Insights into the initiation of type 2 immune responses (Q26865705)

author

Andrew N. J. McKenzie

series ordinal

3

object named as

Andrew N. J. McKenzie

1 reference

Chris J. Oliphant

1

1 reference

Jillian L. Barlow

series ordinal

2

1 reference

language of work or name

1 reference

December 2011

1 reference

1 reference

134

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issue

4

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page(s)

378-85

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Systemically dispersed innate IL-13-expressing cells in type 2 immunity

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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

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IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation

21 March 2017

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Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

21 March 2017

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The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1

21 March 2017

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Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

21 March 2017

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 March 2017

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IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells

21 March 2017

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Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

21 March 2017

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Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract

21 March 2017

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 March 2017

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T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function

21 March 2017

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IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo

21 March 2017

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IL-33, a potent inducer of adaptive immunity to intestinal nematodes

21 March 2017

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Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities

21 March 2017

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Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Genetic analysis of basophil function in vivo.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Identification of constitutively active interleukin 33 (IL-33) splice variant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Critical role of IL-25 in nematode infection-induced alterations in intestinal function.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

IL-33 is a crucial amplifier of innate rather than acquired immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Regulation of IL-9 expression by IL-25 signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Interleukin-33 is biologically active independently of caspase-1 cleavage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

A mechanism for the initiation of allergen-induced T helper type 2 responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Proteases in parasitic diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Interleukin 25 promotes the initiation of proallergic type 2 responses.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Cutting edge: IPSE/alpha-1, a glycoprotein from Schistosoma mansoni eggs, induces IgE-dependent, antigen-independent IL-4 production by murine basophils in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

A role for TSLP in the development of inflammation in an asthma model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

A role for thymic stromal lymphopoietin in CD4(+) T cell development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Localization of a major allergen, Der p 2, in the gut and faecal pellets of Dermatophagoides pteronyssinus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Stat6 regulation of in vivo IL-4 responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

IL-4 directs the development of Th2-like helper effectors

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230792

Enzymatically active papain preferentially induces an allergic response in mice.

31 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Lacto-N-fucopentaose III found on Schistosoma mansoni egg antigens functions as adjuvant for proteins by inducing Th2-type response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

A soluble thymic stromal lymphopoietin (TSLP) antagonist, TSLPR-immunoglobulin, reduces the severity of allergic disease by regulating pulmonary dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Interleukin-25: a cytokine linking eosinophils and adaptive immunity in Churg-Strauss syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Association of IL-17RB gene polymorphism with asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Parasite antigen-driven basophils are a major source of IL-4 in human filarial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2011.03499.X

Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release

21 January 2018

1 reference

12 December 2020

Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma

1 reference

12 December 2020

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

1 reference

12 December 2020

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

1 reference

12 December 2020

Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding

1 reference

12 December 2020