Pirfenidone prevents the development of a vulnerable substrate for atrial fibrillation in a canine model of heart failure (Q24684669)

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Thomas H Everett

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Dulkon Rahmutula

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Jose M Guerra

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Emily Wilson

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Chunhua Ding

Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats

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language of work or name

English

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publication date

17 October 2006

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published in

Circulation

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volume

114

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page(s)

1703-12

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issue

16

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cites work

1 reference

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Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats

7 April 2017

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Increased vulnerability to atrial fibrillation in transgenic mice with selective atrial fibrosis caused by overexpression of TGF-beta1.

7 April 2017

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Alterations in atrial electrophysiology and tissue structure in a canine model of chronic atrial dilatation due to mitral regurgitation

28 September 2017

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Pirfenidone effectively reverses experimental liver fibrosis.

28 September 2017

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A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level

28 September 2017

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Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective

28 September 2017

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Differences in organization between acute and chronic atrial fibrillation in dogs

28 September 2017

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Gap junctional remodeling in relation to stabilization of atrial fibrillation in the goat

28 September 2017

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Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target

28 September 2017

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Effects of pirfenidone on procollagen gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis.

28 September 2017

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Pirfenidone improves renal function and fibrosis in the post-obstructed kidney

28 September 2017

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Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin-hamster model

28 September 2017

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Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters

28 September 2017

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Microfibrosis produces electrical load variations due to loss of side-to-side cell connections: a major mechanism of structural heart disease arrhythmias

28 September 2017

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Fibrosis in left atrial tissue of patients with atrial fibrillation with and without underlying mitral valve disease

28 September 2017

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Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis

30 May 2018

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Pirfenidone induces intercellular adhesion molecule-1 (ICAM-1) down-regulation on cultured human synovial fibroblasts.

30 May 2018

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Direction-dependent conduction abnormalities in a canine model of atrial fibrillation due to chronic atrial dilatation.

30 May 2018

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Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation.

28 November 2018

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Effects of angiotensin II type 1 receptor antagonist on electrical and structural remodeling in atrial fibrillation

28 November 2018

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Pirfenidone treatment decreases transforming growth factor-beta1 and matrix proteins and ameliorates fibrosis in chronic cyclosporine nephrotoxicity

28 November 2018

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Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs.

28 November 2018

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Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure

28 November 2018

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Inhibition of tumor necrosis factor and subsequent endotoxin shock by pirfenidone

28 November 2018

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Electrophysiologic characteristics of a dilated atrium in patients with paroxysmal atrial fibrillation and atrial flutter

28 November 2018

1 reference

12 December 2020

Differential expression of tissue inhibitors of metalloproteinases in the failing human heart

1 reference

12 December 2020

Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort

1 reference

12 December 2020

Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function

1 reference

12 December 2020

Matrix metalloproteinases and atrial remodeling in patients with mitral valve disease and atrial fibrillation

1 reference

12 December 2020

Atrial contractile dysfunction, fibrosis, and arrhythmias in a mouse model of cardiomyopathy secondary to cardiac-specific overexpression of tumor necrosis factor-{alpha}

1 reference

12 December 2020

Selective induction of matrix metalloproteinases and tissue inhibitor of metalloproteinases in atrial and ventricular myocardium in patients with atrial fibrillation

1 reference

12 December 2020

Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria

1 reference

12 December 2020

C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation

1 reference

12 December 2020

TNF-alpha and myocardial matrix metalloproteinases in heart failure: relationship to LV remodeling

1 reference

12 December 2020

Structural correlate of atrial fibrillation in human patients

1 reference

12 December 2020

Tissue structure and connexin expression of canine pulmonary veins

1 reference

12 December 2020

Fibrosis of the left atria during progression of heart failure is associated with increased matrix metalloproteinases in the rat

1 reference

12 December 2020

The functional role of structural complexities in the propagation of depolarization in the atrium of the dog. Cardiac conduction disturbances due to discontinuities of effective axial resistivity

1 reference

12 December 2020

Mechanisms for atrial arrhythmias associated with cardiomyopathy: a study of feline hearts with primary myocardial disease

1 reference

12 December 2020

Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy

1 reference

12 December 2020

Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy

1 reference

12 December 2020

Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension

1 reference

12 December 2020

10.1161/CIRCULATIONAHA.106.624320

Identifiers

DOI

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2587929

2587929

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1 reference

1 reference