The role of the T follicular helper cells in allergic disease (Q26824290)

language of work or name

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September 2012

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Cellular and Molecular Immunology

published in

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volume

9

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issue

5

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page(s)

386-9

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

7 April 2017

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A critical role for IL-21 in regulating immunoglobulin production

7 April 2017

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

7 April 2017

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Molecular and biological characterization of a murine ligand for CD40

7 April 2017

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IL-21 administration into the nostril alleviates murine allergic rhinitis

7 April 2017

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

7 April 2017

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Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells

7 April 2017

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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

7 April 2017

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Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

7 April 2017

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Sequential class switching is required for the generation of high affinity IgE antibodies

7 April 2017

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Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.

28 September 2017

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Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

28 September 2017

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

28 September 2017

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Unique maturation program of the IgE response in vivo

28 September 2017

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Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells

28 September 2017

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

28 September 2017

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Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

28 September 2017

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Transfer of allergic airway responses with antigen-primed CD4+ but not CD8+ T cells in brown Norway rats

28 September 2017

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Local production of IgG, IgA and IgE antibodies in grass pollen hay fever

28 September 2017

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Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.

28 September 2017

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Frequency of immunoglobulin E class switching is autonomously determined and independent of prior switching to other classes

31 May 2018

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Switch circles from IL-4-directed epsilon class switching from human B lymphocytes. Evidence for direct, sequential, and multiple step sequential switch from mu to epsilon Ig heavy chain gene.

31 May 2018

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Limbal vernal keratoconjunctivitis: clinical characteristics and immunoglobulin E expression compared with palpebral vernal

31 May 2018

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Transforming growth factor beta 1 increases IgA isotype switching at the clonal level.

31 May 2018

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Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production

31 May 2018

1 reference

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Higher risk of infantile atopic dermatitis from maternal atopy than from paternal atopy

31 May 2018

1 reference

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The distribution of IgE plasma cells in lymphoid and non-lymphoid tissues of high-IgE responder rats: differential localization of antigen-specific and 'bystander' components of the IgE response to inhaled antigen

31 May 2018

1 reference

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ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells.

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

IgE isotype switch and IgE production are enhanced in IL-21-deficient but not IFN-γ-deficient mice in a Th2-biased response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Interleukin-21 stimulates B-cell immunoglobulin E synthesis in human beings concomitantly with activation-induced cytidine deaminase expression and differentiation into plasma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Bcl6 is required for the IL-4-mediated rescue of the B cells from apoptosis induced by IL-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

A role for Bcl6 in sequential class switch recombination to IgE in B cells stimulated with IL-4 and IL-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

IgE⁺ memory B cells and plasma cells generated through a germinal-center pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Fluorescent in vivo detection reveals that IgE(+) B cells are restrained by an intrinsic cell fate predisposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Biosensor-based characterization of serum antibodies during development of an anti-IgE immunotherapeutic against allergy and asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.31

Regulation of human IgG subclass production by cytokines. IFN-gamma and IL-6 act antagonistically in the induction of human IgG1 but additively in the induction of IgG2

21 January 2018

1 reference

12 December 2020

B and T Lymphocyte Attenuator Suppresses IL-21 Production from Follicular Th Cells and Subsequent Humoral Immune Responses

1 reference

12 December 2020

Expression of Th-2 cytokines interleukin-4 and −5 and of Th-1 cytokine interferon-γ in ovalbumin-exposed sensitized Brown-Norway rats

1 reference

12 December 2020

Direct and sequential switching from mu to epsilon in patients with Schistosoma mansoni infection and atopic dermatitis

1 reference

12 December 2020

Successful transfer of late phase eosinophil infiltration in the lung by infusion of helper T cell clones

1 reference

12 December 2020

Adoptive transfer of allergen-specific CD4+ T cells induces airway inflammation and hyperresponsiveness in Brown-Norway rats

1 reference

12 December 2020

Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice

1 reference

12 December 2020

IgE versus IgG4 production can be differentially regulated by IL-10

1 reference

12 December 2020

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells

1 reference

12 December 2020

IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung

1 reference

12 December 2020

Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(epsilon) transcription of IL-4-stimulated B cells

1 reference

12 December 2020

S epsilon S mu and S epsilon S gamma switch circles in human nasal mucosa following ex vivo allergen challenge: evidence for direct as well as sequential class switch recombination

1 reference

12 December 2020

Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six-year prospective study

1 reference

12 December 2020

A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma

1 reference

12 December 2020

Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production

1 reference

12 December 2020

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones

1 reference

12 December 2020

The detection of IgE-secreting cells in the peripheral blood of patients with atopic dermatitis

1 reference

12 December 2020

Cytokine expression by germinal center cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/CMI.2012.31

1 reference

Dimensions Publication ID

601264

1017043981

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601264

1 reference

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