Pharmacological targeting of the serotonergic system for the treatment of obesity (Q24658013)

Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens

Europe PubMed Central

title

Pharmacological targeting of the serotonergic system for the treatment of obesity (English)

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Lora K Heisler

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author name string

Alastair S Garfield

series ordinal

1

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language of work or name

English

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publication date

15 January 2009

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published in

Journal of Physiology

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volume

587

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issue

1

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page(s)

49-60

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cites work

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Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors

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Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task

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28 September 2017

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28 September 2017

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3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole

28 September 2017

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Hyperphagia and Obesity Following Serotonin Depletion by Intraventricular p -Chlorophenylalanine

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Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.

30 May 2018

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Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice.

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The 5-HT2 receptor agonist MK-212 reduces food intake and increases resting but prevents the behavioural satiety sequence.

30 May 2018

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Effect of chronic treatment with TFMPP, a 5-HT1 receptor agonist, on food intake, weight gain, plasma insulin and neuropeptide mRNA expression in obese Zucker rats

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Increased exploratory activity and altered response to LSD in mice lacking the 5-HT(5A) receptor.

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Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

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Thermogenic effect of YM348, a novel 5-HT2C-receptor agonist, in rats

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Chronic paroxetine infusion influences macronutrient selection in male Sprague-Dawley rats

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Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia.

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Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.

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Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

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Reduction of Fat and Protein Intakes But Not Carbohydrate Intake Following Acute and Chronic Fluoxetine in Female Rats

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The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects

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Short-term effects of sibutramine (Reductil) on appetite and eating behaviour and the long-term therapeutic outcome

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Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors

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Reduced satiating effect of d -fenfluramine in serotonin 5-HT 2C receptor mutant mice

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Dissociation of the anorectic actions of 5-HTP and fenfluramine

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5-HT1B agonists induce anorexia at a postsynaptic site

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Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253

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7 January 2021