Carotenoid metabolism in mammals, including man: formation, occurrence, and function of apocarotenoids (Q27001195)

Crossref

E. H. Harrison

series ordinal

2

1 reference

Crossref

language of work or name

1 reference

July 2013

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Journal of Lipid Research

published in

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volume

54

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issue

7

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page(s)

1719-30

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The retinoid X receptors and their ligands

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Retinal biosynthesis in fungi: characterization of the carotenoid oxygenase CarX from Fusarium fujikuroi

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Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 March 2017

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Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter

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Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium

21 March 2017

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Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A

21 March 2017

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Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity

21 March 2017

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A human retinoic acid receptor which belongs to the family of nuclear receptors

21 March 2017

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A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor

21 March 2017

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Structural basis for isotype selectivity of the human retinoic acid nuclear receptor

21 March 2017

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A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A

21 March 2017

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21 March 2017

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Overview of nomenclature of nuclear receptors

21 March 2017

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Expression pattern and localization of beta,beta-carotene 15,15'-dioxygenase in different tissues

21 March 2017

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Stimulation of gap junctional communication: comparison of acyclo-retinoic acid and lycopene

21 March 2017

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Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists

21 March 2017

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Identification of a receptor for the morphogen retinoic acid

21 March 2017

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Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression

21 March 2017

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Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

21 March 2017

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Cloning and expression of beta,beta-carotene 15,15'-dioxygenase

21 March 2017

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A decade of molecular biology of retinoic acid receptors

21 March 2017

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Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

7 April 2017

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The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

7 April 2017

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Enzymology of retinoic acid biosynthesis and degradation

7 April 2017

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Retinol and retinyl esters: biochemistry and physiology

28 September 2017

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Vitamin A and retinoid signaling: genomic and nongenomic effects

28 September 2017

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Naturally occurring eccentric cleavage products of provitamin A β-carotene function as antagonists of retinoic acid receptors

28 September 2017

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Apo-10'-lycopenoic acid, a lycopene metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice.

28 September 2017

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Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids

28 September 2017

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Physiological insights into all-trans-retinoic acid biosynthesis

28 September 2017

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Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis

28 September 2017

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Modulation of RXR function through ligand design

28 September 2017

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Key enzymes of the retinoid (visual) cycle in vertebrate retina

28 September 2017

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Carotene and novel apocarotenoid concentrations in orange-fleshed Cucumis melo melons: determinations of β-carotene bioaccessibility and bioavailability

28 September 2017

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Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and β-cryptoxanthin by ferret carotene-9',10'-monooxygenase.

28 September 2017

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Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoid

28 September 2017

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Colors with functions: elucidating the biochemical and molecular basis of carotenoid metabolism

28 September 2017

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Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma

28 September 2017

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C/EBPalpha regulates SIRT1 expression during adipogenesis

28 September 2017

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ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679377

Sirtuins regulate key aspects of lipid metabolism

28 September 2017

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Function of retinoic acid receptors during embryonic development

28 September 2017

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Are the health attributes of lycopene related to its antioxidant function?

28 September 2017

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Carotenoid metabolism: biosynthesis, regulation, and beyond

28 September 2017

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Strigolactone inhibition of shoot branching

28 September 2017

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Inhibition of shoot branching by new terpenoid plant hormones

28 September 2017

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The biochemical basis for structural diversity in the carotenoids of chlorophototrophic bacteria

28 September 2017

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Biosynthesis and regulation of carotenoids in Dunaliella: progresses and prospects

28 September 2017

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The molecular basis of retinoid absorption: a genetic dissection

28 September 2017

1 reference

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Carotenoids and carotenogenesis in cyanobacteria: unique ketocarotenoids and carotenoid glycosides

28 September 2017

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Apo-10'-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo.

28 September 2017

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Rhizosphere communication of plants, parasitic plants and AM fungi

28 September 2017

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Lycopenoids: are lycopene metabolites bioactive?

28 September 2017

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The biochemical characterization of ferret carotene-9',10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo

28 September 2017

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Retinoid x receptor heterodimers in the metabolic syndrome

28 September 2017

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Induction of PXR-mediated metabolism by beta-carotene

28 September 2017

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Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol.

28 September 2017

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Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803.

28 September 2017

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Carotenoids normally present in serum inhibit proliferation and induce differentiation of a human monocyte/macrophage cell line (U937).

28 September 2017

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The nuclear pregnane X receptor regulates xenobiotic detoxification

28 September 2017

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Cancer chemoprevention drug targets

28 September 2017

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Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids

28 September 2017

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Carotenoids and retinoids as suppressors on adipocyte differentiation via nuclear receptors

28 September 2017

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Retinoid X receptor and its partners in the nuclear receptor family

28 September 2017

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Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

28 September 2017

1 reference

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Epigenetic toxicology as toxicant-induced changes in intracellular signalling leading to altered gap junctional intercellular communication

28 September 2017

1 reference

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Specific oxidative cleavage of carotenoids by VP14 of maize

28 September 2017

1 reference

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Synthesis and biological activities of higher homologues of retinoic acid.

28 September 2017

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Induction of HL-60 cell differentiation by carotenoids

28 September 2017

1 reference

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Retinoic acid biosynthesis and metabolism

28 September 2017

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Beta-carotene, carotenoids, and disease prevention in humans.

28 September 2017

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Absorption, metabolism, and transport of carotenoids.

28 September 2017

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Cellular transport and metabolism of vitamin A: roles of the cellular retinoid-binding proteins.

28 September 2017

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Transport and metabolism of vitamin A.

28 September 2017

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Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid

28 September 2017

1 reference

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Vitamin A and carotene in animal nutrition.

