Biomaterial delivery of morphogens to mimic the natural healing cascade in bone (Q26996479)

2

object named as

Katharina Schmidt-Bleek

0 references

author name string

Manav Mehta

1

1 reference

Crossref

Georg N. Duda

3

1 reference

Crossref

David J. Mooney

4

1 reference

Crossref

language of work or name

1 reference

September 2012

1 reference

Advanced Drug Delivery Reviews

published in

1 reference

volume

64

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issue

12

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page(s)

1257-76

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Imaging in the era of molecular oncology

cites work

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Growth factor interactions in bone regeneration

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Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones.

28 September 2017

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28 September 2017

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Optical advances in skeletal imaging applied to bone metastases.

28 September 2017

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Fracture healing is accelerated in the absence of the adaptive immune system.

28 September 2017

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Mechanical stimulation of the pro-angiogenic capacity of human fracture haematoma: involvement of VEGF mechano-regulation

28 September 2017

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28 September 2017

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The early fracture hematoma and its potential role in fracture healing

28 September 2017

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Mesenchymal stem cells expressing osteogenic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect.

28 September 2017

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Simple strategy for bone regeneration with a BMP-2/7 gene expression cassette vector

28 September 2017

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Cyclic strain disrupts endothelial network formation on Matrigel.

28 September 2017

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28 September 2017

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Spatiotemporal delivery strategies for promoting musculoskeletal tissue regeneration

28 September 2017

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In vitro cellular responses to scaffolds containing two microencapulated growth factors

28 September 2017

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Marrow fat and the bone microenvironment: developmental, functional, and pathological implications

28 September 2017

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28 September 2017

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Role of hypoxia inducible factor-1 alpha pathway in bone regeneration.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

28 September 2017

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Growth factors in bone repair

28 September 2017

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Characterization of a rat osteotomy model with impaired healing

28 September 2017

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Fracture vascularity and bone healing: a systematic review of the role of VEGF.

28 September 2017

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28 September 2017

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28 September 2017

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A perspective: engineering periosteum for structural bone graft healing.

28 September 2017

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New materials for tissue engineering: towards greater control over the biological response

28 September 2017

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Functions of RANKL/RANK/OPG in bone modeling and remodeling

28 September 2017

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Cell delivery mechanisms for tissue repair

28 September 2017

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Nonunions and the potential of stem cells in fracture-healing

28 September 2017

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Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Applications of gene therapy and adult stem cells in bone bioengineering.

28 September 2017

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Hydrogels in controlled release formulations: network design and mathematical modeling

28 September 2017

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Ultrasound-induced cavitation: applications in drug and gene delivery

28 September 2017

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Virus-based gene therapy strategies for bone regeneration.

28 September 2017

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Bone tissue engineering by gene delivery

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VEGF scaffolds enhance angiogenesis and bone regeneration in irradiated osseous defects

28 September 2017

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Synthetic multivalent ligands as probes of signal transduction

28 September 2017

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Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion

28 September 2017

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28 September 2017

Bone graft substitutes

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Allograft and alloplastic bone substitutes: a review of science and technology for the craniomaxillofacial surgeon

28 September 2017

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Massive allograft use in orthopedic oncology.

28 September 2017

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Gene delivery from polymer scaffolds for tissue engineering

28 September 2017

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Cell-specific targeting of nanoparticles by multivalent attachment of small molecules

28 September 2017

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Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection

28 September 2017

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Hypoxia inducible factor (HIF) in rheumatology: low O2! See what HIF can do!

28 September 2017

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Biomaterial microarrays: rapid, microscale screening of polymer-cell interaction.

28 September 2017

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Modeling of drug release from polymeric delivery systems--a review

28 September 2017

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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering.

28 September 2017

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"Programmed polymeric devices" for pulsed drug delivery.

28 September 2017

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Accelerated bone repair with the use of a synthetic BMP-2-derived peptide and bone-marrow stromal cells.

28 September 2017

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Gene therapy progress and prospects: electroporation and other physical methods.

28 September 2017

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Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases.

28 September 2017

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Death in the third dimension: apoptosis regulation and tissue architecture

28 September 2017

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Nonunion: general principles and experimental data

28 September 2017

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Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies.

