FADD adaptor in cancer (Q24795895)

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

Europe PubMed Central

title

FADD adaptor in cancer (English)

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2

Agnès Buzyn

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author name string

Léa Tourneur

series ordinal

1

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Gilles Chiocchia

series ordinal

3

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publication date

17 February 2005

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published in

Medical Immunology

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volume

4

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issue

1

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page(s)

1

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cites work

1 reference

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Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

7 April 2017

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FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

7 April 2017

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NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

7 April 2017

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Molecular evidence for the nuclear localization of FADD

7 April 2017

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Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

7 April 2017

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FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

7 April 2017

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

7 April 2017

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

7 April 2017

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Apoptosis by death factor

7 April 2017

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Genomic structure and mapping of human FADD, an intracellular mediator of lymphocyte apoptosis

7 April 2017

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

7 April 2017

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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

7 April 2017

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Absence or low expression of fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome

25 May 2017

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Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site.

28 September 2017

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Loss of FADD protein expression results in a biased Fas-signaling pathway and correlates with the development of tumoral status in thyroid follicular cells

28 September 2017

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Carboplatin induces Fas (APO-1/CD95)-dependent apoptosis of human tongue carcinoma cells: sensitization for apoptosis by upregulation of FADD expression

28 September 2017

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FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products

28 September 2017

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The death effector domain protein family: regulators of cellular homeostasis

28 September 2017

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The death domain superfamily: a tale of two interfaces?

28 September 2017

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Signaling pathways activated by daunorubicin

28 September 2017

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T cell-specific FADD-deficient mice: FADD is required for early T cell development

28 September 2017

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Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

28 September 2017

1 reference

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Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Cytotoxic drugs and the CD95 pathway

28 September 2017

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Membrane-bound Fas (Apo-1/CD95) ligand on leukemic cells: A mechanism of tumor immune escape in leukemia patients

28 September 2017

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FADD/MORT1, a signal transducer that can promote cell death or cell growth.

28 September 2017

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Dichotomy between naïve and memory CD4(+) T cell responses to Fas engagement

28 September 2017

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Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

28 September 2017

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Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

28 September 2017

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Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

28 September 2017

1 reference

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Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

28 September 2017

1 reference

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Human lung carcinomas express Fas ligand.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Oncogenic potential of guanine nucleotide stimulatory factor alpha subunit in thyroid glands of transgenic mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region

28 September 2017

1 reference

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Countering the 'counterattack' hypothesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Phosphorylation of FADD is critical for sensitivity to anticancer drug-induced apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

The requirements for Fas-associated death domain signaling in mature T cell activation and survival

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Sensitization of cancer cells treated with cytotoxic drugs to fas-mediated cytotoxicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=550674

Fas engagement accelerates liver regeneration after partial hepatectomy

28 November 2018

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12 December 2020

Functional expression of Fas (CD95) in acute myeloid leukemia cells in the context of CD34 and CD38 expression: possible correlation with sensitivity to chemotherapy

1 reference

12 December 2020

Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion

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12 December 2020

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

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12 December 2020

Fas ligand expression in nodal non-Hodgkin's lymphoma.

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12 December 2020

Cutting Edge: The Tumor Counterattack Hypothesis Revisited: Colon Cancer Cells Do Not Induce T Cell Apoptosis Via the Fas (CD95, APO-1) Pathway

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12 December 2020

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

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12 December 2020

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

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12 December 2020

Fas/APO-1 expression and function on malignant cells of hematologic and nonhematologic origin

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12 December 2020

Identifiers

DOI

10.1186/1476-9433-4-1

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Dimensions Publication ID

5040052

1050582333

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5040052

1 reference

1 reference

1 reference