Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the γ-hydroxyalkenal phospholipid hypothesis (Q26830841)

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English	Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the γ-hydroxyalkenal phospholipid hypothesis	scientific article

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scholarly article

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Europe PubMed Central

Critical insights into cardiovascular disease from basic research on the oxidation of phospholipids: the γ-hydroxyalkenal phospholipid hypothesis (English)

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cardiovascular disease

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based on heuristic

inferred from title

author name string

Robert G. Salomon

1

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Xiaodong Gu

2

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language of work or name

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publication date

21 November 2011

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Chemical Research in Toxicology

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24

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11

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1791-802

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Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

7 April 2017

Scavenger receptor BI: a scavenger receptor with a mission to transport high density lipoprotein lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

7 April 2017

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

7 April 2017

Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

7 April 2017

Discovery of carboxyethylpyrroles (CEPs): critical insights into AMD, autism, cancer, and wound healing from basic research on the chemistry of oxidized phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Lipid gymnastics: evidence of complete acyl chain reversal in oxidized phospholipids from molecular simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Platelet activation by low concentrations of intact oxidized LDL particles involves the PAF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Specific oxidized phospholipids inhibit scavenger receptor bi-mediated selective uptake of cholesteryl esters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Polyunsaturated phospholipids promote the oxidation and fragmentation of gamma-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

The relation of lipid peroxidation processes with atherogenesis: a new theory on atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Antiinflammatory properties of HDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Association between myeloperoxidase levels and risk of coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Evidence for a role of phospholipid oxidation products in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Aldehydic lipid peroxidation products derived from linoleic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Platelet-activating factor (PAF)-like oxidized phospholipids: relevance to atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Platelet-activating factor and related lipid mediators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Biologically active oxidized phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Interferon-gamma selectively induces Rab5a synthesis and processing in mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Analysis of epoxyeicosatrienoic and monohydroxyeicosatetraenoic acids esterified to phospholipids in human red blood cells by electrospray tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Phospholipase A2 activity of low density lipoprotein: evidence for an intrinsic phospholipase A2 activity of apoprotein B-100.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Role of oxidatively modified LDL in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 September 2017

Lysophosphatidylcholine is generated by spontaneous deacylation of oxidized phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

31 May 2018

Anti-inflammatory peptides grab on to the whiskers of atherogenic oxidized lipids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

31 May 2018

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

31 May 2018

Phospholipid hydroxyalkenals, a subset of recently discovered endogenous CD36 ligands, spontaneously generate novel furan-containing phospholipids lacking CD36 binding activity in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

A role for oxidized phospholipids in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Accumulation of oxidized lipid-protein complexes alters phagosome maturation in retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Products of lipid peroxidation induce missorting of the principal lysosomal protease in retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Temporary membrane distortion of vascular smooth muscle cells is responsible for their apoptosis induced by platelet-activating factor-like oxidized phospholipids and their degradation product, lysophosphatidylcholine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Novel bioactive phospholipids: practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine(1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Oxidized low density lipoprotein-induced inhibition of processing of photoreceptor outer segments by RPE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Lysophosphatidylcholine molecular species in low density lipoprotein of type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Oxidized phospholipids and isoprostanes in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3221896

28 November 2018

Lysophosphatidylcholine molecular species in low density lipoprotein and high density lipoprotein in alloxan-induced diabetic rats: effect of probucol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast atom bombardment tandem mass spectrometric identification of diacyl, alkylacyl, and alk-1-enylacyl molecular species of glycerophosphoethanolamine in human polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7 beta-hydroperoxycholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunochemical evidence supporting 2-pentylpyrrole formation on proteins exposed to 4-hydroxy-2-nonenal

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid peroxidation in low density lipoproteins from human plasma and egg yolk promotes accumulation of 1-acyl analogues of platelet-activating factor-like lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(Carboxyalkyl)pyrroles in human plasma and oxidized low-density lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory Platelet-activating Factor-like Phospholipids in Oxidized Low Density Lipoproteins Are Fragmented Alkyl Phosphatidylcholines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformation of an endogenous ligand in a membrane bilayer for the macrophage scavenger receptor CD36

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lipid whisker model of the structure of oxidized cell membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid oxidation and cardiovascular disease: introduction to a review series

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolevuglandin-protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total syntheses of bioactive oxidized ethanolamine phospholipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of vasopressor phospholipid in crude soybean lecithin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An oxidized derivative of phosphatidylcholine is a substrate for the platelet-activating factor acetylhydrolase from human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21870852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1021/TX200207Z

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release_ghvlrscjmrerzj3heviybcllnq

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