28 September 2017

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Management of posttraumatic segmental bone defects

28 September 2017

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Analyzing bone, blood vessels, and biomaterials with microcomputed tomography

28 September 2017

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In vitro effects of combined and sequential delivery of two bone growth factors

28 September 2017

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Polymeric growth factor delivery strategies for tissue engineering

28 September 2017

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Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

28 September 2017

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Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4.

28 September 2017

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Bone graft substitutes: past, present, future

28 September 2017

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Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis

28 September 2017

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Bone morphogenetic protein-2 application by a poly(D,L-lactide)-coated interbody cage: in vivo results of a new carrier for growth factors.

28 September 2017

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Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover

28 September 2017

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The role of growth factors in the repair of bone. Biology and clinical applications.

28 September 2017

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Bone tissue engineering: hope vs hype

28 September 2017

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Cell-interactive alginate hydrogels for bone tissue engineering

28 September 2017

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Porous tricalcium phosphate and transforming growth factor used for anterior spine surgery

28 September 2017

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Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Responsive polymeric delivery systems.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Tissue engineering via local gene delivery: update and future prospects for enhancing the technology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

In vivo nonviral delivery factors to enhance bone repair.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Is human fracture hematoma inherently angiogenic?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Potential applications and delivery strategies for bone morphogenetic proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Sustained release emphasizing recombinant human bone morphogenetic protein-2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Growth factors regulate expression of osteoblast-associated genes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Biosynthetic bone grafting

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

DNA delivery from polymer matrices for tissue engineering

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Insulinlike growth factor 1- and 2-augmented collagen gel repair of facial osseous defects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Alginate hydrogels as synthetic extracellular matrix materials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Polymer concepts in tissue engineering

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Complete regeneration of bone in the baboon by recombinant human osteogenic protein-1 (hOP-1, bone morphogenetic protein-7).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Stimulation of new bone formation by direct transfer of osteogenic plasmid genes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Protein-free cell culture on an artificial substrate with covalently immobilized insulin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone morphogenetic protein-2: biology and applications.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Present and future applications of biomaterials in controlled drug delivery systems

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Repair of segmental defects of the tibia with cancellous bone grafts augmented with human bone morphogenetic protein. A preliminary report

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Pros, cons, and costs of INFUSE in spinal surgery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Comparison of the vascularity of fasciocutaneous tissue and muscle for coverage of open tibial fractures

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Differentiation of osteoblasts in three-dimensional culture in processed cancellous bone matrix: quantitative analysis of gene expression based on real-time reverse transcription-polymerase chain reaction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Non-viral gene delivery regulated by stiffness of cell adhesion substrates.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone morphogenetic protein-2 decorated silk fibroin films induce osteogenic differentiation of human bone marrow stromal cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Biological activity of rhBMP-2 released from PLGA microspheres

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Novel formulation of fibroblast growth factor-2 in a hyaluronan gel accelerates fracture healing in nonhuman primates

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

The engineering of biomaterials exhibiting recognition and specificity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

A determinant of bone architecture. The minimum effective strain.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Covalent functionalization of TiO2 nanotube arrays with EGF and BMP-2 for modified behavior towards mesenchymal stem cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Inflammatory phase of bone healing initiates the regenerative healing cascade.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Hypoxic regulation of mesenchymal stem cell migration: the role of RhoA and HIF-1α.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Tissue models: a living system on a chip.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Synergistic enhancement of human bone marrow stromal cell proliferation and osteogenic differentiation on BMP-2-derived and RGD peptide concentration gradients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

A 5-mm femoral defect in female but not in male rats leads to a reproducible atrophic non-union.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Standard bone healing stages occur during delayed bone healing, albeit with a different temporal onset and spatial distribution of callus tissues.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Near-infrared fluorescent probe traces bisphosphonate delivery and retention in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Time-programmed dual release formulation by multilayered drug-loaded nanofiber meshes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Validation of β-Actin Used as Endogenous Control for Gene Expression Analysis in Mechanobiology studies: Amendments

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Insight into the molecular pathophysiology of delayed bone healing in a sheep model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Sequential BMP-2/BMP-7 delivery from polyester nanocapsules

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Incorporation of a sequential BMP-2/BMP-7 delivery system into chitosan-based scaffolds for bone tissue engineering

