Mitochondrial function and dysfunction: an update (Q26824822)

M. Williams

series ordinal

2

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language of work or name

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September 2012

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Journal of Pharmacology and Experimental Therapeutics

published in

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volume

342

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page(s)

598-607

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issue

3

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When a theory of aging ages badly.

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Characterization of bioactive cell penetrating peptides from human cytochrome c: protein mimicry and the development of a novel apoptogenic agent

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Mitochondria: more than just a powerhouse

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Translational semantics and infrastructure: another search for the emperor's new clothes?

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The Alzheimer's disease mitochondrial cascade hypothesis: an update

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Mitochondrial dysfunction in cardiovascular disease

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Impact of PGC-1α on the topology and rate of superoxide production by the mitochondrial electron transport chain

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Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.

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A simplified model for mitochondrial ATP production.

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Mitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic models

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Energetics, epigenetics, mitochondrial genetics

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Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?

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Mitochondrial fission/fusion dynamics and apoptosis

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VDAC, a multi-functional mitochondrial protein as a pharmacological target

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The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

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Why are there no proven therapies for genetic mitochondrial diseases?

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Pharmacological targeting of mitochondrial complex I deficiency: the cellular level and beyond.

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Regulation and protection of mitochondrial physiology by sirtuins.

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Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

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Functionalized nanosystems for targeted mitochondrial delivery

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Therapeutic prospects for mitochondrial disease

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Mitochondria are sources of metabolic sink and arrhythmias

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Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

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7 January 2021

Free radicals and antioxidants - quo vadis?

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What is the mitochondrial permeability transition pore?

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The in-depth evaluation of suspected mitochondrial disease

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Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade

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Mitochondrial disease

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Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

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7 January 2021

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

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7 January 2021

A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures

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7 January 2021

Telomere dysfunction induces metabolic and mitochondrial compromise.

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

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The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis

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Targeting mitochondria for cancer therapy

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The role of mitochondria in insulin resistance and type 2 diabetes mellitus

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Mitochondrial permeability transition in apoptosis and necrosis

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Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

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Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway

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Mitochondrial morphology and cardiovascular disease

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Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1.

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7 January 2021

Oxidative shielding or oxidative stress?

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7 January 2021

Mitochondrial dysfunction in neurodegenerative diseases

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7 January 2021

Transgenic mouse models resistant to diet-induced metabolic disease: is energy balance the key?

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7 January 2021

Warburg revisited: regulation of mitochondrial metabolism by voltage-dependent anion channels in cancer cells

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7 January 2021

Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells

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7 January 2021

Mitochondria as a pharmacological target

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7 January 2021

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

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7 January 2021

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

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7 January 2021

Mitochondrial diseases in man and mouse

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7 January 2021

Genetics. Aging genes: the sirtuin story unravels

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Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

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7 January 2021

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7 January 2021

Mitochondrial fusion and fission in mammals

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7 January 2021

The role of mitochondria in apoptosis*.

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7 January 2021

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

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Inherited mitochondrial diseases of DNA replication

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7 January 2021

Strategies for reducing or preventing the generation of oxidative stress

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Targeting the mitochondrial permeability transition: cardiac ischemia-reperfusion versus carcinogenesis

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7 January 2021

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

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7 January 2021

Energy deficit in Huntington disease: why it matters

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Mitochondrial mutations: newly discovered players in neuronal degeneration.

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Organization and dynamics of human mitochondrial DNA.

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Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition pore

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7 January 2021

Role of Drp1, a key mitochondrial fission protein, in neuropathic pain

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7 January 2021

The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation

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7 January 2021

Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease

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7 January 2021

A brief history of the status of transposable elements: from junk DNA to major players in evolution

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7 January 2021

Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: Relevance to Alzheimer's disease

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7 January 2021

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

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7 January 2021

Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death

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7 January 2021

Transcranial laser therapy attenuates amyloid-β peptide neuropathology in amyloid-β protein precursor transgenic mice

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7 January 2021

Role of the mitochondrion in programmed necrosis

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7 January 2021

Olesoxime (TRO19622): A Novel Mitochondrial-Targeted Neuroprotective Compound

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7 January 2021

NSAIDs, Mitochondria and Calcium Signaling: Special Focus on Aspirin/Salicylates

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7 January 2021

Mitochondrial DNA damage and animal longevity: insights from comparative studies

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7 January 2021