Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma (Q24630639)

2

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M Roh

3

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O E Franco

4

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S W Hayward

5

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M L Wills

6

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S A Abdulkadir

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

7

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language of work or name

English

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publication date

29 April 2010

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published in

Oncogene

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volume

29

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page(s)

2477-87

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issue

17

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cites work

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The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG

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The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint

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Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

7 April 2017

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Pim-1 associates with protein complexes necessary for mitosis

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Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia

7 April 2017

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Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate

27 September 2017

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A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells

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27 September 2017

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Chromosomal instability induced by Pim-1 is passage-dependent and associated with dysregulation of cyclin B1.

27 September 2017

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Pim family kinases enhance tumor growth of prostate cancer cells

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Expression and role of Foxa proteins in prostate cancer

27 September 2017

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RNA interference of achaete-scute homolog 1 in mouse prostate neuroendocrine cells reveals its gene targets and DNA binding sites

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

30 May 2018

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The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

21 January 2018

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Pim-1 expression in prostatic intraepithelial neoplasia and human prostate cancer

21 January 2018

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Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

21 January 2018

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Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells

21 January 2018

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PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation.

21 January 2018

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The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice

21 January 2018

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Neuroendocrine differentiation in prostatic carcinoma

31 March 2020

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Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

31 March 2020

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Comprehensive expression analysis of L-dopa decarboxylase and established neuroendocrine markers in neoadjuvant hormone-treated versus varying Gleason grade prostate tumors

31 March 2020

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Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer

31 March 2020

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Activation of the Erk mitogen-activated protein kinase pathway stimulates neuroendocrine differentiation in LNCaP cells independently of cell cycle withdrawal and STAT3 phosphorylation

31 March 2020

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