Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes (Q24651119)

5

object named as

John A Todd

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Sergey Nejentsev

1

object named as

Sergey Nejentsev

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author name string

David Riches

3

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Michael Egholm

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

4

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language of work or name

English

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publication date

17 April 2009

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published in

Science

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volume

324

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page(s)

387-9

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issue

5925

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cites work

1 reference

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A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3

7 April 2017

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Genome-wide association studies for complex traits: consensus, uncertainty and challenges

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Rare independent mutations in renal salt handling genes contribute to blood pressure variation

7 April 2017

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7 April 2017

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

7 April 2017

1 reference

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Genome sequencing in microfabricated high-density picolitre reactors

7 April 2017

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Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

7 April 2017

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

7 April 2017

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The impact of next-generation sequencing technology on genetics

7 April 2017

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Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

7 April 2017

1 reference

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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

7 April 2017

1 reference

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Genetic mapping in human disease

7 April 2017

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Common and rare variants in multifactorial susceptibility to common diseases

7 April 2017

1 reference

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IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

7 April 2017

1 reference

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Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes

28 September 2017

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Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

28 September 2017

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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

28 September 2017

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Intracellular pattern recognition receptors in the host response

28 September 2017

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A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

28 September 2017

1 reference

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The role of viruses in human diabetes.

28 September 2017

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Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene

28 September 2017

1 reference

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A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes

28 September 2017

1 reference

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Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

28 September 2017

1 reference

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The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19264985

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1167728

1 reference

412033

412033

1 reference

1 reference

1 reference