The role of CD44 in epithelial-mesenchymal transition and cancer development (Q26771509)

1

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Yijun Tian

2

0 references

Xun Yuan

3

0 references

Hua Wu

4

0 references

Qian Liu

5

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Kongming Wu

Creative Commons Attribution-NonCommercial 3.0 Unported

7

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language of work or name

English

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publication date

2015

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published in

OncoTargets and Therapy

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volume

8

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page(s)

3783-92

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copyright license

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer

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CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices.

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CD44 Variant 9 Serves as a Poor Prognostic Marker in Early Gastric Cancer, But Not in Advanced Gastric Cancer

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Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression

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CD44 regulates pancreatic cancer invasion through MT1-MMP

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MicroRNA-34a functions as an anti-metastatic microRNA and suppresses angiogenesis in bladder cancer by directly targeting CD44

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Combined epithelial-mesenchymal transition with cancer stem cell-like marker as predictors of recurrence after radical resection for gastric cancer

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Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling

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MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

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CDKL2 promotes epithelial-mesenchymal transition and breast cancer progression

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Oct-4 and Nanog promote the epithelial-mesenchymal transition of breast cancer stem cells and are associated with poor prognosis in breast cancer patients

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CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility

28 September 2017

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The addition of rituximab to CHOP therapy alters the prognostic significance of CD44 expression

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The low chamber pancreatic cancer cells had stem-like characteristics in modified transwell system: is it a novel method to identify and enrich cancer stem-like cells?

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CD44 standard and CD44v10 isoform expression on leukemia cells distinctly influences niche embedding of hematopoietic stem cells

28 September 2017

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Epithelial-to-mesenchymal transition mediates docetaxel resistance and high risk of relapse in prostate cancer.

28 September 2017

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CD44 variant 6 is associated with prostate cancer metastasis and chemo-/radioresistance

28 September 2017

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Activation of VCAM-1 and its associated molecule CD44 leads to increased malignant potential of breast cancer cells

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SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin

28 September 2017

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Breast cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts

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Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells

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Snail-induced epithelial-mesenchymal transition promotes cancer stem cell-like phenotype in head and neck cancer cells.

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Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma

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Emodin represses TWIST1-induced epithelial-mesenchymal transitions in head and neck squamous cell carcinoma cells by inhibiting the β-catenin and Akt pathways

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Maintenance of the stemness in CD44(+) HCT-15 and HCT-116 human colon cancer cells requires miR-203 suppression

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Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition

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CD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations

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Cancer stem-like cells enriched with CD29 and CD44 markers exhibit molecular characteristics with epithelial-mesenchymal transition in squamous cell carcinoma

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CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion

28 September 2017

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Raf-1 oncogenic signaling is linked to activation of mesenchymal to epithelial transition pathway in metastatic breast cancer cells

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Epithelial mesenchymal transition correlates with CD24+CD44+ and CD133+ cells in pancreatic cancer

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IL-6-induced epithelial-mesenchymal transition promotes the generation of breast cancer stem-like cells analogous to mammosphere cultures

28 September 2017

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The biology of head and neck cancer stem cells

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Fascin, an actin-bundling protein, promotes breast cancer progression in vitro

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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

28 September 2017

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CD44(+)/CD24(-) cells are transit progenitors and do not determine the molecular subtypes and clinical parameters in breast carcinomas

28 September 2017

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Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

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Podoplanin associates with CD44 to promote directional cell migration

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Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

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Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas.

28 November 2018

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CD44 is prognostic for overall survival in the NCI randomized trial on breast conservation with 25 year follow-up

28 November 2018

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High CD44s expression is associated with the EMT expression profile and intrahepatic dissemination of hepatocellular carcinoma after local ablation therapy

28 November 2018

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A CD44⁻/CD24⁺ phenotype is a poor prognostic marker in early invasive breast cancer

28 November 2018

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CD44 is protective during hyperoxia-induced lung injury

28 November 2018

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CD44 is of Functional Importance for Colorectal Cancer Stem Cells

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A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells

28 November 2018

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12 December 2020

CD44v6 expression is related to mesenchymal phenotype and poor prognosis in patients with colorectal cancer

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Possible contribution of CD44 variant 6 and nuclear beta-catenin expression to the formation of budding tumor cells in patients with T1 colorectal carcinoma

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CD44v8-10 is a cancer-specific marker for gastric cancer stem cells

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Decreased CD44 standard form expression correlates with prognostic variables in ovarian carcinomas

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Identifiers

DOI

10.2147/OTT.S95470

1 reference

release_micd2k7yb5ddfbtmm6u3hkdblq

4229908

Fatcat ID

0 references

4229908

1 reference

1 reference

1 reference