SUMOylation: Novel Neuroprotective Approach for Alzheimer's Disease? (Q26783370)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Juliana B Hoppe

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Christianne G Salbego

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

September 2015

0 references

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

322-330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

Glial cells in (patho)physiology

4 June 2020

cites work

1 reference

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The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

7 April 2017

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Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin

7 April 2017

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7 April 2017

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Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization

28 September 2017

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SUMO and Alzheimer's disease

28 September 2017

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Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia

28 September 2017

1 reference

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Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells

28 September 2017

1 reference

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Reciprocal negative cross-talk between liver X receptors (LXRs) and STAT1: effects on IFN-γ-induced inflammatory responses and LXR-dependent gene expression

28 September 2017

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The global prevalence of dementia: a systematic review and metaanalysis

28 September 2017

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SUMO-1 is associated with a subset of lysosomes in glial protein aggregate diseases

28 September 2017

1 reference

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SUMO1 modulates Aβ generation via BACE1 accumulation.

28 September 2017

1 reference

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Neurological diseases as primary gliopathies: a reassessment of neurocentrism

28 September 2017

1 reference

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Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model

28 September 2017

1 reference

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Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2

28 September 2017

1 reference

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SUMO negatively regulates BACE expression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture.

28 September 2017

1 reference

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Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice

28 September 2017

1 reference

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Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Membrane lipid modification by docosahexaenoic acid (DHA) promotes the formation of α-synuclein inclusion bodies immunopositive for SUMO-1 in oligodendroglial cells after oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Inflammation in neurodegenerative diseases

28 September 2017

1 reference

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Amyloid-beta aggregates cause alterations of astrocytic metabolic phenotype: impact on neuronal viability

28 September 2017

1 reference

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Microglia activation and anti-inflammatory regulation in Alzheimer's disease

28 September 2017

1 reference

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Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy

28 September 2017

1 reference

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Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder.

28 September 2017

1 reference

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Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Sumoylation of amyloid precursor protein negatively regulates Abeta aggregate levels

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Emerging extranuclear roles of protein SUMOylation in neuronal function and dysfunction

28 September 2017

1 reference

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Glia proinflammatory cytokine upregulation as a therapeutic target for neurodegenerative diseases: function-based and target-based discovery approaches

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

SUMO on the road to neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Peroxisome proliferator-activated receptor agonist regulation of glial activation: relevance to CNS inflammatory disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Positive and negative regulation of APP amyloidogenesis by sumoylation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Modulation of inducible nitric oxide synthase expression by sumoylation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Amyloid beta-peptide is produced by cultured cells during normal metabolism

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

SUMO-1 conjugation blocks beta-amyloid-induced astrocyte reactivity.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Correlation of increased hippocampal Sumo3 with spatial learning ability in old C57BL/6 mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Differential SUMOylation of LXRalpha and LXRbeta mediates transrepression of STAT1 inflammatory signaling in IFN-gamma-stimulated brain astrocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Ubc9 gene polymorphisms and late-onset Alzheimer's disease in the Korean population: a genetic association study.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

SUMO-1 immunoreactivity co-localizes with phospho-Tau in APP transgenic mice but not in mutant Tau transgenic mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Glia as a therapeutic target: selective suppression of human amyloid-beta-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4567215

28 November 2018

Identifiers

DOI

10.14336/AD.2014.1205

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26425387%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

26425387

2 references