Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition (Q24648587)

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Heidi Melbostad

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William H Loomis

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Raul Coimbra

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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language of work or name

English

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publication date

June 2008

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1 reference

63

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page(s)

321-8

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issue

3

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cites work

1 reference

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

7 April 2017

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The NF-kappa B and I kappa B proteins: new discoveries and insights

7 April 2017

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Transcriptional control of the inflammatory response: a role for the CREB-binding protein (CBP)

7 April 2017

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Resuscitation affects microcirculatory polymorphonuclear leukocyte behavior after hemorrhagic shock: role of hypertonic saline and pentoxifylline.

7 April 2017

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Non-kinase second-messenger signaling: new pathways with new promise

28 September 2017

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Effects of phosphodiesterase inhibition on the inflammatory response after shock: role of pentoxifylline

28 September 2017

1 reference

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Injury, sepsis, and the regulation of Toll-like receptor responses

28 September 2017

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cAMP effector mechanisms. Novel twists for an 'old' signaling system

28 September 2017

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Therapeutic potential and strategies for inhibiting tumor necrosis factor-alpha

28 September 2017

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Relative contribution of transcription and translation to the induction of tumor necrosis factor-alpha by lipopolysaccharide

28 September 2017

1 reference

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Control of tumor necrosis factor gene expression

28 September 2017

1 reference

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RelA/p65 is a molecular target for the immunosuppressive action of protein kinase A

28 September 2017

1 reference

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Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes

28 September 2017

1 reference

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Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

28 September 2017

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Structural analysis of the rabbit TNF locus, containing the genes encoding TNF-beta (lymphotoxin) and TNF-alpha (tumor necrosis factor).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Regulation of NF-kappa B activation by MAP kinase cascades.

28 September 2017

1 reference

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-alpha and interleukin-1 beta by human mononuclear cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

The effects of a novel resuscitation strategy combining pentoxifylline and hypertonic saline on neutrophil MAPK signaling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Phosphodiesterase inhibition decreases nuclear factor-kappaB activation and shifts the cytokine response toward anti-inflammatory activity in acute endotoxemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-alpha synthesis: a novel resuscitation strategy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Nonspecific phosphodiesterase inhibition attenuates liver injury in acute endotoxemia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

LPS-stimulated PMN activation and proinflammatory mediator synthesis is downregulated by phosphodiesterase inhibition: role of pentoxifylline

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Intraarterial pulmonary pentoxifylline improves cardiac performance and oxygen utilization after hemorrhagic shock: a novel resuscitation strategy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis.

28 November 2018

1 reference

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Cyclic AMP inhibition of tumor necrosis factor alpha production induced by amyloidogenic C-terminal peptide of Alzheimer's amyloid precursor protein in macrophages: involvement of multiple intracellular pathways and cyclic AMP response element bindi

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Inhibition of the NF-kappaB transcriptional activity by protein kinase A.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Molecular control of tissue-specific expression at the mouse TNF locus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2664230

Hypertonic saline and pentoxifylline prevent lung injury and bacterial translocation after hemorrhagic shock

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18568240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18568240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pentoxifylline inhibits tumor necrosis factor production in septic shock

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18568240