A high-affinity fully human anti-IL-6 mAb, 1339, for the treatment of multiple myeloma (Q24646864)

12

object named as

Pierfrancesco Tassone

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author name string

Mariateresa Fulciniti

1

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Teru Hideshima

2

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Claudine Vermot-Desroches

3

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Samantha Pozzi

4

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Puru Nanjappa

5

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Zhenxin Shen

6

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Nipun Patel

7

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Ernest S Smith

8

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Wei Wang

9

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Rao Prabhala

10

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Yu-Tzu Tai

11

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Nikhil C Munshi

SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells

14

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language of work or name

English

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publication date

1 December 2009

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published in

Clinical Cancer Research

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volume

15

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page(s)

7144-52

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issue

23

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cites work

1 reference

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Gp130 and the interleukin-6 family of cytokines

7 April 2017

1 reference

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Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma

7 April 2017

1 reference

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Targeted inhibition of interleukin-6 with CNTO 328 sensitizes pre-clinical models of multiple myeloma to dexamethasone-mediated cell death

27 September 2017

1 reference

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A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

27 September 2017

1 reference

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Optimizing the use of anti-interleukin-6 monoclonal antibody with dexamethasone and 140 mg/m2 of melphalan in multiple myeloma: results of a pilot study including biological aspects

27 September 2017

1 reference

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A clinically relevant SCID-hu in vivo model of human multiple myeloma

27 September 2017

1 reference

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Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence.

27 September 2017

1 reference

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Molecular mechanisms of novel therapeutic approaches for multiple myeloma

27 September 2017

1 reference

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Chimaeric anti-interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: a phase I dose-escalating study

27 September 2017

1 reference

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Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion

27 September 2017

1 reference

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Administration of an anti-interleukin-6 monoclonal antibody to patients with acquired immunodeficiency syndrome and lymphoma: effect on lymphoma growth and on B clinical symptoms

27 September 2017

1 reference

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Interleukin-6 in human multiple myeloma.

27 September 2017

1 reference

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Interleukin 6 is essential for in vivo development of B lineage neoplasms

27 September 2017

1 reference

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Non-invasive bone biopsy: a new method to analyse and display the three-dimensional structure of trabecular bone

27 September 2017

1 reference

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Biologic effects of anti-interleukin-6 murine monoclonal antibody in advanced multiple myeloma.

27 September 2017

1 reference

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Interleukin-6: an overview

27 September 2017

1 reference

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Biological and clinical aspects of interleukin 6.

27 September 2017

1 reference

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Evidence for the secretion of an osteoclast stimulating factor in myeloma.

27 September 2017

1 reference

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Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6.

30 May 2018

1 reference

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Inhibition of interleukin-6 signaling with CNTO 328 enhances the activity of bortezomib in preclinical models of multiple myeloma

30 May 2018

1 reference

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Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

28 November 2018

1 reference

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Immunomodulating IL-6 activity by murine monoclonal antibodies

28 November 2018

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12 December 2020

A microtomographic system for the nondestructive evaluation of bone architecture

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12 December 2020

Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells

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12 December 2020

Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-kappaB signaling pathways

1 reference

12 December 2020

Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors

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12 December 2020

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release

1 reference

12 December 2020

Cytokines involved in the progression of multiple myeloma

1 reference

12 December 2020

Interleukin-6 antisense deoxyoligonucleotides inhibit bone resorption by giant cells from human giant cell tumors of bone

1 reference

12 December 2020