AMPK and PPARdelta agonists are exercise mimetics (Q24652674)

1

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Michael Downes

2

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Ruth T Yu

3

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Emi Embler

4

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Yong-Xu Wang

5

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Ester Banayo

6

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Maria M Mihaylova

7

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Michael C Nelson

8

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Yuhua Zou

9

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Henry Juguilon

10

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Heonjoong Kang

11

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Reuben J Shaw

Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta

12

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language of work or name

English

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publication date

8 August 2008

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published in

Cell

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volume

134

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page(s)

405-15

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issue

3

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cites work

1 reference

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Regulation of muscle fiber type and running endurance by PPARdelta

7 April 2017

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7 April 2017

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

7 April 2017

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

7 April 2017

1 reference

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AMP-activated protein kinase plays a role in the control of food intake

7 April 2017

1 reference

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A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

7 April 2017

1 reference

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

7 April 2017

1 reference

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Myogenin and oxidative enzyme gene expression levels are elevated in rat soleus muscles after endurance training

7 April 2017

1 reference

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

7 April 2017

1 reference

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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

7 April 2017

1 reference

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

7 April 2017

1 reference

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Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift

7 April 2017

1 reference

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Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist.

28 September 2017

1 reference

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Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice

28 September 2017

1 reference

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Signaling pathways in skeletal muscle remodeling

28 September 2017

1 reference

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The role of AMP-activated protein kinase in mitochondrial biogenesis

28 September 2017

1 reference

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Understanding skeletal muscle adaptation to exercise training in humans: contributions from microarray studies

28 September 2017

1 reference

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Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise

28 September 2017

1 reference

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Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy

28 September 2017

1 reference

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Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor alpha by AMP-activated protein kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Variance-modeled posterior inference of microarray data: detecting gene-expression changes in 3T3-L1 adipocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Molecular basis of skeletal muscle plasticity--from gene to form and function

28 September 2017

1 reference

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AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

PPARdelta is a very low-density lipoprotein sensor in macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Physiology of professional road cycling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Myosin isoforms, muscle fiber types, and transitions

28 September 2017

1 reference

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The effect of endurance training on parameters of aerobic fitness

28 September 2017

1 reference

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Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy

28 September 2017

1 reference

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Adaptations of skeletal muscle to endurance exercise and their metabolic consequences

28 September 2017

1 reference

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Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models

28 September 2017

1 reference

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Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation

28 September 2017

1 reference

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Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.

30 May 2018

1 reference

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PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

PPARdelta activator GW-501516 has no acute effect on glucose transport in skeletal muscle

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Skeletal Muscle wasting and contractile performance in septic rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Coordinated changes in mitochondrial function and biogenesis in healthy and diseased human skeletal muscle

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Serial analysis of gene expression in the skeletal muscle of endurance athletes compared to sedentary men.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Effect of exercise intensity on skeletal muscle AMPK signaling in humans

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Exercise increases nuclear AMPK alpha2 in human skeletal muscle.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Regional differences in adipose tissue metabolism between sedentary and endurance-trained women.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706130

Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18674809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of exercise and insulin on mitogen-activated protein kinase signaling pathways in rat skeletal muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18674809

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myosin isoforms, muscle fiber types, and transitions

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.06.051

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2008.06.051

1 reference

1164119

1164119

1 reference

1 reference

1 reference