Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP (Q24816906)

1

Alex Pines

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Giuseppe Damante

5

Giuseppe Damante

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Franco Quadrifoglio

8

Franco Quadrifoglio

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Milena Romanello

4

Milena Romanello

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Nicoletta Bivi

3

Nicoletta Bivi

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author name string

Lorena Perrone

2

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Massimo Gulisano

6

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Mark R Kelley

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).

7

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language of work or name

English

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publication date

2005

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published in

Nucleic Acids Research

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volume

33

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issue

14

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page(s)

4379-94

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cites work

1 reference

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Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

7 April 2017

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Free radicals in the physiological control of cell function

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The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

7 April 2017

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Receptors for purines and pyrimidines

7 April 2017

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The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

7 April 2017

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Redox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cells

7 April 2017

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APE/Ref-1 is controlled by both redox and cAMP-dependent mechanisms in rat thyroid cells

7 April 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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Reactive oxygen species in cell signaling

7 April 2017

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NAD(P)H oxidase: role in cardiovascular biology and disease

7 April 2017

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Two essential but distinct functions of the mammalian abasic endonuclease

7 April 2017

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Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response

28 September 2017

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Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides.

28 September 2017

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Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition

28 September 2017

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Extracellular ATP stimulates the early growth response protein 1 (Egr-1) via a protein kinase C-dependent pathway in the human osteoblastic HOBIT cell line

28 September 2017

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Oxidant signals and oxidative stress

28 September 2017

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ATP as a signaling molecule: the exocrine focus.

28 September 2017

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Disturbances in purinergic [Ca2+]i signaling pathways in a transformed rat thyroid cell line

28 September 2017

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Current molecular models for NADPH oxidase regulation by Rac GTPase

28 September 2017

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Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis

28 September 2017

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Redox effector factor-1 regulates the activity of thyroid transcription factor 1 by controlling the redox state of the N transcriptional activation domain

28 September 2017

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Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

28 September 2017

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Molecular pharmacology of P2Y-receptors

28 September 2017

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28 September 2017

Going APE over ref-1.

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TSH controls Ref-1 nuclear translocation in thyroid cells

28 September 2017

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Cellular release of and response to ATP as key determinants of the set-point of signal transduction pathways.

28 September 2017

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An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

28 September 2017

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Signaling in human osteoblasts by extracellular nucleotides. Their weak induction of the c-fos proto-oncogene via Ca2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activ

28 September 2017

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Redox potential controls the structure and DNA binding activity of the paired domain

28 September 2017

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P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption

28 September 2017

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Activation of protein kinase C triggers its ubiquitination and degradation

28 September 2017

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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

28 September 2017

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The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

28 September 2017

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A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

28 September 2017

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Extracellular ATP is a mitogen for 3T3, 3T6, and A431 cells and acts synergistically with other growth factors

28 September 2017

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Purinergic agonist ATP is a comitogen in thyroid FRTL-5 cells

28 September 2017

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Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase.

28 September 2017

1 reference

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Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

31 May 2018

1 reference

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NADPH-dependent H2O2 generation and peroxidase activity in thyroid particular fraction.

31 May 2018

1 reference

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Hydrogen peroxide formation by cells treated with a tumor promoter

31 May 2018

1 reference

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Purinoceptor expression in regenerating skeletal muscle in the mdx mouse model of muscular dystrophy and in satellite cell cultures

31 May 2018

1 reference

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Hyperoxia-induced NAD(P)H oxidase activation and regulation by MAP kinases in human lung endothelial cells

28 November 2018

1 reference

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Activation of p90RSK and growth stimulation of multicellular tumor spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP.

28 November 2018

1 reference

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Mechanisms of P2 receptor-evoked DNA synthesis in thyroid FRTL-5 cells

28 November 2018

1 reference

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Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers

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1 reference

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The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils

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ApeI/Ref-I expression and cellular localization in human thyroid carcinoma cell lines

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Cholinergic nerves in the thyroid gland

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Extracellular ATP-induced production of hydrogen peroxide in porcine thyroid cells

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Differential cellular and subcellular expression of the human multifunctional apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme

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The DNA repair activity of human redox/repair protein APE/Ref-1 is inactivated by phosphorylation

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The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer

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The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress

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Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase

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Identifiers

DOI

10.1093/NAR/GKI751

1 reference

1464281

1464281

1 reference

1 reference

1 reference