Newly discovered angiogenesis inhibitors and their mechanisms of action (Q26998498)

Jian-ming Feng

series ordinal

2

1 reference

Jian Ding

series ordinal

3

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language of work or name

1 reference

September 2012

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Acta Pharmacologica Sinica

published in

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volume

33

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issue

9

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page(s)

1103-11

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Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

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Modes of resistance to anti-angiogenic therapy

21 March 2017

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 March 2017

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Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 March 2017

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AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.

21 March 2017

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Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms

28 September 2017

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Acquired resistance to drugs targeting receptor tyrosine kinases

28 September 2017

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Multihistology, target-driven pilot trial of oral topotecan as an inhibitor of hypoxia-inducible factor-1α in advanced solid tumors

28 September 2017

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Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer

28 September 2017

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Pseudolaric acids: isolation, bioactivity and synthetic studies.

28 September 2017

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c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner

28 September 2017

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BB, a new EGFR inhibitor, exhibits prominent anti-angiogenesis and antitumor activities

28 September 2017

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Marine-derived oligosaccharide sulfate (JG3) suppresses heparanase-driven cell adhesion events in heparanase over-expressing CHO-K1 cells

28 September 2017

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MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition.

28 September 2017

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Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomas

28 September 2017

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Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent

28 September 2017

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FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

28 September 2017

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The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo

28 September 2017

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Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) through inhibiting protein synthesis

28 September 2017

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28 September 2017

Biology of HIF-1alpha

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Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicine and a structure-activity relationship study

28 September 2017

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MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison

28 September 2017

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Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR.

28 September 2017

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Angiogenesis in cancer: molecular mechanisms, clinical impact

28 September 2017

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Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116

Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells

28 September 2017

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TKI-31 inhibits angiogenesis by combined suppression signaling pathway of VEGFR2 and PDGFRbeta

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116

The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116

Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.

28 September 2017

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In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects

28 September 2017

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Transcription factor c-Jun activation represses mdr-1 gene expression.

28 September 2017

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Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells

28 September 2017

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Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116

Antiangiogenic potential of 10-hydroxycamptothecin

28 September 2017

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Anti-angiogenic effects of Shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis

28 September 2017

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The scientific contributions of M. Judah Folkman to cancer research.

31 May 2018

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Antiangiogenic activity of 11,11'-dideoxyverticillin, a natural product isolated from the fungus Shiraia bambusicola.

21 January 2018

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Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.97

Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model.

21 January 2018

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https://api.crossref.org/works/10.1038%2FAPS.2012.97

Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin.

21 January 2018

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https://api.crossref.org/works/10.1038%2FAPS.2012.97

E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models

21 January 2018

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https://api.crossref.org/works/10.1038%2FAPS.2012.97

Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22922347