositol deficiency without affecting lithium-sensitive behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

NFAT/Fas signaling mediates the neuronal apoptosis and motor side effects of GSK-3 inhibition in a mouse model of lithium therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Chronic treatment with mood stabilizers increases membrane GRK3 in rat frontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

21 March 2017

Nutrient-based therapies for bipolar disorder: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Genetic association of cyclic AMP signaling genes with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Selective G2/M arrest in a p53(Val135)-transformed cell line induced by lithium is mediated through an intricate network of MAPK and β-catenin signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Homeostatic functions of BCL-2 proteins beyond apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

The role of p38 MAPK in valproic acid induced microglia apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Glutamate receptors as targets of protein kinase C in the pathophysiology and treatment of animal models of mania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Protein kinase C inhibition in the treatment of mania: a double-blind, placebo-controlled trial of tamoxifen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Reduced CREB phosphorylation after chronic lithium treatment is associated with down-regulation of CaM kinase IV in rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Protein kinase A activity in platelets from patients with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Altered IMPA2 gene expression and calcium homeostasis in bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

The high affinity inositol transport system--implications for the pathophysiology and treatment of bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Signaling: cellular insights into the pathophysiology of bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Abnormal G protein alpha(s) - and alpha(i2)-subunit mRNA expression in bipolar affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 September 2017

Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

A pilot study of hormone modulation as a new treatment for mania in women with bipolar affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Chronic carbamazepine treatment increases myristoylated alanine-rich C kinase substrate phosphorylation in the rat cerebral cortex via down-regulation of calcineurin A alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Increased cyclic AMP-dependent protein kinase activity in postmortem brain from patients with bipolar affective disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Increased membrane-associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Enhanced protein kinase C activity and translocation in bipolar affective disorder brains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Postmortem cerebral cortex Gs alpha-subunit levels are elevated in bipolar affective disorder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Carbamazepine distinguishes between adenosine receptors that mediate different second messenger responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Hyperfunctional G proteins in mononuclear leukocytes of patients with mania.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

31 May 2018

Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Phosphorylation status of glucocorticoid receptor, heat shock protein 70, cytochrome c and Bax in lymphocytes of euthymic, depressed and manic bipolar patients

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Microarray analysis of rat brain gene expression after chronic administration of sodium valproate

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Biphasic changes in the Ser-9 phosphorylation of glycogen synthase kinase-3beta after electroconvulsive shock in the rat brain

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Sodium-myo-inositol co-transporter (SMIT-1) mRNA is increased in neutrophils of patients with bipolar 1 disorder and down-regulated under treatment with mood stabilizers

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Protein kinase C inhibition by tamoxifen antagonizes manic-like behavior in rats: implications for the development of novel therapeutics for bipolar disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

The cAMP-dependent protein kinase A and brain-derived neurotrophic factor expression in lymphoblast cells of bipolar affective disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Altered cAMP-dependent protein kinase subunit immunolabeling in post-mortem brain from patients with bipolar affective disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1092852913000138

21 January 2018

Association of the iPLA2β gene with bipolar disorder and assessment of its interaction with TRPM2 gene polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 November 2018

TRPM2 variants and bipolar disorder risk: confirmation in a family-based association study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 November 2018

Receptor-mediated activation of G proteins is increased in postmortem brains of bipolar affective disorder subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 November 2018

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3936782

28 November 2018

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of carbamazepine on cyclic nucleotides in CSF of patients with affective illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C and phospholipase C activity and expression of their specific isozymes is decreased and expression of MARCKS is increased in platelets of bipolar but not in unipolar patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel evidence of different mechanisms of lithium and valproate neuroprotective action on human SY5Y neuroblastoma cells: caspase-3 dependency

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mononuclear leukocyte levels of G proteins in depressed patients with bipolar disorder or major depressive disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated platelet membrane phosphatidylinositol-4,5-bisphosphate in bipolar mania

1 reference

https://pubmed.ncbi.nlm.nih.gov/23472710

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1017/S1092852913000138

2 references

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23472710%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2 references

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23472710%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2 references

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23472710%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

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