28 September 2017

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The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine

28 September 2017

1 reference

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Carotenoid vitamin A precursors and analogs in foods and feeds

28 September 2017

1 reference

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Induction of differentiation of human promyelocytic leukemia cell line HL-60 by retinoyl glucuronide, a biologically active metabolite of vitamin A

28 September 2017

1 reference

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Evidence for a lecithin-retinol acyltransferase activity in the rat small intestine

28 September 2017

1 reference

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Provitamin A function of carotenoids: the conversion of beta-carotene into vitamin A.

28 September 2017

1 reference

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The intracellular vitamin A-binding proteins: an overview of their functions

28 September 2017

1 reference

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Studies evaluating antioxidants and beta-carotene as chemopreventives

28 September 2017

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Vitamin A metabolism: new perspectives on absorption, transport, and storage

28 September 2017

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Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

28 September 2017

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Studies on the metabolism of β-carotene and apo-β-carotenoids in rats and chickens

28 September 2017

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Biological activity of (all-E)-beta-apo-12'-carotenoic acid and the geometrical isomers on human acute promyelocytic leukemia cell line HL-60.

28 September 2017

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The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα.

28 September 2017

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Asymmetric cleavage of beta-carotene yields a transcriptional repressor of retinoid X receptor and peroxisome proliferator-activated receptor responses

31 May 2018

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Vitamin A and carotene: The absence of the liver oil vitamin A from carotene. VI. The conversion of carotene to vitamin A in vivo

31 May 2018

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Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase

31 May 2018

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Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists

31 May 2018

1 reference

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Characterization of products formed during the autoxidation of beta-carotene

31 May 2018

1 reference

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Studies on the relative biopotencies and intestinal absorption of different apo-beta-carotenoids in rats and chickens

31 May 2018

1 reference

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Rat plasma prealbumin. Metabolic studies on effects of vitamin A status and on tissue distribution

31 May 2018

1 reference

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Apo-10'-lycopenoic acid impacts adipose tissue biology via the retinoic acid receptors

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3679377

Mechanisms of provitamin A (carotenoid) and vitamin A (retinol) transport into and out of intestinal Caco-2 cells.

28 November 2018

1 reference

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Excentral cleavage of beta-carotene in vivo in a healthy man.

28 November 2018

1 reference

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A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

28 November 2018

1 reference

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Carotenoids and their metabolites are naturally occurring activators of gene expression via the pregnane X receptor

28 November 2018

1 reference

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Beta-carotene and beta-apo-14'-carotenoic acid prevent the reduction of retinoic acid receptor beta in benzo[a]pyrene-treated normal human bronchial epithelial cells.

28 November 2018

1 reference

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Excentric cleavage products of beta-carotene inhibit estrogen receptor positive and negative breast tumor cell growth in vitro and inhibit activator protein-1-mediated transcriptional activation

28 November 2018

1 reference

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Acyclo-retinoic acid induces apoptosis in human prostate cancer cells

28 November 2018

1 reference

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Effects of acyclo-retinoic acid and lycopene on activation of the retinoic acid receptor and proliferation of mammary cancer cells.

28 November 2018

1 reference

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The Reaction Mechanism of the Enzyme-Catalyzed Central Cleavage of beta-Carotene to Retinal This research was supported by F. Hoffmann-La Roche AG and the Swiss National Science Foundation. We are grateful to F. Hoffmann-La Roche AG for a generous g

28 November 2018

1 reference

12 December 2020

Lycopene absorption in human intestinal cells and in mice involves scavenger receptor class B type I but not Niemann-Pick C1-like 1

1 reference

12 December 2020

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

1 reference

12 December 2020

VITAMIN A AND CAROTENOIDS. I. INTESTINAL ABSORPTION AND METABOLISM OF 14C-LABELLED VITAMIN A ALCOHOL AND BETA-CAROTENE IN THE RAT

1 reference

12 December 2020

Reduction of retinaldehyde bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine

1 reference

12 December 2020

Enzymatic formation of 9-cis, 13-cis, and all-trans retinals from isomers of beta-carotene

1 reference

12 December 2020

BIOSYNTHESIS OF VITAMIN A WITH RAT INTESTINAL ENZYMES

1 reference

12 December 2020

Beta-oxidation in rabbit liver in vitro and in the perfused ferret liver contributes to retinoic acid biosynthesis from beta-apocarotenoic acids

1 reference

12 December 2020

Lecithin:retinol acyltransferase and retinyl ester hydrolase activities are differentially regulated by retinoids and have distinct distributions between hepatocyte and nonparenchymal cell fractions of rat liver

1 reference

12 December 2020

CMO1 deficiency abolishes vitamin A production from beta-carotene and alters lipid metabolism in mice

1 reference

12 December 2020

Dietary beta-carotene absorption and metabolism in ferrets and rats

1 reference

12 December 2020

In vitro measurement of beta-carotene cleavage activity: methodological considerations and the effect of other carotenoids on beta-carotene cleavage

1 reference

12 December 2020

beta-Carotene-15,15'-dioxygenase (EC 1.13.11.21) isolation reaction mechanism and an improved assay procedure

1 reference

12 December 2020

Distributions of carotenoids and alpha-tocopherol among lipoproteins do not change when human plasma is incubated in vitro

1 reference

12 December 2020

Apo-8'-lycopenal and apo-12'-lycopenal are metabolic products of lycopene in rat liver

1 reference

12 December 2020

Enzymatic conversion of beta-carotene into beta-apo-carotenals and retinoids by human, monkey, ferret, and rat tissues

1 reference

12 December 2020

beta-carotene is converted primarily to retinoids in rats in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.R039537

1 reference

release_kgmymxxjsrcilo7pc4uzpbh4yu

123498

Fatcat ID

0 references

123498

1 reference

1 reference

1 reference