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Differential regulation of blood vessel formation between standard and delayed bone healing.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Stromal cell-derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Peptide immobilized on gold particles enhances cell growth

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Mechanical characterization of external fixator stiffness for a rat femoral fracture model

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

A preliminary report on the effect of dimeric rhGDF-5 and its monomeric form rhGDF-5C465A on bone healing of rat cranial defects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Mechanical induction of critically delayed bone healing in sheep: radiological and biomechanical results.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Sequential growth factor delivery from complexed microspheres for bone tissue engineering

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Effect of cell-based VEGF gene therapy on healing of a segmental bone defect

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Early dynamization by reduced fixation stiffness does not improve fracture healing in a rat femoral osteotomy model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Optimal delivery systems for bone morphogenetic proteins in orthopedic applications should model initial tissue repair structures by using a heparin-incorporated fibrin-fibronectin matrix.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Reconstruction of tibia defects by ipsilateral vascularized fibula transposition.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Ultrasound-based nonviral gene delivery induces bone formation in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Integrated approach to designing growth factor delivery systems.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: a combined computational and experimental approach.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Timely fracture-healing requires optimization of axial fixation stability.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

The sequential expression profiles of growth factors from osteoprogenitors [correction of osteroprogenitors] to osteoblasts in vitro

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly(L-lactic-co-glycolic acid) scaffold.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Tethered epidermal growth factor provides a survival advantage to mesenchymal stem cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Endochondral ossification in vitro is influenced by mechanical bending.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Temporally regulated delivery of VEGF in vitro and in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Nucleofection-based ex vivo nonviral gene delivery to human stem cells as a platform for tissue regeneration

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone regeneration by modified gene-activated matrix: effectiveness in segmental tibial defects in rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Recombinant human growth/differentiation factor-5 (rhGDF-5) induced bone formation in murine calvariae

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Instability prolongs the chondral phase during bone healing in sheep.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Combined angiogenic and osteogenic factor delivery enhances bone marrow stromal cell-driven bone regeneration.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Novel modulation of drug delivery using binary zinc-alginate-pectinate polyspheres for zero-order kinetics over several days: experimental design strategy to elucidate the crosslinking mechanism

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Surgical approach influences periprosthetic femoral bone density

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Mathematical modeling and optimization of drug delivery from intratumorally injected microspheres.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Long-term effects of local growth factor (IGF-I and TGF-beta 1) treatment on fracture healing. A safety study for using growth factors.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Synergistic effect of IGF-I and TGF-beta1 on fracture healing in rats: single versus combined application of IGF-I and TGF-beta1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Regulating bone formation via controlled scaffold degradation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Localized insulin-like growth factor I delivery to enhance new bone formation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Influences of vascularization and osteogenic cells on heterotopic bone formation within a madreporic ceramic in rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Repair of bone defects using synthetic mimetics of collagenous extracellular matrices

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Bone morphogenetic protein-2 coating of titanium implants increases biomechanical strength and accelerates bone remodeling in fracture treatment: a biomechanical and histological study in rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Experimental studies on bone induction using low-molecular-weight poly (DL-lactide-co-glycolide) as a carrier for recombinant human bone morphogenetic protein-2.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Insulin-like growth factor-1 and transforming growth factor-beta1 accelerates osteotomy healing using polylactide-coated implants as a delivery system: a biomechanical and histological study in minipigs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

TGF-beta1 release from biodegradable polymer microparticles: its effects on marrow stromal osteoblast function.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Platelet-derived growth factor/insulin-like growth factor-1 combination and bone regeneration around implants placed into extraction sockets: a histometric study in dogs.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Tissue engineers build new bone

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Engineering of an FGF-proteoglycan fusion protein with heparin-independent, mitogenic activity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Segmental bone repair by tissue-engineered periosteal cell transplants with bioresorbable fleece and fibrin scaffolds in rabbits

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Combination of bone marrow and TGF-beta1 augment the healing of critical-sized bone defects.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Induction of new bone by ceramic bovine bone with recombinant human bone morphogenetic protein 2 and transforming growth factor beta.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

