Metabolic reprogramming: the emerging concept and associated therapeutic strategies (Q26786595)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

5 July 2021

Metabolic reprogramming: the emerging concept and associated therapeutic strategies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

main subject

tumor microenvironment

1 reference

PubMed

cellular reprogramming technique

8 September 2020

1 reference

18 October 2020

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8 February 2021

1 reference

5 July 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Go J Yoshida

series ordinal

1

0 references

language of work or name

English

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publication date

6 October 2015

7 references

3 April 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

8 September 2020

18 October 2020

8 February 2021

5 July 2021

Journal of Experimental & Clinical Cancer Research

5 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

8 September 2020

18 October 2020

8 February 2021

5 July 2021

34

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26 February 2020

page(s)

111

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

26 February 2020

issue

1

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copyright license

6 references

3 April 2019

19 September 2019

8 September 2020

18 October 2020

8 February 2021

on focus list of Wikimedia project

5 July 2021

copyright status

copyrighted

0 references

ScienceSource

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exact match

https://scigraph.springernature.com/pub.10.1186/s13046-015-0221-y

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cites work

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

7 April 2017

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Otto Warburg's contributions to current concepts of cancer metabolism

7 April 2017

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THE METABOLISM OF TUMORS IN THE BODY

7 April 2017

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Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

7 April 2017

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Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

7 April 2017

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

7 April 2017

1 reference

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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

7 April 2017

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Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer

25 May 2017

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TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells

28 September 2017

1 reference

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Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1.

28 September 2017

1 reference

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In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors

28 September 2017

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28 September 2017

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Metformin inhibits the proliferation of human prostate cancer PC-3 cells via the downregulation of insulin-like growth factor 1 receptor.

28 September 2017

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28 September 2017

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28 September 2017

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Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

28 September 2017

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GLUT-1 expression is largely unrelated to both hypoxia and the Warburg phenotype in squamous cell carcinomas of the vulva

28 September 2017

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28 September 2017

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28 September 2017

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Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

28 September 2017

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Recent advances in drug repositioning for the discovery of new anticancer drugs

28 September 2017

1 reference

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Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial carcinoma.

28 September 2017

1 reference

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A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation

28 September 2017

1 reference

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Regulation of Wnt/β-catenin signaling by posttranslational modifications

28 September 2017

1 reference

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Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation.

28 September 2017

1 reference

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EpCAM expression in the prostate cancer makes the difference in the response to growth factors

28 September 2017

1 reference

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Increased expression of system large amino acid transporter (LAT)-1 mRNA is associated with invasive potential and unfavorable prognosis of human clear cell renal cell carcinoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

How does cancer cell metabolism affect tumor migration and invasion?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Statin induces inhibition of triple negative breast cancer (TNBC) cells via PI3K pathway

28 September 2017

1 reference

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Three-dimensional culture of sebaceous gland cells revealing the role of prostaglandin E2-induced activation of canonical Wnt signaling.

28 September 2017

1 reference

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Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells

28 September 2017

1 reference

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Genotyping analysis and ¹⁸FDG uptake in breast cancer patients: a preliminary research.

28 September 2017

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Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

28 September 2017

1 reference

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AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo

28 September 2017

1 reference

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Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells.

28 September 2017

1 reference

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Energy metabolism of cancer: Glycolysis versus oxidative phosphorylation (Review).

28 September 2017

1 reference

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The critical role of mast cell-derived hypoxia-inducible factor-1α in human and mice melanoma growth

28 September 2017

1 reference

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Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: increased expression of a CD44 variant isoform after chemotherapy

28 September 2017

1 reference

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High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Emerging roles of the FBW7 tumour suppressor in stem cell differentiation

28 September 2017

1 reference

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Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia

28 September 2017

1 reference

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Targeting cancer metabolism: a therapeutic window opens

28 September 2017

1 reference

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Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms.

28 September 2017

1 reference

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Oncogene addiction in gliomas: implications for molecular targeted therapy

28 September 2017

1 reference

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Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

MYC-induced cancer cell energy metabolism and therapeutic opportunities

28 September 2017

1 reference

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Environment-mediated drug resistance: a major contributor to minimal residual disease

28 September 2017

1 reference

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GLUT1 gene is a potential hypoxic marker in colorectal cancer patients.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Tumor metabolism: cancer cells give and take lactate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Redox regulation and its emerging roles in stem cells and stem-like cancer cells

28 September 2017

1 reference

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28 September 2017

1 reference

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The transport of glutamine into mammalian cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Cancer metabolism: facts, fantasy, and fiction

28 September 2017

1 reference

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28 September 2017

1 reference

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Pasteur effect and phosphofructokinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

The Pasteur effect and the relations between respiration and fermentation

28 September 2017

1 reference

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Cancer stem cells: constantly evolving and functionally heterogeneous therapeutic targets

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4595070

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation

31 May 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

The molecular machinery of Keilin's respiratory chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

Inhibition of Lactate Dehydrogenase to Treat Epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

Isolation and phenotypic characterization of colorectal cancer stem cells with organ-specific metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13046-015-0221-Y

Cancer stem cells: an evolving concept

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26445347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13046-015-0221-Y

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

26 February 2020

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13046-015-0221-y

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26445347%20AND%20SRC:MED&resulttype=core&format=json