Role of amino acid transporters in amino acid sensing (Q26999339)

Crossref

language of work or name

1 reference

January 2014

1 reference

American Journal of Clinical Nutrition

published in

1 reference

volume

99

1 reference

issue

1

1 reference

page(s)

223S-230S

1 reference

Nutrient regulation of the mTOR complex 1 signaling pathway

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Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

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LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis

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Amino acids and mTORC1: from lysosomes to disease

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Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

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Leucine and mTORC1: a complex relationship

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Regulation of TOR by small GTPases

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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 March 2017

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Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway

21 March 2017

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Dietary Guidelines should reflect new understandings about adult protein needs

21 March 2017

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Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 (SNAT2) System A transporter gene

21 March 2017

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Identification and characterization of a lysosomal transporter for small neutral amino acids

21 March 2017

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Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism

21 March 2017

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Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy

21 March 2017

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Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter

21 March 2017

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21 March 2017

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Interorgan amino acid transport and its regulation

21 March 2017

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CATs and HATs: the SLC7 family of amino acid transporters

21 March 2017

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The brain's response to an essential amino acid-deficient diet and the circuitous route to a better meal

21 March 2017

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Identification of SLC38A7 (SNAT7) protein as a glutamine transporter expressed in neurons

21 March 2017

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Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2)

21 March 2017

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The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway

21 March 2017

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 March 2017

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Bidirectional transport of amino acids regulates mTOR and autophagy

7 April 2017

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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

7 April 2017

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Evolutionary origin of amino acid transporter families SLC32, SLC36 and SLC38 and physiological, pathological and therapeutic aspects

28 September 2017

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An extended proteome map of the lysosomal membrane reveals novel potential transporters

28 September 2017

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The role of amino acid transporters in nutrition.

28 September 2017

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The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb

28 September 2017

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HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5.

28 September 2017

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Exercise and amino acid anabolic cell signaling and the regulation of skeletal muscle mass

28 September 2017

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Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes

28 September 2017

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Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo

28 September 2017

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AMPK and mTOR in cellular energy homeostasis and drug targets

28 September 2017

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Insulin resistance and the metabolism of branched-chain amino acids in humans

28 September 2017

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p62 is a key regulator of nutrient sensing in the mTORC1 pathway.

28 September 2017

1 reference

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Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats

28 September 2017

1 reference

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From transporter to transceptor: signaling from transporters provokes re-evaluation of complex trafficking and regulatory controls: endocytic internalization and intracellular trafficking of nutrient transceptors may, at least in part, be governed b

28 September 2017

1 reference

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Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse

28 September 2017

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SNAT2 transceptor signalling via mTOR: a role in cell growth and proliferation?

28 September 2017

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The role of amino acid transporters in inherited and acquired diseases.

28 September 2017

1 reference

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Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase

28 September 2017

1 reference

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Control of translation initiation through integration of signals generated by hormones, nutrients, and exercise

28 September 2017

1 reference

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Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation

28 September 2017

1 reference

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An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

28 September 2017

1 reference

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PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

28 September 2017

1 reference

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Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

28 September 2017

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RalA functions as an indispensable signal mediator for the nutrient-sensing system

28 September 2017

1 reference

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Amino acid regulation of TOR complex 1.

28 September 2017

1 reference

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Amino acid transport across mammalian intestinal and renal epithelia

28 September 2017

1 reference

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Brasilicardin A, a natural immunosuppressant, targets amino Acid transport system L.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic initiation factor 2alpha phosphorylation and cap-independent translation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

System B0,+ amino acid transport regulates the penetration stage of blastocyst implantation with possible long-term developmental consequences through adulthood.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime?

28 September 2017

1 reference

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Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Role of amino acid transport and countertransport in nutrition and metabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

The transport systems of mammalian lysosomes

28 September 2017

1 reference

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The competitive advantage of a dual-transporter system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Separate and shared lysosomal transport of branched and aromatic dipolar amino acids

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Characterization of lysosomal monoiodotyrosine transport in rat thyroid cells. Evidence for transport by system h.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Glutaminolysis activates Rag-mTORC1 signaling.

28 November 2018

1 reference

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Glutamine stimulates mTORC1 independent of the cell content of essential amino acids.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.

28 November 2018

1 reference

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L-type amino acid transporter 1 inhibitors inhibit tumor cell growth

28 November 2018

1 reference

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Tertiary active transport of amino acids reconstituted by coexpression of System A and L transporters in Xenopus oocytes.

28 November 2018

1 reference

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Regulation of placental amino acid transporter activity by mammalian target of rapamycin

28 November 2018

1 reference

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Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3862456

Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284439

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3945/AJCN.113.070086

1 reference

1 reference

1 reference

PubMed publication ID

24284439

1 reference