R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells (Q24669950)

1

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Gang Zeng

2

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Wade Otruba

3

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Michael D Thompson

4

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Peggy Muller

5

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Amanda Micsenyi

6

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Sandeep S Sekhon

7

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Lorenzo Leoni

8

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Satdarshan P S Monga

Epidermal growth factor receptor: a novel target of the Wnt/beta-catenin pathway in liver

9

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language of work or name

English

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publication date

May 2007

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published in

Journal of Hepatology

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volume

46

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issue

5

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page(s)

849-57

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cites work

1 reference

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

7 April 2017

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Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration

7 April 2017

1 reference

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

7 April 2017

1 reference

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Beta-catenin is temporally regulated during normal liver development

7 April 2017

1 reference

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Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention

7 April 2017

1 reference

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Opportunities for targeted therapies in hepatocellular carcinoma

7 April 2017

1 reference

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Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

28 September 2017

1 reference

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SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma

28 September 2017

1 reference

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The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis

28 September 2017

1 reference

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beta-catenin-mediated signaling: a molecular target for early chemopreventive intervention

28 September 2017

1 reference

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Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adip

28 September 2017

1 reference

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Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma

28 September 2017

1 reference

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Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

28 September 2017

1 reference

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Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-associated hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

28 September 2017

1 reference

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Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

28 September 2017

1 reference

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Beta-catenin antisense studies in embryonic liver cultures: role in proliferation, apoptosis, and lineage specification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Regulation of protein kinases in insulin, growth factor and Wnt signalling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Estimating the world cancer burden: Globocan 2000.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Truncated form of beta-catenin and reduced expression of wild-type catenins feature HepG2 human liver cancer cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Nuclear accumulation of mutated beta-catenin in hepatocellular carcinoma is associated with increased cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

beta-Catenin and met deregulation in childhood Hepatoblastomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3.

30 May 2018

1 reference

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The pharmacokinetics of etodolac enantiomers in the rat. Lack of pharmacokinetic interaction between enantiomers.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Morpholino oligonucleotide-triggered beta-catenin knockdown compromises normal liver regeneration

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1924913

Resolution of etodolac and antiinflammatory and prostaglandin synthetase inhibiting properties of the enantiomers

28 November 2018

1 reference

12 December 2020

Changing incidence of hepatocellular carcinoma in Japan

1 reference

12 December 2020

Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation

1 reference

12 December 2020

Cyclooxygenase-2 expression in hepatocellular carcinoma

1 reference

12 December 2020

COX-2 inhibitors and the kidney

1 reference

12 December 2020

The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update

1 reference

12 December 2020

10.1016/J.JHEP.2006.11.017

Identifiers

DOI

1 reference

4547585

4547585

1 reference

1 reference

1 reference