The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammation (Q26767123)

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10 March 2020

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20 December 2020

3 October 2022

The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26957481%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

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2 references

12 October 2019

18 October 2019

1 reference

12 October 2019

hemic and immune systems

1 reference

18 October 2019

Aleksander M. Grabiec

series ordinal

1

1 reference

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Tracy Hussell

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8 March 2016

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Seminars in Immunopathology

10 March 2020

1 July 2016

2 references

20 December 2020

3 October 2022

5 references

12 October 2019

18 October 2019

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page(s)

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Creative Commons Attribution 4.0 International

10 March 2020

copyright license

4 references

12 October 2019

18 October 2019

20 December 2020

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

3 October 2022

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TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine

7 April 2017

1 reference

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The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry

7 April 2017

1 reference

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Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells

7 April 2017

1 reference

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TNF-alpha, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

7 April 2017

1 reference

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TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.

7 April 2017

1 reference

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Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

7 April 2017

1 reference

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Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis

7 April 2017

1 reference

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C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

7 April 2017

1 reference

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Human CD14 mediates recognition and phagocytosis of apoptotic cells

7 April 2017

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Obesity and asthma: impact on severity, asthma control, and response to therapy

7 April 2017

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Phosphatidylserine receptors: enhancers of enveloped virus entry and infection

7 April 2017

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Phagocytosis of apoptotic cells in homeostasis

7 April 2017

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High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine

7 April 2017

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The resolution of inflammation: Principles and challenges

7 April 2017

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Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung

7 April 2017

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Apoptotic cells activate NKT cells through T cell Ig-like mucin-like-1 resulting in airway hyperreactivity

7 April 2017

1 reference

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HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin

7 April 2017

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TIM-1, a novel allergy and asthma susceptibility gene

7 April 2017

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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

7 April 2017

1 reference

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Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases

7 April 2017

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TAM receptors are pleiotropic inhibitors of the innate immune response

7 April 2017

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Surfactant Protein A Enhances Alveolar Macrophage Phagocytosis of Apoptotic Neutrophils

7 April 2017

1 reference

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

22 April 2017

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

7 April 2017

1 reference

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The AXL Receptor is a Sensor of Ligand Spatial Heterogeneity

7 April 2017

1 reference

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28 September 2017

Viral apoptotic mimicry

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Glucocorticoid-Augmented Efferocytosis Inhibits Pulmonary Pneumococcal Clearance in Mice by Reducing Alveolar Macrophage Bactericidal Function

28 September 2017

1 reference

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TREM-2 promotes macrophage survival and lung disease after respiratory viral infection

28 September 2017

1 reference

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The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

28 September 2017

1 reference

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PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

28 September 2017

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Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection.

28 September 2017

1 reference

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Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities

28 September 2017

1 reference

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Diversification of TAM receptor tyrosine kinase function

28 September 2017

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Eosinophils in the lung - modulating apoptosis and efferocytosis in airway inflammation.

28 September 2017

1 reference

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CD300b regulates the phagocytosis of apoptotic cells via phosphatidylserine recognition.

28 September 2017

1 reference

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Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

28 September 2017

1 reference

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Oxidative stress decreases functional airway mannose binding lectin in COPD

28 September 2017

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28 September 2017

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Simvastatin for the prevention of exacerbations in moderate-to-severe COPD

28 September 2017

1 reference

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Macrophages clean up: efferocytosis and microbial control

28 September 2017

1 reference

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An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo.

28 September 2017

1 reference

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Alveolar macrophages: plasticity in a tissue-specific context

28 September 2017

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The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target

28 September 2017

1 reference

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Biology of the TAM receptors

28 September 2017

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Depletion of alveolar macrophages during influenza infection facilitates bacterial superinfections

28 September 2017

1 reference

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Efferocytosis and lung disease

28 September 2017

1 reference

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Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications

28 September 2017

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Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation

28 September 2017

1 reference

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Obesity impairs apoptotic cell clearance in asthma

28 September 2017

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Defective efferocytosis by alveolar macrophages in IPF patients

28 September 2017

1 reference

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Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction

28 September 2017

1 reference

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Apoptotic cell instillation after bleomycin attenuates lung injury through hepatocyte growth factor induction.

28 September 2017

1 reference

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Role of Apoptosis in Amplifying Inflammatory Responses in Lung Diseases

28 September 2017

1 reference

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Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways

28 September 2017

1 reference

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Azithromycin for prevention of exacerbations of COPD.

28 September 2017

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CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen

28 September 2017

1 reference

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Participation of the receptor for advanced glycation end products in efferocytosis

28 September 2017

1 reference

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Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

28 September 2017

1 reference

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Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury.

28 September 2017

1 reference

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High mobility group protein B1 (HMGB1) in Asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls

28 September 2017

1 reference

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Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums

28 September 2017

1 reference

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Plasma concentrations of Gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor sAxl in sepsis and systemic inflammatory response syndromes

28 September 2017

1 reference

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Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

28 September 2017

1 reference

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TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

28 September 2017

1 reference

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Impairment of phagocytosis of apoptotic cells and its role in chronic airway diseases

28 September 2017

1 reference

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The distribution and function of phosphatidylserine in cellular membranes

28 September 2017

1 reference

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Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells

28 September 2017

1 reference

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Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease

28 September 2017

1 reference

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Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

28 September 2017

1 reference

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Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences.

