Identification of a chemical probe for NAADP by virtual screening (Q24654132)

3

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A. Ganesan

object named as

A Ganesan

10

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Antony Giuseppe Galione

object named as

Antony Galione

11

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author name string

Edmund Naylor

1

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Alexander M Lewis

4

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Raman Parkesh

5

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Akiko Mizote

6

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Daniel Rosen

7

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Justyn M Thomas

8

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Minoru Izumi

9

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Grant C Churchill

Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells

12

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language of work or name

English

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publication date

April 2009

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published in

Nature Chemical Biology

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volume

5

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issue

4

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page(s)

220-6

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Cell-permeant NAADP: a novel chemical tool enabling the study of Ca2+ signalling in intact cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

ZINC--a free database of commercially available compounds for virtual screening

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

NAADP mobilizes Ca(2+) from reserve granules, lysosome-related organelles, in sea urchin eggs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Drug discovery: a historical perspective

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Coordination of agonist-induced Ca2+-signalling patterns by NAADP in pancreatic acinar cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Unique inactivation properties of NAADP-sensitive Ca2+ release

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Activation and inactivation of Ca2+ release by NAADP+

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

The fluorescent toolbox for assessing protein location and function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Diversity-oriented synthesis: exploring the intersections between chemistry and biology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Desensitization of nicotinic ACh receptors: shaping cholinergic signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

The NAADP receptor: new receptors or new regulation?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Virtual screening of chemical libraries

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Integrating virtual screening in lead discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

The NAADP receptor: commentary on Billington et al.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Triazine dyes are agonists of the NAADP receptor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

NAADP-induced Ca2+ release -- a new signalling pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

The many roles of computation in drug discovery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

NAADP, cADPR and IP3 all release Ca2+ from the endoplasmic reticulum and an acidic store in the secretory granule area.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Contribution of the endoplasmic reticulum to the glucose-induced [Ca(2+)](c) response in mouse pancreatic islets

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Comparison of Shape-Matching and Docking as Virtual Screening Tools

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Variable selection and model validation of 2D and 3D molecular descriptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Role of the nicotinic acid group in NAADP receptor selectivity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Nicotinic acid adenine dinucleotide phosphate potentiates neurite outgrowth

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Ryanodine receptor type I and nicotinic acid adenine dinucleotide phosphate receptors mediate Ca2+ release from insulin-containing vesicles in living pancreatic beta-cells (MIN6).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Cyclic ADP-ribose in insulin secretion from pancreatic beta cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659327

Cyclic ADP-ribose in beta cells

28 November 2018

1 reference

12 December 2020

Structural determinants of nicotinic acid adenine dinucleotide phosphate important for its calcium-mobilizing activity

1 reference

12 December 2020

Fluorescent analogs of NAADP with calcium mobilizing activity

1 reference

12 December 2020

1 reference

12 December 2020

PPADS is a reversible competitive antagonist of the NAADP receptor

1 reference

12 December 2020

Scaffold hopping, synthesis and structure-activity relationships of 5,6-diaryl-pyrazine-2-amide derivatives: a novel series of CB1 receptor antagonists

1 reference

12 December 2020

Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release

1 reference

12 December 2020

Assessing the performance of OMEGA with respect to retrieving bioactive conformations

1 reference

12 December 2020

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.150

7 January 2021

inferred from DOI database lookup

Virtual ligand screening: strategies, perspectives and limitations

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.150

7 January 2021

inferred from DOI database lookup

A fast method of molecular shape comparison: A simple application of a Gaussian description of molecular shape

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.150

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.150

1 reference

Dimensions Publication ID

1050606261

0 references

1 reference

1 reference

PubMed publication ID

19234453

1 reference