Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc (Q24648398)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12237775%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc (English)

1 reference

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13 November 2019

5

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13 November 2019

Angela Greco

6

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13 November 2019

author name string

E Roccato

1

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13 November 2019

C Miranda

2

1 reference

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13 November 2019

V Ranzi

3

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13 November 2019

M Gishizki

4

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13 November 2019

language of work or name

English

0 references

publication date

1 September 2002

1 reference

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British Journal of Cancer

13 November 2019

published in

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13 November 2019

volume

87

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13 November 2019

page(s)

645-653

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13 November 2019

issue

6

1 reference

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

13 November 2019

cites work

1 reference

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Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation

7 April 2017

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The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain

7 April 2017

1 reference

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

7 April 2017

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Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA

7 April 2017

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The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

7 April 2017

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Role of tyrosine residues and protein interaction domains of SHC adaptor in VEGF receptor 3 signaling

7 April 2017

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Identification and characterization of novel substrates of Trk receptors in developing neurons

7 April 2017

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

7 April 2017

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Characterization and chromosomal mapping of the human TFG gene involved in thyroid carcinoma

7 April 2017

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Identification of Trk binding sites for SHC and phosphatidylinositol 3'-kinase and formation of a multimeric signaling complex

7 April 2017

1 reference

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The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins

7 April 2017

1 reference

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New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

7 April 2017

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A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3

7 April 2017

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

7 April 2017

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Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein

7 April 2017

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IRS-1 and IRS-2 are recruited by TrkA receptor and oncogenic TRK-T1.

28 September 2017

1 reference

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Characterization of TFG in mus musculus and Caenorhabditis elegans

28 September 2017

1 reference

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Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells.

28 September 2017

1 reference

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Specific TrkA survival signals interfere with different apoptotic pathways

28 September 2017

1 reference

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Molecular cloning and characterization of the human VGF promoter region

28 September 2017

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

28 September 2017

1 reference

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SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells

28 September 2017

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Regulatory elements in the promoter region of vgf, a nerve growth factor-inducible gene

28 September 2017

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Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells

28 September 2017

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28 September 2017

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A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides

28 September 2017

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The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes

28 September 2017

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Role of the TFG N-terminus and coiled-coil domain in the transforming activity of the thyroid TRK-T3 oncogene

30 May 2018

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Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

30 May 2018

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Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors

30 May 2018

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Collagen-homology domain 1 deletion mutant of Shc suppresses transformation mediated by neu through a MAPK-independent pathway.

30 May 2018

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Shc Binding to Nerve Growth Factor Receptor Is Mediated by the Phosphotyrosine Interaction Domain

21 January 2018

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The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

21 January 2018

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Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cell

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12237775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12237775

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6600544

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6600544

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12237775%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 November 2019

0 references

1 reference

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13 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12237775%20AND%20SRC:MED&resulttype=core&format=json