Osthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative Medicine (Q26798190)

Evidence-based Complementary and Alternative Medicine

Europe PubMed Central

title

Osthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative Medicine (English)

0 references

1 reference

Zhong-Rong Zhang

1

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Wing Nang Leung

series ordinal

2

0 references

Ho Yee Cheung

series ordinal

3

0 references

Chun Wai Chan

series ordinal

4

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language of work or name

English

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publication date

2015

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published in

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volume

2015

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page(s)

919616

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copyright license

Creative Commons Attribution 3.0 Unported

start time

1 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

Growth inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole, a herbal compound, alleviates nucleus pulposus-evoked nociceptive responses through the suppression of overexpression of acid-sensing ion channel 3 (ASIC3) in rat dorsal root ganglion

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effect of osthol on apoptosis and bone resorption of osteoclasts cultured in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Main constituents from the seeds of Vietnamese Cnidium monnieri and cytotoxic activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Stimulation of Airway and Intestinal Mucosal Secretion by Natural Coumarin CFTR Activators

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole induces G2/M arrest and apoptosis in lung cancer A549 cells by modulating PI3K/Akt pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole regulates inflammatory mediator expression through modulating NF-κB, mitogen-activated protein kinases, protein kinase C, and reactive oxygen species

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole ameliorates insulin resistance by increment of adiponectin release in high-fat and high-sucrose-induced fatty liver rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

The effect of the major components of Fructus Cnidii on osteoblasts in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effects of osthole on migration and invasion in breast cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Neuroprotective effect of osthole on MPP+-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt/mTOR pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

5-Lipoxygenase inhibitors: a review of recent developments and patents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole, a potential antidiabetic agent, alleviates hyperglycemia in db/db mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthol is a use-dependent blocker of voltage-gated Na+ channels in mouse neuroblastoma N2A cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Fusarium graminearum growth inhibition due to glucose starvation caused by osthol

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Determination of osthol and its metabolites in a phase I reaction system and the Caco-2 cell model by HPLC-UV and LC-MS/MS

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effect of the Chinese herb extract osthol on IL-4-induced eotaxin expression in BEAS-2B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

A survey of Chinese herbal ingredients with liver protection activities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antitumor effects of Osthol from Cnidium monnieri: an in vitro and in vivo study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Chemical aspects of coumarin compounds for the prevention of hepatocellular carcinomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Cytotoxic activity of coumarins from the fruits of Cnidium monnieri on leukemia cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Inhibitory effect of the plant-extract osthole on L-type calcium current in NG108-15 neuronal cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Inhibition of concanavalin A-induced mice hepatitis by coumarin derivatives

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole increases glycosylation of hepatitis B surface antigen and suppresses the secretion of hepatitis B virus in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effect of Osthol on the proliferation and differentiate of osteoblasts in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antifungal activity of the osthol derivative JS-B against Phytophthora capsici

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthol regulates hepatic PPAR alpha-mediated lipogenic gene expression in alcoholic fatty liver murine

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Absorption and transport of 6 coumarins isolated from the roots of Angelica pubescens f. biserrata in human Caco-2 cell monolayer model

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Petroleum ether extract of Cnidium monnieri ameliorated scopolamine-induced amnesia through adrenal gland-mediated mechanism in male rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Determination of osthole in rat plasma by high-performance liquid chromatograph using cloud-point extraction

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Inhibitory effects of Angelica pubescens f. biserrata on 5-lipoxygenase and cyclooxygenase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antihaemostatic and antithrombotic effect of some antiplatelet agents isolated from Chinese herbs

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Vasorelaxation of rat thoracic aorta caused by osthole isolated from Angelica pubescens.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

The coumarin osthol attenuates the binding of thyrotropin-releasing hormone in rat pituitary GH4C1 cells

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthole suppresses seizures in the mouse maximal electroshock seizure model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

HPLC-based activity profiling of Angelica pubescens roots for new positive GABAA receptor modulators in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Neuroprotective effect of osthole against oxygen and glucose deprivation in rat cortical neurons: involvement of mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Neuroprotective effects of osthole pretreatment against traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthole improves aspects of spatial performance in ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Attenuation of experimental autoimmune encephalomyelitis in C57 BL/6 mice by osthole, a natural coumarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthol, a coumarin isolated from common cnidium fruit, enhances the differentiation and maturation of osteoblasts in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Effects of osthole on postmenopausal osteoporosis using ovariectomized rats; comparison to the effects of estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Effects of osthole on apoptosis and TGF-beta1 of hypertrophic scar fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthole suppresses hepatocyte growth factor (HGF)-induced epithelial-mesenchymal transition via repression of the c-Met/Akt/mTOR pathway in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Synthesis of N-hydroxycinnamides capped with a naturally occurring moiety as inhibitors of histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthole prevents anti-Fas antibody-induced hepatitis in mice by affecting the caspase-3-mediated apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Inhibitory effect of osthole on alcohol-induced fatty liver in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Reduction of isoprenaline-induced myocardial TGF-β1 expression and fibrosis in osthole-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

The relaxant action of osthole isolated from Angelica pubescens in guinea-pig trachea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Vasorelaxing effect of coumarins from Cnidium monnieri on rabbit corpus cavernosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Efficacy of osthol, a potent coumarin compound, in controlling powdery mildew caused by Sphaerotheca fuliginea

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Constituents, biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Prenylcoumarin with Rev-export inhibitory activity from Cnidii Monnieris Fructus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Osthol and isopimpinellin from Fructus cnidii for the control of Dactylogyrus intermedius in Carassius auratus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

