Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study (Q26782199)

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English	Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study	scientific article

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scholarly article

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28 September 2019

2 September 2020

Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study (English)

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nutritional deficiency disease

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28 September 2019

2 September 2020

complications of pregnancy

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19 March 2019

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20 August 2019

single-nucleotide polymorphism

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14 September 2019

fatty acid desaturases

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28 September 2019

fetal development

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Alison J McAfee

1

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Emeir M. McSorley

5

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Tanzy M Love

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Karin Engström

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Katherine Grzesik

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4 June 2020

Ayman Alhamdow

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Sally W Thurston

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Philip W Davidson

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4 June 2020

Edwin van Wijngaarden

11

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Conrad F Shamlaye

13

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G J Myers

14

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J J Strain

15

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publication date

December 2015

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1 December 2015

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13 March 2019

14 March 2019

19 March 2019

19 June 2019

30 June 2019

20 August 2019

14 September 2019

28 September 2019

2 September 2020

Prostaglandins, Leukotrienes and Essential Fatty Acids

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13 March 2019

14 March 2019

19 March 2019

19 June 2019

30 June 2019

20 August 2019

14 September 2019

28 September 2019

Europe PubMed Central

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4 June 2020

2 September 2020

102-103

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4 June 2020

13-20

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4 June 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

9 references

Europe PubMed Central

13 March 2019

Europe PubMed Central

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Europe PubMed Central

19 March 2019

Europe PubMed Central

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Europe PubMed Central

30 June 2019

Europe PubMed Central

20 August 2019

Europe PubMed Central

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Europe PubMed Central

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on focus list of Wikimedia project

0 references

Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life

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Associations of maternal long-chain polyunsaturated fatty acids, methyl mercury, and infant development in the Seychelles Child Development Nutrition Study

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7 April 2017

Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism

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cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family

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7 April 2017

Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles

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28 September 2017

Docosahexaenoic acid (DHA) supplementation in pregnancy differentially modulates arachidonic acid and DHA status across FADS genotypes in pregnancy

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28 September 2017

Supplementation with N-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genetic Variants in the FADS Gene: Implications for Dietary Recommendations for Fatty Acid Intake

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans

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28 September 2017

DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

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28 September 2017

Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration

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28 September 2017

Prenatal methyl mercury exposure in relation to neurodevelopment and behavior at 19 years of age in the Seychelles Child Development Study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Polymorphisms in iron homeostasis genes and urinary cadmium concentrations among nonsmoking women in Argentina and Bangladesh

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Maternal PUFA status but not prenatal methylmercury exposure is associated with children's language functions at age five years in the Seychelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin

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28 September 2017

Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genetic variants of the FADS gene cluster and ELOVL gene family, colostrums LC-PUFA levels, breastfeeding, and child cognition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genetic variation in polyunsaturated fatty acid metabolism and its potential relevance for human development and health

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Fatty acid supply to the human fetus

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28 September 2017

Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism

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28 September 2017

Do FADS genotypes enhance our knowledge about fatty acid related phenotypes?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Contribution of fish to intakes of micronutrients important for fetal development: a dietary survey of pregnant women in the Republic of Seychelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Essential fatty acid synthesis and its regulation in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Polyunsaturated fatty acids, inflammation, and immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Developmental quotient at 24 months and fatty acid composition of diet in early infancy: a follow up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 September 2017

Cadmium concentrations in human blood and urine are associated with polymorphisms in zinc transporter genes

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

https://pubmed.ncbi.nlm.nih.gov/26474818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations ov

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

The Seychelles child development study on neurodevelopmental outcomes in children following in utero exposure to methylmercury from a maternal fish diet: background and demographics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4746501

28 November 2018

Indices of fatty acid desaturase activity in healthy human subjects: effects of different types of dietary fat

1 reference

https://pubmed.ncbi.nlm.nih.gov/26474818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26474818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk

1 reference

https://pubmed.ncbi.nlm.nih.gov/26474818

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.PLEFA.2015.08.004

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474818%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

release_xlqahnd23fbazkxakwd7bzf2pu

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474818%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474818%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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