T-cell regulation by CD46 and its relevance in multiple sclerosis (Q24653362)

Four viruses, two bacteria, and one receptor: membrane cofactor protein (CD46) as pathogens' magnet

Europe PubMed Central

title

T-cell regulation by CD46 and its relevance in multiple sclerosis (English)

0 references

0 references

Anne L Astier

1

0 references

language of work or name

English

0 references

publication date

June 2008

0 references

published in

Immunology

0 references

volume

124

0 references

issue

2

0 references

page(s)

149-54

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

The human CD46 molecule is a receptor for measles virus (Edmonston strain)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Control of regulatory T cell development by the transcription factor Foxp3

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Clinical parameters and HHV-6 active replication in relapsing-remitting multiple sclerosis patients

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

CD46: expanding beyond complement regulation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Human Herpesvirus 6 and Measles Virus Employ Distinct CD46 Domains for Receptor Function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

SLAM (CDw150) is a cellular receptor for measles virus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

A critical role for murine complement regulator crry in fetomaternal tolerance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Functional properties of membrane cofactor protein of complement

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Complement regulatory genes and hemolytic uremic syndromes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Human herpesvirus 7 infection increases the expression levels of CD46 and CD59 in target cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

T-cell regulation: with complements from innate immunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Multiple sclerosis: a battle between destruction and repair

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Holding T cells in check--a new role for complement regulators?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

How do CD4+CD25+ regulatory T cells control autoimmunity?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Decreased FOXP3 levels in multiple sclerosis patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Regulatory T cells and autoimmune disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

CD46: a complement regulator and pathogen receptor that mediates links between innate and acquired immune function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Familial haemolytic uraemic syndrome and an MCP mutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Adenovirus type 11 uses CD46 as a cellular receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Ligation of human CD46 with purified complement C3b or F(ab')(2) of monoclonal antibodies enhances isoform-specific interferon gamma-dependent nitric oxide production in macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Identification of the streptococcal M protein binding site on membrane cofactor protein (CD46).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

A functional interaction between CD46 and DLG4: a role for DLG4 in epithelial polarization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Functional modulation of human macrophages through CD46 (measles virus receptor): production of IL-12 p40 and nitric oxide in association with recruitment of protein-tyrosine phosphatase SHP-1 to CD46.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Induction of maturation of human blood dendritic cell precursors by measles virus is associated with immunosuppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Identification of a cytoplasmic Tyr-X-X-Leu motif essential for down regulation of the human cell receptor CD46 in persistent measles virus infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

GPI-anchored complement regulatory proteins in seminal plasma. An analysis of their physical condition and the mechanisms of their binding to exogenous cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Multiple isoforms of CD46 (membrane cofactor protein) serve as receptors for measles virus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Measles virus recognizes its receptor, CD46, via two distinct binding domains within SCR1-2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Human lymphocytes are more susceptible to measles virus than granulocytes, which is attributable to the phenotypic differences of their membrane cofactor protein (CD46).

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Alternatively spliced RNAs encode several isoforms of CD46 (MCP), a regulator of complement activation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Abnormal Tr1 differentiation in multiple sclerosis

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Mapping of the primary binding site of measles virus to its receptor CD46.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Mechanism of suppression of cell-mediated immunity by measles virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

CD46 is a cellular receptor for human herpesvirus 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Selective suppression of IL-12 production by human herpesvirus 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

CD46 is a cellular receptor for group B adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

CD46 in meningococcal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Cell signaling by the type IV pili of pathogenic Neisseria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Induction of a regulatory phenotype in human CD4+ T cells by streptococcal M protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Polymorphic expression of CD46 protein isoforms due to tissue-specific RNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2008.02821.X

Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Tissue-specific expression of CD46 protein isoforms due to production of RNA splice variants.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566619

Membrane cofactor protein (CD46) of complement. Processing differences related to alternatively spliced cytoplasmic domains

28 November 2018

1 reference

12 December 2020

Discrimination between alternatively spliced STP-A and -B isoforms of CD46

1 reference

12 December 2020

Emerging challenges in regulatory T cell function and biology

1 reference

12 December 2020

1 reference

12 December 2020

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

1 reference

12 December 2020

1 reference

12 December 2020

Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells

1 reference

12 December 2020

CD46/CD3 costimulation induces morphological changes of human T cells and activation of Vav, Rac, and extracellular signal-regulated kinase mitogen-activated protein kinase

1 reference

12 December 2020

Characterization of endogenous Chinese hamster ovary cell surface molecules that mediate T cell costimulation

1 reference

12 December 2020