Human CMV-specific T-cell responses in kidney transplantation; toward changing current risk-stratification paradigm (Q26850340)

main subject

kidney transplantation

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Marc Lúcia

1

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Elena Crespo

2

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Josep M. Cruzado

3

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Josep M. Grinyó

4

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Oriol Bestard

5

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language of work or name

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July 2014

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published in

Transplant International

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volume

27

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issue

7

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page(s)

643-56

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The impact of cytomegalovirus infection and disease on rejection episodes in renal allograft recipients

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Impact of early cytomegalovirus infection and disease on long-term recipient and kidney graft survival

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Asymptomatic cytomegalovirus infection is associated with increased risk of new-onset diabetes mellitus and impaired insulin release after renal transplantation

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Antiviral medications to prevent cytomegalovirus disease and early death in recipients of solid-organ transplants: a systematic review of randomised controlled trials.

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Adoptive T-cell therapy of a lung transplanted patient with severe CMV disease and resistance to antiviral therapy

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Meta-analysis: the efficacy of strategies to prevent organ disease by cytomegalovirus in solid organ transplant recipients

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International consensus guidelines on the management of cytomegalovirus in solid organ transplantation

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Canadian society of transplantation consensus workshop on cytomegalovirus management in solid organ transplantation final report

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Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial

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Valganciclovir prophylaxis versus preemptive therapy in cytomegalovirus-positive renal allograft recipients: 1-year results of a randomized clinical trial

21 January 2018

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Six-month prophylaxis is cost effective in transplant patients at high risk for cytomegalovirus infection

21 January 2018

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Prolonged prophylaxis with valganciclovir is cost effective in reducing posttransplant cytomegalovirus disease within the United States

21 January 2018

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Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients

21 January 2018

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Antiviral drugs for cytomegalovirus in transplant recipients: advantages of preemptive therapy

21 January 2018

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Symptomatic cytomegalovirus infection in seropositive kidney recipients: reinfection with donor virus rather than reactivation of recipient virus

21 January 2018

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Linking CMV serostatus to episodes of CMV reactivation following lung transplantation by measuring CMV-specific CD8+ T-cell immunity

21 January 2018

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Cytomegalovirus replication kinetics in solid organ transplant recipients managed by preemptive therapy

21 January 2018

1 reference

Importance of the cytomegalovirus seropositive recipient as a contributor to disease burden after solid organ transplantation

21 January 2018

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The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients

21 January 2018

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Innate sensing of viruses by toll-like receptors

21 January 2018

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Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

21 January 2018

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Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection

21 January 2018

1 reference

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation

21 January 2018

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Antibodies are not essential for the resolution of primary cytomegalovirus infection but limit dissemination of recurrent virus.

21 January 2018

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Serum antibody response to the gH/gL/pUL128-131 five-protein complex of human cytomegalovirus (HCMV) in primary and reactivated HCMV infections

21 January 2018

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Clinical utility of cytomegalovirus (CMV) serology testing in high-risk CMV D+/R- transplant recipients

21 January 2018

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Impaired direct priming of CD8 T cells by donor-derived cytomegalovirus following kidney transplantation.

21 January 2018

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Properties of CD4(+) T cells in human cytomegalovirus infection

21 January 2018

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Cross-reactive recognition of human and primate cytomegalovirus sequences by human CD4 cytotoxic T lymphocytes specific for glycoprotein B and H.

21 January 2018

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Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation

21 January 2018

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Contemporaneous fluctuations in T cell responses to persistent herpes virus infections

21 January 2018

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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

21 January 2018

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Ex vivo profiling of CD8+-T-cell responses to human cytomegalovirus reveals broad and multispecific reactivities in healthy virus carriers.

21 January 2018

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Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection.

21 January 2018

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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

21 January 2018

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Highly protective in vivo function of cytomegalovirus IE1 epitope-specific memory CD8 T cells purified by T-cell receptor-based cell sorting

21 January 2018

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Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells

21 January 2018

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High levels of CMV-IE-1-specific memory T cells are associated with less alloimmunity and improved renal allograft function.

21 January 2018

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Cytomegalovirus infects human lymphocytes and monocytes: virus expression is restricted to immediate-early gene products

21 January 2018

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State-of-the-art monitoring of cytomegalovirus-specific cell-mediated immunity after organ transplant: a primer for the clinician

21 January 2018

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Strategies for managing cytomegalovirus in transplant recipients

21 January 2018

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Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation.

21 January 2018

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Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study

21 January 2018

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Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication

21 January 2018

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

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Paradoxical aspects of rapamycin immunobiology in transplantation

21 January 2018

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mTOR regulates memory CD8 T-cell differentiation

21 January 2018

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Comparison of cytomegalovirus (CMV) enzyme-linked immunosorbent spot and CMV quantiferon gamma interferon-releasing assays in assessing risk of CMV infection in kidney transplant recipients

21 January 2018

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Cross-validation of IFN-γ Elispot assay for measuring alloreactive memory/effector T cell responses in renal transplant recipients.

