The 5-HT3 receptor as a therapeutic target (Q24681066)

Expert Opinion on Therapeutic Targets

Europe PubMed Central

title

The 5-HT3 receptor as a therapeutic target (English)

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Andrew J Thompson

1

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Sarah C R Lummis

series ordinal

2

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language of work or name

English

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publication date

April 2007

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published in

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volume

11

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issue

4

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page(s)

527-40

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Patch Clamp Study of Serotonin-Gated Currents via 5-HT Type 3 Receptors by Using a Novel Approach SHAM for Receptor Channel Scanning

7 April 2017

1 reference

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Functional group interactions of a 5-HT3R antagonist

7 April 2017

1 reference

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The 5-HT3B subunit is a major determinant of serotonin-receptor function

7 April 2017

1 reference

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Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species

7 April 2017

1 reference

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WITHDRAWN: Drugs for preventing postoperative nausea and vomiting

7 April 2017

1 reference

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Structure and gating mechanism of the acetylcholine receptor pore

7 April 2017

1 reference

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

7 April 2017

1 reference

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Tropisetron improves deficits in auditory P50 suppression in schizophrenia

7 April 2017

1 reference

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Local treatment of tendinopathies and myofascial pain syndromes with the 5-HT3 receptor antagonist tropisetron

7 April 2017

1 reference

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Central antinociceptive activity of acetylsalicylic acid is modulated by brain serotonin receptor subtypes

7 April 2017

1 reference

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The molecular basis of the structure and function of the 5-HT3 receptor: a model ligand-gated ion channel (review)

7 April 2017

1 reference

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The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit

7 April 2017

2 references

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7 April 2017

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Promiscuous coassembly of serotonin 5-HT3 and nicotinic alpha4 receptor subunits into Ca(2+)-permeable ion channels

21 January 2018

1 reference

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Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells

7 April 2017

1 reference

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Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives

7 April 2017

1 reference

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Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine.

7 April 2017

1 reference

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Serotonin 5-HT(3) receptor mediation of pain and anti-nociception: implications for clinical therapeutics

28 September 2017

1 reference

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American Society of Clinical Oncology guideline for antiemetics in oncology: update 2006.

28 September 2017

1 reference

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A BIOCHEMICAL AND PHARMACOLOGICAL SUGGESTION ABOUT CERTAIN MENTAL DISORDERS.

28 September 2017

1 reference

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Mutations of L293 in transmembrane two of the mouse 5-hydroxytryptamine3A receptor alter gating and alcohol modulatory actions

28 September 2017

1 reference

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Evidence for a vagal pathophysiology for bulimia nervosa and the accompanying depressive symptoms

28 September 2017

1 reference

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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel.

28 September 2017

1 reference

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The use of antidepressants in functional gastrointestinal disorders: new uses for old drugs

28 September 2017

1 reference

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Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Co-expression of the 5-HT(3B) subunit with the 5-HT(3A) receptor reduces alcohol sensitivity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Effect of ondansetron, a 5-HT3 receptor antagonist, on fatigue in chronic hepatitis C: a randomised, double blind, placebo controlled study

28 September 2017

1 reference

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Effects of quinine, quinidine, and chloroquine on alpha9alpha10 nicotinic cholinergic receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Spatial orientation of the antagonist granisetron in the ligand-binding site of the 5-HT3 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Locating an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Intra-articular treatment of arthritides and activated osteoarthritis with the 5-HT3 receptor antagonist tropisetron. A double-blind study compared with methylprednisolone.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Analgesic effects of 5-HT3 receptor antagonists

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Spectrum of use and tolerability of 5-HT3 receptor antagonists

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Efficacy and tolerability of intravenous tropisetron in the treatment of fibromyalgia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Reassessing the benefits and risks of alosetron: what is its place in the treatment of irritable bowel syndrome?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Safety and tolerability of tegaserod in irritable bowel syndrome management

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

A cluster of novel serotonin receptor 3-like genes on human chromosome 3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Alosetron and irritable bowel syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Pharmacological aspects of anticancer drug-induced emesis with emphasis on serotonin release and vagal nerve activity

28 September 2017

1 reference

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A cytoplasmic region determines single-channel conductance in 5-HT3 receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Clozapine, quetiapine and olanzapine among addicted schizophrenic patients: towards testable hypotheses

28 September 2017

1 reference

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Prediction of 5-HT3 receptor agonist-binding residues using homology modeling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Plasma serotonin and histamine levels in hemodialysis-related pruritus are not significantly influenced by 5-HT3 receptor blocker and antihistaminic therapy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Ligand-gated ion channels in the enteric nervous system

28 September 2017

1 reference

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Association between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

The role of serotonin in the pathophysiology of irritable bowel syndrome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Fibromyalgia treatment with intravenous tropisetron administration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Serotonin receptor gene HTR3A variants in schizophrenic and bipolar affective patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Role of serotonin in memory impairment

28 September 2017

1 reference

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5-HT(3) receptor antagonists and anxiety; a preclinical and clinical review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. American Society of Clinical Oncology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Novel and highly potent 5-HT3 receptor agonists based on a pyrroloquinoxaline structure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Evidence that the atypical 5-HT3 receptor ligand, [3H]-BRL46470, labels additional 5-HT3 binding sites compared to [3H]-granisetron

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Nervous system distribution of the serotonin 5-HT3 receptor mRNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Treatment of pruritus: a new indication for serotonin type 3 receptor antagonists

