RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction (Q26269921)

Regulating synaptic membrane exocytosis 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Thomas C. Südhof

7

0 references

Josep Rizo

6

Josep Rizo

0 references

Pascal S Kaeser

1

Pascal S Kaeser

0 references

Xinran Liu

5

Xinran Liu

0 references

Irina Dulubova

4

Irina Dulubova

0 references

author name string

Lunbin Deng

2

0 references

Yun Wang

describes a project that uses

3

0 references

language of work or name

English

0 references

publication date

21 January 2011

0 references

published in

Cell

0 references

volume

144

0 references

page(s)

282-95

0 references

issue

2

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3063406/fullTextXML

inferred from PubMed Central ID database lookup

cites work

ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Deletion of CASK in mice is lethal and impairs synaptic function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM1alpha is required for presynaptic long-term potentiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Association of neuronal calcium channels with modular adaptor proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Microdomains of high calcium concentration in a presynaptic terminal

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM proteins and their role in synapse function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

cAMP/PKA signaling and RIM1alpha mediate presynaptic LTP in the lateral amygdala

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Regulation of membrane fusion in synaptic excitation-secretion coupling: speed and accuracy matter

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

A post-docking role for active zone protein Rim.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Single L-type calcium channel conductance with physiological levels of calcium in chick ciliary ganglion neurons.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

The role of Ca2+ channels in hippocampal mossy fiber synaptic transmission and long-term potentiation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Functional specialization of presynaptic Cav2.3 Ca2+ channels.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Calcium secretion coupling at calyx of Held governed by nonuniform channel-vesicle topography.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapse.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapses.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063406

Presynaptic Ca(2+) influx at a mouse central synapse with Ca(2+) channel subunit mutations

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21241895

12 December 2020

inferred from PubMed ID database lookup

Different types of calcium channels mediate central synaptic transmission

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21241895

12 December 2020

inferred from PubMed ID database lookup

Multiple calcium channel types control glutamatergic synaptic transmission in the hippocampus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21241895

12 December 2020

inferred from PubMed ID database lookup

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

NMR View: A computer program for the visualization and analysis of NMR data

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Short-term synaptic plasticity is altered in mice lacking synapsin I.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Autonomous function of synaptotagmin 1 in triggering synchronous release independent of asynchronous release

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zone

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Synaptotagmin I functions as a calcium regulator of release probability

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

A dual-Ca2+-sensor model for neurotransmitter release in a central synapse

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

A Novel Ubiquitous Form of Munc-18 Interacts with Multiple Syntaxins.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Examining synaptotagmin 1 function in dense core vesicle exocytosis under direct control of Ca2+

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Cytochemistry of Synapses: Selective Staining for Electron Microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2010.12.029

7 January 2021

10.1016/J.CELL.2010.12.029

Identifiers

DOI

1 reference

472556

472556

1 reference

1 reference

1 reference