21 January 2018

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Standardization and cross validation of alloreactive IFNγ ELISPOT assays within the clinical trials in organ transplantation consortium

21 January 2018

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Levels of virus-specific CD4 T cells correlate with cytomegalovirus control and predict virus-induced disease after renal transplantation

21 January 2018

1 reference

Virologic and immunologic monitoring of cytomegalovirus to guide preemptive therapy in solid-organ transplantation.

21 January 2018

1 reference

Pretransplant interferon-γ secretion by CMV-specific CD8+ T cells informs the risk of CMV replication after transplantation.

21 January 2018

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Pretransplant immediately early-1-specific T cell responses provide protection for CMV infection after kidney transplantation.

21 January 2018

1 reference

Longitudinal assessment of cytomegalovirus (CMV)-specific immune responses in liver transplant recipients at high risk for late CMV disease

21 January 2018

1 reference

Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients.

21 January 2018

1 reference

Primary cytomegalovirus phosphoprotein 65-specific CD8+ T-cell responses and T-bet levels predict immune control during early chronic infection in lung transplant recipients

21 January 2018

1 reference

Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study

21 January 2018

1 reference

Human cytomegalovirus-specific T-cell immune reconstitution in preemptively treated heart transplant recipients identifies subjects at critical risk for infection

21 January 2018

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Monitoring cytomegalovirus T-cell immunity in small bowel/multivisceral transplant recipients

21 January 2018

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Quantiferon-CMV test in prediction of cytomegalovirus infection after kidney transplantation.

21 January 2018

1 reference

Cytomegalovirus-specific T-cell responses and viral replication in kidney transplant recipients

21 January 2018

1 reference

A prospective longitudinal analysis of cytomegalovirus (CMV)-specific CD4+ and CD8+ T cells in kidney allograft recipients at risk of CMV infection

21 January 2018

1 reference

Dominance of virus-specific CD8 T cells in human primary cytomegalovirus infection

21 January 2018

1 reference

Functional impairment of cytomegalovirus specific CD8 T cells predicts high-level replication after renal transplantation

21 January 2018

1 reference

Cellular immune responses to cytomegalovirus in renal transplant recipients

21 January 2018

1 reference

Association Between Mannose-Binding Lectin Deficiency and Cytomegalovirus Infection After Kidney Transplantation

21 January 2018

1 reference

Investigation of promoter variations in dendritic cell-specific ICAM3-grabbing non-integrin (DC-SIGN) (CD209) and their relevance for human cytomegalovirus reactivation and disease after allogeneic stem-cell transplantation

21 January 2018

1 reference

Clinical Utility of Cytomegalovirus Cell-Mediated Immunity in Transplant Recipients With Cytomegalovirus Viremia

21 January 2018

1 reference

Natural killer cell responses in renal transplant patients with cytomegalovirus infection

21 January 2018

1 reference

7 January 2021

Cytotoxic t cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients

1 reference

7 January 2021

Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor

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7 January 2021

Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation

1 reference

7 January 2021

Evaluation of Cytomegalovirus (CMV)–Specific T Cell Immune Reconstitution Revealed That Baseline Antiviral Immunity, Prophylaxis, or Preemptive Therapy but not Antithymocyte Globulin Treatment Contribute to CMV‐Specific T Cell Reconstitution in K

1 reference

7 January 2021

Bidirectional transmission of infectious cytomegalovirus between monocytes and vascular endothelial cells: an in vitro model

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7 January 2021

Antiviral antibody responses and intrauterine transmission after primary maternal cytomegalovirus infection

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7 January 2021

Blood cyclosporine concentrations and cytomegalovirus infection following heart transplantation

1 reference

7 January 2021

CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study

1 reference

7 January 2021

Differences in CMV-Specific T-Cell Levels and Long-Term Susceptibility to CMV Infection after Kidney, Heart and Lung Transplantation

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7 January 2021

Monitoring of human cytomegalovirus-specific CD4 and CD8 T-cell immunity in patients receiving solid organ transplantation

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7 January 2021

Inconsistent responses of cytomegalovirus-specific T cells to pp65 and IE-1 versus infected dendritic cells in organ transplant recipients

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7 January 2021

The number of activating KIR genes inversely correlates with the rate of CMV infection/reactivation in kidney transplant recipients

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7 January 2021

Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: pooled analysis of three clinical trials

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7 January 2021

High incidence of anticytomegalovirus drug resistance among D+R- kidney transplant recipients receiving preemptive therapy

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7 January 2021

Donor-derived CMV-specific T cells reduce the requirement for CMV-directed pharmacotherapy after allogeneic stem cell transplantation

1 reference

7 January 2021