Intrinsically disordered proteins are potential drug targets (Q24633854)

Current Opinion in Chemical Biology

Europe PubMed Central

title

Intrinsically disordered proteins are potential drug targets (English)

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author name string

Steven J Metallo

series ordinal

1

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language of work or name

English

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publication date

August 2010

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published in

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volume

14

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page(s)

481-8

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issue

4

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cites work

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Inhibition of proteolysis and other posttranslational modifications with substrate-targeted inhibitors

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Identification of small molecule binding sites within proteins using phage display technology

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

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MYC oncogenes and human neoplastic disease

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Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein

27 September 2017

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

27 September 2017

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Recombinant EWS-FLI1 oncoprotein activates transcription

27 September 2017

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Detergent-like interaction of Congo red with the amyloid beta peptide

30 May 2018

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Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity.

28 November 2018

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Multiple independent binding sites for small-molecule inhibitors on the oncoprotein c-Myc.

28 November 2018

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Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules

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10.1016/J.CBPA.2010.06.169

28 November 2018

Identifiers

DOI

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2119583

2119583

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1 reference

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