Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice (Q24635187)

12

0 references

Hideyuki Okano

14

0 references

Masato Koike

8

0 references

Yohei Okada

2

Yohei Okada

0 references

Osahiko Tsuji

4

Osahiko Tsuji

0 references

Kanehiro Fujiyoshi

7

Kanehiro Fujiyoshi

0 references

Akimasa Yasuda

3

Akimasa Yasuda

0 references

author name string

Satoshi Nori

1

0 references

Yuichiro Takahashi

5

0 references

Yoshiomi Kobayashi

6

0 references

Yasuo Uchiyama

9

0 references

Eiji Ikeda

10

0 references

Yoshiaki Toyama

11

0 references

Masaya Nakamura

Proceedings of the National Academy of Sciences of the United States of America

13

0 references

language of work or name

English

0 references

publication date

4 October 2011

0 references

published in

0 references

volume

108

0 references

page(s)

16825-30

0 references

issue

40

0 references

cites work

Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Generation of germline-competent induced pluripotent stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Stem cells for the treatment of neurological disorders

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Mammalian neural stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

A more efficient method to generate integration-free human iPS cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Generation of induced pluripotent stem cells using recombinant proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Generation of mouse induced pluripotent stem cells without viral vectors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Neurons derived from transplanted neural stem cells restore disrupted neuronal circuitry in a mouse model of spinal cord injury.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Local and remote growth factor effects after primate spinal cord injury.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Neuronal progenitor transplantation and respiratory outcomes following upper cervical spinal cord injury in adult rats.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Promoting directional axon growth from neural progenitors grafted into the injured spinal cord

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants improve recovery after cervical spinal cord injury.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

The functional and neuroprotective actions of Neu2000, a dual-acting pharmacological agent, in the treatment of acute spinal cord injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Variation in the safety of induced pluripotent stem cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Degradation of chondroitin sulfate proteoglycans potentiates transplant-mediated axonal remodeling and functional recovery after spinal cord injury in adult rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Cell replacement therapies for central nervous system disorders.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

GABA and its receptors in the spinal cord

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Spinal cord transplants permit the growth of serotonergic axons across the site of neonatal spinal cord transection.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Transplantation of human neural stem cells for spinal cord injury in primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Retinoic-acid-concentration-dependent acquisition of neural cell identity during in vitro differentiation of mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Adenosine uptake and [3H]nitrobenzylthioinosine binding in developing rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Endogenous Repair after Spinal Cord Contusion Injuries in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Platelet-activating factor enhances the expression of vascular endothelial growth factor in normal human astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Brain-derived neurotrophic factor stimulates hindlimb stepping and sprouting of cholinergic fibers after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Nerve growth factor delivery by gene transfer induces differential outgrowth of sensory, motor, and noradrenergic neurites after adult spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Gene therapy for nervous system disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and modifies intraspinal circuitry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Transplantation of GABAergic neurons from ESCs attenuates tactile hypersensitivity following spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Comparison between fetal spinal-cord- and forebrain-derived neural stem/progenitor cells as a source of transplantation for spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Evaluation of human fetal neural stem/progenitor cells as a source for cell replacement therapy for neurological disorders: properties and tumorigenicity after long-term in vitro maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1108077108

Sprouting of primary afferent fibers after spinal cord transection in the rat.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189018

Experimental modeling of spinal cord injury: characterization of a force-defined injury device

28 November 2018

1 reference

12 December 2020

Involvement of GABA and glycine in recurrent inhibition of spinal motoneurons

1 reference

12 December 2020

The recovery of 5-HT immunoreactivity in lumbosacral spinal cord and locomotor function after thoracic hemisection

1 reference

12 December 2020

Direct agonists for serotonin receptors enhance locomotor function in rats that received neural transplants after neonatal spinal transection

1 reference

12 December 2020

Neutralizing intraspinal nerve growth factor blocks autonomic dysreflexia caused by spinal cord injury

1 reference

12 December 2020

Geron trial resumes, but standards for stem cell trials remain elusive

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1108077108

1 reference

2067746

ADS bibcode

2011PNAS..10816825N

0 references

2067746

1 reference

1 reference

1 reference