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

The non-antiemetic uses of serotonin 5-HT3 receptor antagonists. Clinical pharmacology and therapeutic applications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Channel-forming peptide modulates transepithelial electrical conductance and solute permeability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Drugs which antagonize 5-hydroxytryptamine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Ionotrophic 5-hydroxytryptamine type 3 receptor activates the protein kinase C-dependent phospholipase D pathway in human T-cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

RETRACTED: Granisetron prevents nausea and vomiting during spinal anaesthesia for caesarean section.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Radioligand binding and photoaffinity labelling studies show a direct interaction of phenothiazines at 5-HT3 receptors.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Effects of the quinoline derivatives quinine, quinidine, and chloroquine on neuromuscular transmission

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Specific decreases in ethanol- but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Pharmacological characterization of the apparent splice variants of the murine 5-HT3 R-A subunit expressed in Xenopus laevis oocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

An electrophysiological investigation of the properties of 5-HT3 receptors of rabbit nodose ganglion neurones in culture

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

5-HT3 receptors are membrane ion channels

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

5-HT3 agonist 2-methylserotonin as a training drug in discrimination studies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Characterization of the novel 5-HT3 antagonists MDL 73147EF (dolasetron mesilate) and MDL 74156 in NG108-15 neuroblastoma x glioma cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Effects of ethanol on adenosine 5'-triphosphate-gated purinergic and 5-hydroxytryptamine receptors

30 May 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

5-HT3A receptor subunits in the rat medial nucleus of the solitary tract: subcellular distribution and relation to the serotonin transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Molecular determinants of picrotoxin inhibition of 5-hydroxytryptamine type 3 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

A Mutation in Transmembrane Domain II of the 5-Hydroxytryptamine3A Receptor Stabilizes Channel Opening and Alters Alcohol Modulatory Actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

General anesthetic-induced channel gating enhancement of 5-hydroxytryptamine type 3 receptors depends on receptor subunit composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Three putative N-glycosylation sites within the murine 5-HT3A receptor sequence affect plasma membrane targeting, ligand binding, and calcium influx in heterologous mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Identification and importance of N-glycosylation of the human 5-hydroxytryptamine3A receptor subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Novel mutations in 5-HT3A and 5-HT3B receptor genes not associated with clozapine response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

RETRACTED: Dolasetron reduces pain on injection of propofol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

New and emerging treatments for irritable bowel syndrome and functional dyspepsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Improved p50 auditory gating with ondansetron in medicated schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Deletion of the 5-HT3 receptor differentially affects behavior of males and females in the Porsolt forced swim and defensive withdrawal tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Reductions in and relations between "craving" and drinking in a prospective, open-label trial of ondansetron in adolescents with alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Ondansetron reduces the craving of biologically predisposed alcoholics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Altered response to meta-chlorophenylpiperazine in anorexia nervosa: support for a persistent alteration of serotonin activity after short-term weight restoration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

A controlled trial of ondansetron in the pruritus of cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Antipruritic effects of two different 5-HT3 receptor antagonists and an antihistamine in haemodialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Differential involvement of central 5-HT1B and 5-HT3 receptor subtypes in the antinociceptive effect of paracetamol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Structural implications of placing cationic residues at either the NH2- or COOH-terminus in a pore-forming synthetic peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

The pharmacological properties of the novel selective 5-HT3 receptor antagonist, alosetron, and its effects on normal and perturbed small intestinal transit in the fasted rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Analgesic effect of acetaminophen in humans: first evidence of a central serotonergic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.4.527

Treatment of chronic low back pain with tropisetron

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Expression of 5-HT3A receptors in cells of the immune system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

The safety of ondansetron for nausea and vomiting of pregnancy: a prospective comparative study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

The effect of granisetron, a 5-HT3 receptor antagonist, in the treatment of chronic fatigue syndrome patients--a pilot study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Local treatment of rheumatic diseases with the 5-HT3 receptor antagonist tropisetron

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Differential composition of 5-hydroxytryptamine3 receptors synthesized in the rat CNS and peripheral nervous system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

RETRACTED: Dolasetron for Preventing Postanesthetic Shivering

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994432

Treatment of irritable bowel syndrome

28 November 2018

1 reference

12 December 2020

Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention

1 reference

12 December 2020

The interaction of R(+)- and S(-)-zacopride with PCPA to modify rodent aversive behaviour

1 reference

12 December 2020

Antagonistic activities of N-3389, a newly synthesized diazabicyclo derivative, at 5-HT3 and 5-HT4 receptors

1 reference

12 December 2020

Localization of 5-HT3 receptors in the rat spinal cord: immunohistochemistry and in situ hybridization

1 reference

12 December 2020

Characterization of [3H]meta-chlorophenylbiguanide binding to 5-HT3 receptors in N1E-115 neuroblastoma cells

1 reference

12 December 2020

Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors

1 reference

12 December 2020

A phase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy

1 reference

12 December 2020

High affinity binding of azasetron hydrochloride to 5-hydroxytryptamine3 receptors in the small intestine of rats

1 reference

12 December 2020

Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial

1 reference

12 December 2020

Comparative study of [3H]ramosetron and [3H]granisetron binding in the cloned human 5-hydroxytryptamine3 receptors

1 reference

12 December 2020

Characterization of 5-HT3 receptors in intact N1E-115 neuroblastoma cells

1 reference

12 December 2020

10.1517/14728222.11.4.527

Identifiers

DOI

1 reference

27997

27997

1 reference

1 reference

1 reference