28 September 2017

1 reference

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Cigarette smoke impairs clearance of apoptotic cells through oxidant-dependent activation of RhoA

28 September 2017

1 reference

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The phosphatidylserine receptor TIM-4 does not mediate direct signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

28 September 2017

1 reference

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Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

28 September 2017

1 reference

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Overexpression of apoptotic cell removal receptor MERTK in alveolar macrophages of cigarette smokers

28 September 2017

1 reference

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Ciliated epithelial cell lifespan in the mouse trachea and lung

28 September 2017

1 reference

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Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha

28 September 2017

1 reference

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Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma

28 September 2017

1 reference

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Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal

28 September 2017

1 reference

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Immunology of asthma and chronic obstructive pulmonary disease

28 September 2017

1 reference

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Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study

28 September 2017

1 reference

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The prolonged life-span of alveolar macrophages

28 September 2017

1 reference

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Identification of Tim4 as a phosphatidylserine receptor

28 September 2017

1 reference

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BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

28 September 2017

1 reference

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Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages

28 September 2017

1 reference

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A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation

28 September 2017

1 reference

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Innate immune activation in neutrophilic asthma and bronchiectasis.

28 September 2017

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Role of apoptosis in the pathogenesis of COPD and pulmonary emphysema

28 September 2017

1 reference

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Defective apoptotic cell phagocytosis attenuates prostaglandin E2 and 15-hydroxyeicosatetraenoic acid in severe asthma alveolar macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Alveolar wall apoptosis causes lung destruction and emphysematous changes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Fourteen-member macrolides promote the phosphatidylserine receptor-dependent phagocytosis of apoptotic neutrophils by alveolar macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Virus clearance through apoptosis-dependent phagocytosis of influenza A virus-infected cells by macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

28 September 2017

The immunology of asthma

1 reference

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Impact of alginate-producing Pseudomonas aeruginosa on alveolar macrophage apoptotic cell clearance

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Efferocytosis is an innate antibacterial mechanism

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

Glucocorticoids relieve collectin-driven suppression of apoptotic cell uptake in murine alveolar macrophages through downregulation of SIRPα.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

31 May 2018

1 reference

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Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4896990

RAGE signaling by alveolar macrophages influences tobacco smoke-induced inflammation.

31 May 2018

1 reference

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Priming of alveolar macrophages upon instillation of lipopolysaccharide in the human lung

21 January 2018

1 reference

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Azithromycin improves macrophage phagocytic function and expression of mannose receptor in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Increased apoptosis of neutrophils in induced sputum of COPD patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Therapeutic role for mannose-binding lectin in cigarette smoke-induced lung inflammation? Evidence from a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Human alveolar epithelial cells engulf apoptotic eosinophils by means of integrin- and phosphatidylserine receptor-dependent mechanisms: a process upregulated by dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Impaired macrophage phagocytosis in non-eosinophilic asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Phagocytosis of apoptotic eosinophils but not neutrophils by bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Immune-mediated phagocytosis and killing of Streptococcus pneumoniae are associated with direct and bystander macrophage apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Antiinflammatory Roles of Peroxisome Proliferator–activated Receptor γ in Human Alveolar Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

The effect of peroxisome proliferator-activated receptor-γ ligands on in vitro and in vivo models of COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Statin use is associated with reduced mortality in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Upregulation of Mer receptor tyrosine kinase signaling attenuated lipopolysaccharide-induced lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Animal models of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Phenotypic characterisation of alveolar macrophages and peripheral blood monocytes in COPD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Immunosuppressive effects of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0555-3

Smoking alters alveolar macrophage recognition and phagocytic ability: implications in chronic obstructive pulmonary disease

21 January 2018

1 reference

12 December 2020

Defect in efferocytosis leads to alternative activation of macrophages in Francisella infections

1 reference

12 December 2020

Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages

1 reference

12 December 2020

Differential role of CD80 and CD86 on alveolar macrophages in the presentation of allergen to T lymphocytes in asthma

1 reference

12 December 2020

Lovastatin Enhances Clearance of Apoptotic Cells (Efferocytosis) with Implications for Chronic Obstructive Pulmonary Disease

1 reference

12 December 2020

Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine

1 reference

12 December 2020

Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema

1 reference

12 December 2020

Apoptotic cells induce immunosuppression through dendritic cells: critical roles of IFN-gamma and nitric oxide

1 reference

12 December 2020

Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells

1 reference

12 December 2020

Correlation of lung surface area to apoptosis and proliferation in human emphysema

1 reference

12 December 2020

Glucocorticoids promote nonphlogistic phagocytosis of apoptotic leukocytes

1 reference

12 December 2020

Statin use and risk of COPD exacerbation requiring hospitalization

1 reference

12 December 2020

Eosinophil apoptosis and the resolution of airway inflammation in asthma

1 reference

12 December 2020

10.1007/S00281-016-0555-3

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26957481%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1036922352

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26957481%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26957481%20AND%20SRC:MED&resulttype=core&format=json