Protein lipoxidation: Detection strategies and challenges (Q26824737)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Corinne M Spickett

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Alessandra Altomare

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

Francisco J Sánchez-Gómez

13 June 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Clara L Oeste

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Dolores Pérez-Sala

8

1 reference

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13 June 2020

author name string

Pedro Domingues

4

2 references

Crossref

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

M Rosário Domingues

2

1 reference

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13 June 2020

language of work or name

1 reference

August 2015

1 reference

1 August 2015

1 reference

19 November 2019

3 references

19 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

253-266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

Protein modifications by electrophilic lipoxidation products: adduct formation, chemical strategies and tandem mass spectrometry for their detection and identification

13 June 2020

cites work

1 reference

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The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways

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Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation

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The role of oxidized phospholipids in mediating lipoprotein(a) atherogenicity

7 April 2017

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Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding.

7 April 2017

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Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal

28 September 2017

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Identification of carbonylated lipids from different phospholipid classes by shotgun and LC-MS lipidomics

28 September 2017

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Role of 4-hydroxynonenal-protein adducts in human diseases

28 September 2017

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Analysis of protein carbonylation--pitfalls and promise in commonly used methods.

28 September 2017

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ROSics: chemistry and proteomics of cysteine modifications in redox biology.

28 September 2017

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Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol

28 September 2017

1 reference

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Impairment of aldehyde dehydrogenase-2 by 4-hydroxy-2-nonenal adduct formation and cardiomyocyte hypertrophy in mice fed a high-fat diet and injected with low-dose streptozotocin

28 September 2017

1 reference

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The formation of lipid hydroperoxide-derived amide-type lysine adducts on proteins: a review of current knowledge.

28 September 2017

1 reference

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Analysis of covalent modifications of proteins by oxidized phospholipids using a novel method of peptide enrichment

28 September 2017

1 reference

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Proteome-wide profiling of carbonylated proteins and carbonylation sites in HeLa cells under mild oxidative stress conditions

28 September 2017

1 reference

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4-Hydroxy-2-nonenal, an oxidative stress marker in crevicular fluid and serum in type 2 diabetes with chronic periodontitis

28 September 2017

1 reference

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Qualitative and quantitative evaluation of derivatization reagents for different types of protein-bound carbonyl groups

28 September 2017

1 reference

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Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies

28 September 2017

1 reference

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Role of lipid peroxidation-derived α, β-unsaturated aldehydes in vascular dysfunction

28 September 2017

1 reference

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Modification of cysteine residues by cyclopentenone prostaglandins: interplay with redox regulation of protein function

28 September 2017

1 reference

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Lipoxidation adducts with peptides and proteins: deleterious modifications or signaling mechanisms?

28 September 2017

1 reference

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Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.

28 September 2017

1 reference

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Advanced glycation end products and diabetic retinopathy.

28 September 2017

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Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging

28 September 2017

1 reference

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Mass spectrometric approaches for the identification and quantification of reactive carbonyl species protein adducts

28 September 2017

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Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links

28 September 2017

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Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease.

28 September 2017

1 reference

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Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry.

28 September 2017

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Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging.

28 September 2017

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Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides

28 September 2017

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Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics

28 September 2017

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Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses.

28 September 2017

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Shotgun lipidomics analysis of 4-hydroxyalkenal species directly from lipid extracts after one-step in situ derivatization

28 September 2017

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Protein modification by aldehydophospholipids and its functional consequences

28 September 2017

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Chemistry of phospholipid oxidation.

28 September 2017

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Oxidized phospholipids on apoB-100-containing lipoproteins: a biomarker predicting cardiovascular disease and cardiovascular events

28 September 2017

1 reference

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Nitro-oleic acid targets transient receptor potential (TRP) channels in capsaicin sensitive afferent nerves of rat urinary bladder

28 September 2017

1 reference

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Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents.

28 September 2017

1 reference

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Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction

28 September 2017

1 reference

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Proteomic studies on protein modification by cyclopentenone prostaglandins: expanding our view on electrophile actions.

28 September 2017

1 reference

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4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.

28 September 2017

1 reference

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Advanced lipoxidation end-products.

28 September 2017

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Electrophilic eicosanoids: Signaling and targets

28 September 2017

1 reference

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Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease

28 September 2017

1 reference

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Chemistry and biochemistry of lipid peroxidation products.

28 September 2017

1 reference

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Combined proteomic approaches for the identification of specific amino acid residues modified by 4-hydroxy-2-nonenal under physiological conditions

28 September 2017

1 reference

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Proteomic identification of carbonylated proteins and their oxidation sites

28 September 2017

1 reference

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Systems analysis of protein modification and cellular responses induced by electrophile stress

28 September 2017

1 reference

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Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.

28 September 2017

1 reference

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Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: protein carbonylation is diminished by ascorbic acid.

28 September 2017

1 reference

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Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms.

28 September 2017

1 reference

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A biotinylated analog of the anti-proliferative prostaglandin A1 allows assessment of PPAR-independent effects and identification of novel cellular targets for covalent modification

28 September 2017

1 reference

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Lipid peroxidation: physiological levels and dual biological effects

28 September 2017

1 reference

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Characterization of 4-hydroxy-2-nonenal-modified peptides by liquid chromatography-tandem mass spectrometry using data-dependent acquisition: neutral loss-driven MS3 versus neutral loss-driven electron capture dissociation

28 September 2017

1 reference

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Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators.

