The gut mucosal immune response to Toxoplasma gondii (Q26863747)

E. Y. Denkers

series ordinal

2

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language of work or name

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March 2015

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37

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PubMed

issue

3

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PubMed

page(s)

108-17

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Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger

PubMed

cites work

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Small intestinal inflammation following oral infection with Toxoplasma gondii does not occur exclusively in C57BL/6 mice: review of 70 reports from the literature

21 January 2018

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The role of epithelial cells in immune regulation in the gut.

21 January 2018

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Early response of mucosal epithelial cells during Toxoplasma gondii infection

21 January 2018

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Paneth cells: maestros of the small intestinal crypts

21 January 2018

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Intraepithelial lymphocytes: their shared and divergent immunological behaviors in the small and large intestine

21 January 2018

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The light and dark sides of intestinal intraepithelial lymphocytes

21 January 2018

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Intestinal dendritic cells in the regulation of mucosal immunity

21 January 2018

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Innate lymphoid cells: from border protection to the initiation of inflammatory diseases

21 January 2018

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Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men.

21 January 2018

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Innate immunity to Toxoplasma gondii infection

21 January 2018

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Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells

21 January 2018

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IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.

21 January 2018

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Complex immune cell interplay in the gamma interferon response during Toxoplasma gondii infection

21 January 2018

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Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

21 January 2018

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Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

21 January 2018

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Securing the immune tightrope: mononuclear phagocytes in the intestinal lamina propria

21 January 2018

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Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells

21 January 2018

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ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

21 January 2018

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In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

21 January 2018

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CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites

21 January 2018

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The role of retinoic acid in tolerance and immunity

21 January 2018

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Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha

21 January 2018

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Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.

21 January 2018

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TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite

21 January 2018

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Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses

21 January 2018

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CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection

21 January 2018

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Monocytes mediate mucosal immunity to Toxoplasma gondii

21 January 2018

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Monocyte-mediated defense against microbial pathogens.

21 January 2018

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Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2

21 January 2018

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Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

21 January 2018

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Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes.

21 January 2018

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Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii

21 January 2018

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Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

21 January 2018

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CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection

21 January 2018

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CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation

21 January 2018

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A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice

21 January 2018

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The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

21 January 2018

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21 January 2018

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The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

21 January 2018

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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

21 January 2018

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The IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens

21 January 2018

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Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication

21 January 2018

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IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins

21 January 2018

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Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it

21 January 2018

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CCR5 mediates specific migration of Toxoplasma gondii-primed CD8 lymphocytes to inflammatory intestinal epithelial cells.

21 January 2018

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Oral infection of C57BL/6 mice with Toxoplasma gondii: a new model of inflammatory bowel disease?

21 January 2018

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Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii

21 January 2018

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TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii

21 January 2018

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Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease

21 January 2018

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Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control.

21 January 2018

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Treatment with interleukin-18 binding protein ameliorates Toxoplasma gondii-induced small intestinal pathology that is induced by bone marrow cell-derived interleukin-18.

21 January 2018

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IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

21 January 2018

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Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

21 January 2018

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Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections

21 January 2018

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Interleukin 17 receptor signaling is deleterious during Toxoplasma gondii infection in susceptible BL6 mice.

21 January 2018

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Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection

21 January 2018

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Lamina propria CD4+ T lymphocytes synergize with murine intestinal epithelial cells to enhance proinflammatory response against an intracellular pathogen

21 January 2018

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CCR2-dependent intraepithelial lymphocytes mediate inflammatory gut pathology during Toxoplasma gondii infection

21 January 2018

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Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection

21 January 2018

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Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection.

21 January 2018

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CCR2 receptor is essential to activate microbicidal mechanisms to control Toxoplasma gondii infection in the central nervous system

21 January 2018

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Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice

21 January 2018

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Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

21 January 2018

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Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

21 January 2018

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Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

21 January 2018

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Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

21 January 2018

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T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation

21 January 2018

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Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection

21 January 2018

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The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology

21 January 2018

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Microbial infection-induced expansion of effector T cells overcomes the suppressive effects of regulatory T cells via an IL-2 deprivation mechanism

21 January 2018

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Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

21 January 2018

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Role of Blimp-1 in programing Th effector cells into IL-10 producers

21 January 2018

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Intestinal intraepithelial lymphocytes prevent pathogen-driven inflammation and regulate the Smad/T-bet pathway of lamina propria CD4+ T cells.

21 January 2018

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T cell tolerance and immunity to commensal bacteria.

21 January 2018

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Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells

21 January 2018

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Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli

21 January 2018

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Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii.

21 January 2018

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Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

21 January 2018

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The role of infection in the aetiology of inflammatory bowel disease

21 January 2018

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The treatment-naive microbiome in new-onset Crohn's disease

21 January 2018

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Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

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Targeting TNF-α for the treatment of inflammatory bowel disease

21 January 2018

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The microbiome in inflammatory bowel disease: current status and the future ahead

21 January 2018

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