Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly (Q26247960)

GOA release 2020-03-11

neuron apoptotic process

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GOA release 2020-03-11

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18

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Stacey Gabriel

11

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Maha Zaki

3

object named as

Maha S. Zaki

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Hongda Li

object named as

Hongda Li

1

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Katsuhito Yasuno

object named as

Katsuhito Yasuno

14

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author name string

Stephanie L. Bielas

2

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Samira Ismail

4

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Dorit Farfara

5

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Kyongmi Um

6

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Rasim O. Rosti

7

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Eric C. Scott

8

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Shu Tu

9

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Neil C. Chi

10

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Emine Z. Erson-Omay

12

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A. Gulhan Ercan-Sencicek

13

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Ahmet Okay Çağlayan

15

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Hande Kaymakçalan

16

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Barış Ekici

17

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Murat Gunel

19

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Joseph G. Gleeson

American Journal of Human Genetics

20

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language of work or name

English

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publication date

August 2016

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published in

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volume

99

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page(s)

501-510

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issue

2

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on focus list of Wikimedia project

ScienceSource

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cites work

Mutations in Citron Kinase Cause Recessive Microlissencephaly with Multinucleated Neurons

1 reference

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The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

7 April 2017

1 reference

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Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome

7 April 2017

1 reference

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Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

KIF14 and citron kinase act together to promote efficient cytokinesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron

7 April 2017

1 reference

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Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication

7 April 2017

1 reference

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Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy

7 April 2017

1 reference

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The structure of dimeric ROCK I reveals the mechanism for ligand selectivity

7 April 2017

1 reference

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A novel partner for the GTP-bound forms of rho and rac

7 April 2017

1 reference

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CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation

7 April 2017

1 reference

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Cytokinesis in Animal Cells

7 April 2017

1 reference

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A more efficient method to generate integration-free human iPS cells

7 April 2017

1 reference

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The nuts and bolts of AGC protein kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain

7 April 2017

1 reference

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Tissue-specific control of midbody microtubule stability by Citron kinase through modulation of TUBB3 phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Molecular genetics of human primary microcephaly: an overview.

28 September 2017

1 reference

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Katanin p80 regulates human cortical development by limiting centriole and cilia number

28 September 2017

1 reference

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Cortical neurogenesis in the absence of centrioles.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Primary cilia are required in a unique subpopulation of neural progenitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Microcephaly models in the developing zebrafish retinal neuroepithelium point to an underlying defect in metaphase progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Citron kinase mediates transition from constriction to abscission through its coiled-coil domain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Exome sequencing can improve diagnosis and alter patient management

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Citron kinase controls abscission through RhoA and anillin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Congenital microcephaly with a simplified gyral pattern: associated findings and their significance.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Many roads lead to primary autosomal recessive microcephaly

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

ASPM and citron kinase co-localize to the midbody ring during cytokinesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

28 September 2017

Flies without centrioles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Rho-dependent transfer of Citron-kinase to the cleavage furrow of dividing cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

Role of citron kinase as a target of the small GTPase Rho in cytokinesis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4974110

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27453578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Primary microcephaly with ASPM mutation shows simplified cortical gyration with antero-posterior gradient pre- and post-natally

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27453578