28 September 2017

1 reference

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Detection of catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

28 September 2017

1 reference

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Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives.

28 September 2017

1 reference

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Rapid characterization of covalent modifications to rat brain mitochondrial proteins after ex vivo exposure to 4-hydroxy-2-nonenal by liquid chromatography-tandem mass spectrometry using data-dependent and neutral loss-driven MS3 acquisition

28 September 2017

1 reference

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Study of protein targets for covalent modification by the antitumoral and anti-inflammatory prostaglandin PGA1: focus on vimentin

28 September 2017

1 reference

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Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective

28 September 2017

1 reference

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The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages

28 September 2017

1 reference

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Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival.

28 September 2017

1 reference

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Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators

28 September 2017

1 reference

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Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton

28 September 2017

1 reference

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Oxidized phospholipids, isolevuglandins, and atherosclerosis

28 September 2017

1 reference

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4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis.

28 September 2017

1 reference

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Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.

28 September 2017

1 reference

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The ABC's (and XYZ's) of peptide sequencing

28 September 2017

1 reference

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Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins.

28 September 2017

1 reference

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Detoxification of 4-hydroxynonenal (HNE) in keratinocytes: characterization of conjugated metabolites by liquid chromatography/electrospray ionization tandem mass spectrometry

28 September 2017

1 reference

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Fate of 4-hydroxynonenal in vivo: disposition and metabolic pathways

28 September 2017

1 reference

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Products of the isoprostane pathway: unique bioactive compounds and markers of lipid peroxidation

28 September 2017

1 reference

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15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

28 September 2017

1 reference

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15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

28 September 2017

1 reference

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Expression and characterization of Cys374 mutated human beta-actin in two different mammalian cell lines: impaired microfilament organization and stability

28 September 2017

1 reference

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Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes

28 September 2017

1 reference

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Quantitative chemoproteomics for site-specific analysis of protein alkylation by 4-hydroxy-2-nonenal in cells

28 September 2017

1 reference

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Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes

31 May 2018

1 reference

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Temporally controlled targeting of 4-hydroxynonenal to specific proteins in living cells

31 May 2018

1 reference

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Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

31 May 2018

1 reference

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4-HNE adduct stability characterized by collision-induced dissociation and electron transfer dissociation mass spectrometry

31 May 2018

1 reference

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Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity

31 May 2018

1 reference

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Methods for imaging and detecting modification of proteins by reactive lipid species

31 May 2018

1 reference

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Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Addition of electrophilic lipids to actin alters filament structure.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Increased aldehyde-modification of collagen type IV in symptomatic plaques--a possible cause of endothelial dysfunction.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Identification of 2-alkenals, 4-hydroxy-2-alkenals, and 4-hydroxy-2,6-alkadienals in exhaled breath condensate by UHPLC-HRMS and in breath by real-time HRMS.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Analytical method for lipoperoxidation relevant reactive aldehydes in human sera by high-performance liquid chromatography-fluorescence detection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Integrated quantification and identification of aldehydes and ketones in biological samples.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Ultrahigh performance liquid chromatography analysis of volatile carbonyl compounds in virgin olive oils

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Modulation of GSTP1-1 oligomerization by electrophilic inflammatory mediators and reactive drugs.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Differential carbonylation of cytoskeletal proteins in blood group O erythrocytes: potential role in protection against severe malaria.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Anti-inflammatory prostanoids: focus on the interactions between electrophile signaling and resolution of inflammation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Protein carbonylation: 2,4-dinitrophenylhydrazine reacts with both aldehydes/ketones and sulfenic acids.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Determination of malondialdehyde (MDA) by high-performance liquid chromatography in serum and liver as a biomarker for oxidative stress. Application to a rat model for hypercholesterolemia and evaluation of the effect of diets rich in phenolic antio

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477048

High-performance liquid chromatographic peak identification of 2,4-dinitrophenylhydrazine derivatives of lipid peroxidation aldehydes by photodiode array detection

28 November 2018

1 reference

12 December 2020

Chromatographic determination of low-molecular mass unsaturated aliphatic aldehydes with peroxyoxalate chemiluminescence detection after fluorescence labeling with 4-(N,N-dimethylaminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole

1 reference

12 December 2020

Use of Narrow Mass-Window, High-Resolution Extracted Product Ion Chromatograms for the Sensitive and Selective Identification of Protein Modifications

1 reference

12 December 2020

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction

1 reference

12 December 2020

15-Deoxy-Δ(12,14)-prostaglandin J2 exerts pro- and anti-inflammatory effects in mesangial cells in a concentration-dependent manner

1 reference

12 December 2020

LC-MS investigations on interactions between isolated β-lactoglobulin peptides and lipid oxidation product malondialdehyde

1 reference

12 December 2020

Comprehensive analysis of the lipophilic reactive carbonyls present in biological specimens by LC/ESI-MS/MS

1 reference

12 December 2020

Heterogeneity of peptide adducts with carbonylated lipid peroxidation products

1 reference

12 December 2020

Covalent binding of 4-hydroxynonenal to matrix metalloproteinase 13 studied by liquid chromatography-mass spectrometry

1 reference

12 December 2020

Prostaglandin A2 protein interactions and inhibition of cellular proliferation

1 reference

12 December 2020

10.1016/J.REDOX.2015.05.003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26072467%20AND%20SRC:MED&resulttype=core&format=json