Recombinant transforming growth factor-beta1 induces endochondral bone in the baboon and synergizes with recombinant osteogenic protein-1 (bone morphogenetic protein-7) to initiate rapid bone formation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

ESB Research Award 1996. Biophysical stimuli on cells during tissue differentiation at implant interfaces.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

The effects of insulin-like growth factor-1 on critical-size calvarial defects in Sprague-Dawley rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425736

The bone regenerative effect of platelet-derived growth factor-BB delivered with a chitosan/tricalcium phosphate sponge carrier

28 November 2018

1 reference

12 December 2020

Mechanobiology of skeletal regeneration

1 reference

12 December 2020

Bone formation on apatite-coated titanium with incorporated BMP-2/heparin in vivo

1 reference

12 December 2020

The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study

1 reference

12 December 2020

Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2

1 reference

12 December 2020

Immobilization and bioactivity evaluation of FGF-1 and FGF-2 on powdered silicon-doped hydroxyapatite and their scaffolds for bone tissue engineering

1 reference

12 December 2020

Osteopromotion for cranioplasty: an experimental study in rats using acidic fibroblast growth factor

1 reference

12 December 2020

In reference to Acute airway obstruction in cervical spinal procedures with bone morphogenetic proteins

1 reference

12 December 2020

Promoted bone healing at a rabbit skull gap between autologous bone fragment and the surrounding intact bone with biodegradable microspheres containing transforming growth factor-beta1

1 reference

12 December 2020

Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing

1 reference

12 December 2020

[Mechanical modification of callus healing]

1 reference

12 December 2020

Effect of platelet-derived growth factor on tibial osteotomies in rabbits

1 reference

12 December 2020

Microfluidics enables small-scale tissue-based drug metabolism studies with scarce human tissue

1 reference

12 December 2020

Carrier systems for bone morphogenetic proteins

1 reference

12 December 2020

Effectable application of vascular endothelial growth factor to critical sized rat calvaria defects

1 reference

12 December 2020

Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model

1 reference

12 December 2020

Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold

1 reference

12 December 2020

Angiogenic effects of sequential release of VEGF-A165 and PDGF-BB with alginate hydrogels after myocardial infarction

1 reference

12 December 2020

Acute airway obstruction in cervical spinal procedures with bone morphogenetic proteins

1 reference

12 December 2020

Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing

1 reference

12 December 2020

The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities

1 reference

12 December 2020

CDMP-2 induces bone or tendon-like tissue depending on mechanical stimulation

1 reference

12 December 2020

Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration

1 reference

12 December 2020

Application of rhBMP-7 and platelet-rich plasma in the treatment of long bone non-unions

1 reference

12 December 2020

Surface immobilization of bone morphogenetic protein 2 via a self-assembled monolayer formation induces cell differentiation

1 reference

12 December 2020

A bone regeneration study: transforming growth factor-beta 1 and its delivery

1 reference

12 December 2020

Combination of growth factors inhibits bone ingrowth in the bone harvest chamber

1 reference

12 December 2020

The effect of osteogenin (a bone morphogenetic protein) on the formation of bone in orthotopic segmental defects in rats

1 reference

12 December 2020

[Primary and secondary healing of bone fractures]

1 reference

12 December 2020

The effect of exogenous transforming growth factor-beta 2 on healing fractures in the rabbit

1 reference

12 December 2020

Osteoprogenitor cells within skeletal muscle

1 reference

12 December 2020

Repair of large bone defects with the use of autologous bone marrow stromal cells

1 reference

12 December 2020

Polymeric system for dual growth factor delivery

1 reference

12 December 2020

Concepts of fracture union, delayed union, and nonunion

1 reference

12 December 2020

Effect of recombinant human bone morphogenetic protein-2 on fracture healing in a goat tibial fracture model

1 reference

12 December 2020

Alginate hydrogel linked with synthetic oligopeptide derived from BMP-2 allows ectopic osteoinduction in vivo

1 reference

12 December 2020

Controlled growth factor release from synthetic extracellular matrices

1 reference

12 December 2020

Continuous administration of basic fibroblast growth factor (FGF-2) accelerates bone induction on rat calvaria--an application of a new drug delivery system

1 reference

12 December 2020

The cell and molecular biology of fracture healing

1 reference

12 December 2020