IgM production by bone marrow plasmablasts contributes to long-term protection against intracellular bacterial infection (Q24631904)

1

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Derek D Jones

3

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Susan T Wittmer

4

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Katherine C MacNamara

5

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David L Woodland

6

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Gary M Winslow

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

7

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language of work or name

English

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publication date

15 January 2011

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published in

Journal of Immunology

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volume

186

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page(s)

1011-21

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issue

2

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cites work

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Functional memory B cells and long-lived plasma cells are generated after a single Plasmodium chabaudi infection in mice

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Generation of B cell memory to the bacterial polysaccharide alpha-1,3 dextran

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Persistent infection contributes to heterologous protective immunity against fatal ehrlichiosis

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The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

27 September 2017

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Pharmacokinetics and safety profile of the human anti-Pseudomonas aeruginosa serotype O11 immunoglobulin M monoclonal antibody KBPA-101 in healthy volunteers

27 September 2017

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Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

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Complement factor H-binding protein, a putative virulence determinant of Borrelia hermsii, is an antigenic target for protective B1b lymphocytes

27 September 2017

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Serotype-specific and age-dependent generation of pneumococcal polysaccharide-specific memory B-cell and antibody responses to immunization with a pneumococcal conjugate vaccine.

27 September 2017

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T-Cell-independent humoral immunity is sufficient for protection against fatal intracellular ehrlichia infection

27 September 2017

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Humoral immune response after primary rubella virus infection and after vaccination

27 September 2017

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Competence and competition: the challenge of becoming a long-lived plasma cell

27 September 2017

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An intradermal environment promotes a protective type-1 response against lethal systemic monocytotropic ehrlichial infection

27 September 2017

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B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses

27 September 2017

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Role of tumor necrosis factor alpha (TNF-alpha) and interleukin-10 in the pathogenesis of severe murine monocytotropic ehrlichiosis: increased resistance of TNF receptor p55- and p75-deficient mice to fatal ehrlichial infection

27 September 2017

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T-independent type II immune responses generate memory B cells

27 September 2017

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Essential role for humoral immunity during Ehrlichia infection in immunocompetent mice

27 September 2017

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Maintenance of serum antibody levels

27 September 2017

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Humoral immunity through immunoglobulin M protects mice from an experimental actinomycetoma infection by Nocardia brasiliensis.

27 September 2017

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Protective and nonprotective human immunoglobulin M monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan manifest different specificities and gene use profiles

27 September 2017

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Polyreactivity of antibody molecules

27 September 2017

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Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury

27 September 2017

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27 September 2017

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Extrafollicular antibody responses

27 September 2017

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27 September 2017

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Humoral immunity and long-lived plasma cells

27 September 2017

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Short-lived and long-lived bone marrow plasma cells are derived from a novel precursor population.

27 September 2017

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27 September 2017

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Purified lipopolysaccharide from Francisella tularensis live vaccine strain (LVS) induces protective immunity against LVS infection that requires B cells and gamma interferon

27 September 2017

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27 September 2017

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Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease

27 September 2017

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Immunoglobulin switch transcript production in vivo related to the site and time of antigen-specific B cell activation

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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CD11c expression identifies a population of extrafollicular antigen-specific splenic plasmablasts responsible for CD4 T-independent antibody responses during intracellular bacterial infection

27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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28 November 2018

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28 November 2018

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28 November 2018

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CD4 T-cell epitopes associated with protective immunity induced following vaccination of mice with an ehrlichial variable outer membrane protein

28 November 2018

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28 November 2018

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Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes

28 November 2018

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Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection.

28 November 2018

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Maintenance of long-term immunological memory by low avidity IgM-secreting cells in bone marrow after mucosal immunizations with cholera toxin adjuvant

28 November 2018

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Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow.

28 November 2018

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28 November 2018

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Maintenance of serological memory by polyclonal activation of human memory B cells.

28 November 2018

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Chemotactic responsiveness toward ligands for CXCR3 and CXCR4 is regulated on plasma blasts during the time course of a memory immune response.

28 November 2018

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Survival of long-lived plasma cells is independent of antigen.

28 November 2018

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High-avidity autoantibodies to cytokines.

28 November 2018

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Characterization of anti-Gal antibody-producing cells of baboons and humans

28 November 2018

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Identifiers

DOI

10.4049/JIMMUNOL.1002836

1 reference

988469

988469

1 reference

1 reference

1 reference