Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection (Q24795912)

CD8-positive T-lymphocytes

19 September 2019

1 reference

8 April 2021

1 reference

1

Laura Papagno

0 references

Celsa A Spina

2

Celsa A Spina

0 references

Arnaud Marchant

3

Arnaud Marchant

0 references

Mariolina Salio

Mariolina Salio

4

0 references

Anele Waters

9

Anele Waters

0 references

Philippa Easterbrook

10

Philippa Easterbrook

0 references

Rod Dunbar

11

P Rod Dunbar

0 references

Dawn Shepherd

12

Dawn Shepherd

0 references

Vincenzo Cerundolo

Vincenzo Cerundolo

13

0 references

Vincent C Emery

Vincent Emery

14

0 references

Christopher P Conlon

16

Christopher Conlon

0 references

Andrew James McMichael

17

Andrew J McMichael

0 references

Douglas Richman

18

Douglas D Richman

0 references

Sarah Rowland-Jones

19

Sarah L Rowland-Jones

0 references

Victor Appay

20

Victor Appay

0 references

Susan J Little

6

Susan Little

0 references

author name string

Nathalie Rufer

5

0 references

Tao Dong

7

0 references

Gillian Chesney

8

0 references

Paul Griffiths

Creative Commons Attribution 4.0 International

15

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language of work or name

English

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publication date

February 2004

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1 February 2004

10 references

23 March 2019

31 July 2019

20 August 2019

19 September 2019

12 October 2019

18 October 2019

19 October 2019

1 July 2020

8 April 2021

25 October 2022

10 references

23 March 2019

31 July 2019

20 August 2019

19 September 2019

12 October 2019

18 October 2019

19 October 2019

1 July 2020

8 April 2021

25 October 2022

2

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page(s)

E20

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issue

2

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copyright license

10 references

23 March 2019

31 July 2019

20 August 2019

19 September 2019

12 October 2019

18 October 2019

19 October 2019

1 July 2020

8 April 2021

on focus list of Wikimedia project

25 October 2022

copyright status

copyrighted

0 references

ScienceSource

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cites work

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans

1 reference

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Thymic selection generates a large T cell pool recognizing a self-peptide in humans

7 April 2017

1 reference

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Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

7 April 2017

1 reference

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Lineage relationship and protective immunity of memory CD8 T cell subsets

7 April 2017

1 reference

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Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue

7 April 2017

1 reference

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Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

7 April 2017

1 reference

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

7 April 2017

1 reference

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Phenotypic analysis of antigen-specific T lymphocytes

7 April 2017

1 reference

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Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection

7 April 2017

1 reference

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Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Premature ageing of the immune system: the cause of AIDS?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Mature dendritic cells prime functionally superior melan-A-specific CD8+ lymphocytes as compared with nonprofessional APC.

28 September 2017

1 reference

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Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease

28 September 2017

1 reference

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Ageing of lymphocytes and lymphocytes in the aged

28 September 2017

1 reference

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Viral mechanisms of immune evasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Telomeres and HIV disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Cytomegalovirus infection and HIV-1 disease progression in infants born to HIV-1-infected women. Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection Study Group

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Faces and phases of human CD8 T-cell development.

28 September 2017

1 reference

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

28 September 2017

1 reference

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Diverse host responses and outcomes following simian immunodeficiency virus SIVmac239 infection in sooty mangabeys and rhesus macaques.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Frequency of multiple Epstein-Barr virus infections in T-cell-immunocompromised individuals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Replicative senescence: implications for in vivo aging and tumor suppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

CD8 naive T cell counts decrease progressively in HIV-infected adults

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Postthymic development of CD28-CD8+ T cell subset: age-associated expansion and shift from memory to naive phenotype.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

The influence of human immunodeficiency virus-1 on hematopoiesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Phenotypic and functional separation of memory and effector human CD8+ T cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Loss of primitive hematopoietic progenitors in patients with human immunodeficiency virus infection

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Cytomegalovirus infection and progression towards AIDS in haemophiliacs with human immunodeficiency virus infection

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Cytomegalovirus (CMV) and human immunodeficiency virus (HIV) burden, CMV end-organ disease, and survival in subjects with advanced HIV infection (AIDS Clinical Trials Group Protocol 360).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Cutting edge: rapid in vivo killing by memory CD8 T cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunization

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Proliferation requirements of cytomegalovirus-specific, effector-type human CD8+ T cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Primary immune responses to human CMV: a critical role for IFN-gamma-producing CD4+ T cells in protection against CMV disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

The fraction of perforin-expressing HIV-specific CD8 T cells is a marker for disease progression in HIV infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Diagnostic significance and clinical impact of quantitative assays for diagnosis of human cytomegalovirus infection/disease in immunocompromised patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=340937

Telomerase levels control the lifespan of human T lymphocytes

28 November 2018

1 reference

12 December 2020

Accelerated replicative senescence of the peripheral immune system induced by HIV infection

1 reference

12 December 2020

Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study

1 reference

12 December 2020

Dynamics of T cell responses in HIV infection

1 reference

12 December 2020

CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?

1 reference

12 December 2020

Characterization of CD4(+) CTLs ex vivo

1 reference

12 December 2020

Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors

1 reference

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

12 December 2020

Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions

1 reference

12 December 2020

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

1 reference

12 December 2020

Changes in thymic function with age and during the treatment of HIV infection

1 reference

12 December 2020

Increased expression of CD80, CD86 and CD70 on T cells from HIV-infected individuals upon activation in vitro: regulation by CD4+ T cells

1 reference

12 December 2020

Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.0020020

Identifiers

DOI

1 reference

2520071

2520071

1 reference

1 reference

1 reference