HPLC determination and pharmacokinetics of osthole in rat plasma after oral administration of Fructus Cnidii extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Isolation and identification of metabolites of osthole in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Cyclic nucleotide regulation of store-operated Ca2+ influx in airway smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B4 production from dendritic cells via an IL-10-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Antibacterial and Anticoagulant Activities of Coumarins Isolated from the Flowers of Magydaris tomentosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

Immunomodulatory and anti-inflammatory activity of selected osthole derivatives

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole: a promising lead compound for drug discovery from a traditional Chinese medicine (TCM).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

In situ rats single pass perfusion intestinal absorption of the effectivein components in Radix Angelicae Pubescentis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Anti-inflammatory effect and mechanism of osthole in rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Advances in study on the pharmacological effects of active components of Chinese herbs on Alzheimer's disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effects of osthol on androgen level and nitric oxide synthase activity in castrate rats

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effect of osthol on memory impairment of mice in AlCl3-induced acute senile model

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Total coumarins from fruits of Cnidium monnieri inhibit formation and differentiation of multinucleated osteoclasts of rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

cAMP-elevating agents suppress dendritic cell function.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Antiproliferative effect of isopentenylated coumarins on several cancer cell lines

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effect of the plant-extract osthole on the relaxation of rabbit corpus cavernosum tissue in vitro.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effects of osthole on the isolated guinea-pig ileum and taeniae coli

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

Effects of osthole on isolated guinea pig heart atria.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4515521

[Quantitative study on the effect of osthole on proximal tibiae in ovariectomized (OVX) rats]

28 November 2018

1 reference

12 December 2020

Osthole improves fat milk-induced fatty liver in rats: modulation of hepatic PPAR-alpha/gamma-mediated lipogenic gene expression

1 reference

12 December 2020

A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells

1 reference

12 December 2020

Mechanism of osthole inhibition of vascular Ca(v)1.2 current

1 reference

12 December 2020

cGMP inhibits L-type Ca2+ channel currents through protein phosphorylation in rat pinealocytes

1 reference

12 December 2020

Effects of total coumarins of Fructus cnidii on skeleton of ovariectomized rats

1 reference

12 December 2020

Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats

1 reference

12 December 2020

Involvement of the cGMP pathway in the osthole-facilitated glutamate release in rat hippocampal nerve endings

1 reference

12 December 2020

Application of hollow fiber liquid phase microextraction coupled with high-performance liquid chromatography for the study of the osthole pharmacokinetics in cerebral ischemia hypoperfusion rat plasma

1 reference

12 December 2020

Effects of total coumarins of Cnidium monnieri on bone density and biomechanics of glucocorticoids-induced osteoporosis in rats

1 reference

12 December 2020

Synthetic derivatives of osthole for the prevention of hepatitis

1 reference

12 December 2020

Osthole, a natural coumarin, improves neurobehavioral functions and reduces infarct volume and matrix metalloproteinase-9 activity after transient focal cerebral ischemia in rats

1 reference

12 December 2020

Anthelmintic activity of the crude extracts, fractions, and osthole from Radix angelicae pubescentis against Dactylogyrus intermedius in goldfish (Carassius auratus) in vivo

1 reference

12 December 2020

[Effects of coumarins from cnidium monnieri on the function of pituitary-adrenocortical axis in kidney yang deficiency rats]

1 reference

12 December 2020

[Inhibitory effects of osthole, psoralen and aconitine on invasive activities of breast cancer MDA-MB-231BO cell line and the mechanisms]

1 reference

12 December 2020

Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress

1 reference

12 December 2020

[Effect of osthol and total coumarins of fructus cnidii on thyroid hormone and thyrotropic hormone in kidney-yang deficiency rats]

1 reference

12 December 2020

Therapeutic effect of osthole on hyperlipidemic fatty liver in rats

1 reference

12 December 2020

[Effects of osthol and total-coumarins from Cnidium monnieri on immunological function in kidney yang deficiency mice]

1 reference

12 December 2020

Coumarins from Cnidium monnieri and their antiosteoporotic activity

1 reference

12 December 2020

Antiproliferative effect in rat vascular smooth muscle cells by osthole, isolated from Angelica pubescens

1 reference

12 December 2020

[Effects and mechanisms of osthole on sciatica induced by lumber disc herniation]

1 reference

12 December 2020

Inhibition of platelet thromboxane formation and phosphoinositides breakdown by osthole from Angelica pubescens

1 reference

12 December 2020

[Effects of platycodin D in combination with different active ingredients of Chinese herbs on proliferation and invasion of 4T1 and MDA-MB-231 breast cancer cell lines]

1 reference

12 December 2020

[Inhibitory acting mechanism of psoralen-osthole on bone metastasis of breast cancer--an expatiation viewing from OPG/RANKL/RANK system]

1 reference

12 December 2020

Osthol ameliorates fat milk-induced fatty liver in mice by regulation of hepatic sterol regulatory element-binding protein-1c/2-mediated target gene expression

1 reference

12 December 2020

Pharmacokinetics of osthole in rat plasma using high-performance liquid chromatography

1 reference

12 December 2020

Inhibition of Platelet Thromboxane Formation and Phosphoinositides Breakdown by Osthole from Angelica pubescens

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F919616

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1155/2015/919616

1 reference

release_en2nj3z2wvghjm3u4bgmvtyxjm

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

26246843

1 reference