The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells? (Q26824147)

main subject

neoplastic stem cells

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author name string

Vicki Plaks

series ordinal

1

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Crossref

Niwen Kong

series ordinal

2

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Crossref

language of work or name

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5 March 2015

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16

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issue

3

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page(s)

225-38

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

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Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

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Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

7 April 2017

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7 April 2017

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

7 April 2017

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

7 April 2017

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7 April 2017

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Involvement of chemokine receptors in breast cancer metastasis

7 April 2017

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Immune cell promotion of metastasis

7 April 2017

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Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?

7 April 2017

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

7 April 2017

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

7 April 2017

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

7 April 2017

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

7 April 2017

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7 April 2017

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Creation of human tumour cells with defined genetic elements

7 April 2017

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Mutational landscape and significance across 12 major cancer types

7 April 2017

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The cancer stem cell niche--there goes the neighborhood?

7 April 2017

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Cancer stem cell niche: the place to be

7 April 2017

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TGF-β Receptor Inhibitors Target the CD44(high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma

7 April 2017

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Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

7 April 2017

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

7 April 2017

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

7 April 2017

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

7 April 2017

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Genetic alterations during colorectal-tumor development

7 April 2017

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Breast cancer-derived microparticles display tissue selectivity in the transfer of resistance proteins to cells

7 April 2017

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The difficulty of targeting cancer stem cell niches

7 April 2017

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7 April 2017

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Microenvironmental regulation of metastasis

7 April 2017

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7 April 2017

Fibroblasts in cancer

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The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

7 April 2017

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Dissemination and growth of cancer cells in metastatic sites

7 April 2017

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Influence of tumour micro-environment heterogeneity on therapeutic response

7 April 2017

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The causes and consequences of genetic heterogeneity in cancer evolution

7 April 2017

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Tumour heterogeneity and cancer cell plasticity

7 April 2017

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Intra-tumour heterogeneity: a looking glass for cancer?

7 April 2017

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Accessories to the crime: functions of cells recruited to the tumor microenvironment

7 April 2017

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Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

7 April 2017

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

7 April 2017

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Matrix metalloproteinases: regulators of the tumor microenvironment

7 April 2017

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

7 April 2017

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Metastasis: from dissemination to organ-specific colonization

7 April 2017

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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

7 April 2017

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

7 April 2017

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Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication

7 April 2017

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

7 April 2017

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

7 April 2017

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7 April 2017

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7 April 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Metastatic stem cells: sources, niches, and vital pathways

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Serpins promote cancer cell survival and vascular co-option in brain metastasis

28 September 2017

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Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17--a new mechanism of impaired antitumor immunity

28 September 2017

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The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment

28 September 2017

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Collective invasion in breast cancer requires a conserved basal epithelial program

28 September 2017

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TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition

28 September 2017

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A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway

28 September 2017

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Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis

28 September 2017

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28 September 2017

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Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis

28 September 2017

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28 September 2017

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Matricellular proteins: priming the tumour microenvironment for cancer development and metastasis

28 September 2017

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28 September 2017

TLRs as miRNA receptors

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Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

28 September 2017

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Cancer stem cells niche: a target for novel cancer therapeutics

28 September 2017

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Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis

28 September 2017

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Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.

28 September 2017

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Human melanoma metastasis in NSG mice correlates with clinical outcome in patients

28 September 2017

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Cancer stem cell dynamics in tumor progression and metastasis: is the microenvironment to blame?

28 September 2017

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Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition

28 September 2017

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Dynamic regulation of cancer stem cells and clinical challenges

28 September 2017

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Matrix metalloproteinases in vascular physiology and disease

28 September 2017

1 reference

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Mesenchymal stem cells in tumor development: emerging roles and concepts

28 September 2017

1 reference

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Cellular constituents of immune escape within the tumor microenvironment

28 September 2017

1 reference

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Mesenchymal stem cells provide an advantageous tumor microenvironment for the restoration of cancer stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy.

28 September 2017

1 reference

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Microenvironmental regulation of cancer stem cell phenotypes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

28 September 2017

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Homeostatic chemokine receptors and organ-specific metastasis

28 September 2017

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Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

28 September 2017

1 reference

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Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype

28 September 2017

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Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

28 September 2017

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Cancer to bone: a fatal attraction

28 September 2017

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Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

28 September 2017

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The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

The cancer stem cell: premises, promises and challenges

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Hypoxia potentiates glioma-mediated immunosuppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

The perivascular niche microenvironment in brain tumor progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Molecular mechanisms underlying tumor dormancy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Mesenchymal stem cells contribute to tumor cell proliferation by direct cell-cell contact interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Stem cells and the niche: a dynamic duo.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

EZH2 is essential for glioblastoma cancer stem cell maintenance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

The metastatic niche: adapting the foreign soil

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Cancer stem cells and survival pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Location, location, location: the cancer stem cell niche

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

"Destemming" cancer stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Fluctuations in pO2 in irradiated human melanoma xenografts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

CD44 attenuates metastatic invasion during breast cancer progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Quantifying transient hypoxia in human tumor xenografts by flow cytometry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Vascular phenotype in angiogenic and non-angiogenic lung non-small cell carcinomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Cancer. Circulating tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Cancer stem cells as 'units of selection'.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

CD133 and CD44 cell surface markers do not identify cancer stem cells in primary human gastric tumors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Hypoxic reactive oxygen species regulate the integrated stress response and cell survival.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4355577

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

28 November 2018

1 reference

12 December 2020

SnapShot: Bone Metastasis

1 reference

12 December 2020

Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells

1 reference

12 December 2020

Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis

1 reference

12 December 2020

Cancer stem cells: an evolving concept

1 reference

12 December 2020

Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity

1 reference

12 December 2020

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

1 reference

12 December 2020

ID genes mediate tumor reinitiation during breast cancer lung metastasis

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.STEM.2015.02.015

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.STEM.2015.02.015

1 reference

633702

633702

1 reference

1 reference

1 reference