Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme (Q24629543)

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English	Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme	scientific article

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scholarly article

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Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme (English)

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Hyaluronan synthase 2

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GOA release 2020-03-11

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based on heuristic

inferred from title

John A. McDonald

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object named as

J A McDonald

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author name string

T D Camenisch

1

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A P Spicer

2

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T Brehm-Gibson

3

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J Biesterfeldt

4

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M L Augustine

5

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A Calabro

6

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S Kubalak

7

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S E Klewer

8

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language of work or name

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publication date

August 2000

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Journal of Clinical Investigation

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106

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349-60

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3

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Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Chromosomal localization of the human and mouse hyaluronan synthase genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Functional cloning of the cDNA for a human hyaluronan synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Adaptation of FACE methodology for microanalysis of total hyaluronan and chondroitin sulfate composition from cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Developmental defects in mouse embryos lacking N-cadherin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Molecular identification of a putative human hyaluronan synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Multiple essential functions of neuregulin in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

7 April 2017

Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Relationship between hyaluronan production and metastatic potential of mouse mammary carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Hyaluronan forms specific stable tertiary structures in aqueous solution: a 13C NMR study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Interactions between mitogenic stimuli, or, a thousand and one connections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

A heart segmental defect in the anterior-posterior axis of a transgenic mutant mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Hyaluronan fragments induce nitric-oxide synthase in murine macrophages through a nuclear factor kappaB-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Molecular cloning and characterization of a putative mouse hyaluronan synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Fibulin-1, vitronectin, and fibronectin expression during avian cardiac valve and septa development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Link protein is ubiquitously expressed in non-cartilaginous tissues where it enhances and stabilizes the interaction of proteoglycans with hyaluronic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Molecular regulation of atrioventricular valvuloseptal morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Death before birth: clues from gene knockouts and mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Section directed cryosectioning of specimens for scanning electron microscopy: a new method to study cardiac development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Signal transduction by cell adhesion receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

27 September 2017

Fibulin-1 is a ligand for the C-type lectin domains of aggrecan and versican.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Overproduction of hyaluronan by expression of the hyaluronan synthase Has2 enhances anchorage-independent growth and tumorigenicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Distinct mechanisms mediate the initial and sustained phases of integrin-mediated activation of the Raf/MEK/mitogen-activated protein kinase cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Inter-alpha-trypsin inhibitor proteoglycan family--a group of proteins binding and stabilizing the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Hyaluronan synthesis by mouse cumulus cells is regulated by interactions between follicle-stimulating hormone (or epidermal growth factor) and a soluble oocyte factor (or transforming growth factor beta1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Protein extracts from early embryonic hearts initiate cardiac endothelial cytodifferentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Solubilization and partial purification of hyaluronate synthetase from oligodendroglioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Hyaluronan as a propellant for epithelial movement: the development of semicircular canals in the inner ear of Xenopus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Effects of hyaluronic acid on cardiac cushion tissue cells in collagen matrix cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

30 May 2018

Effect of hyaluronidase treatment of intact cells on hyaluronate synthetase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 July 2018

TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Ultrastructural localization of microfibrillar fibulin-1 and fibulin-2 during heart development indicates a switch in molecular associations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Proteoglycans and proteins in the extracellular matrix of mouse cumulus cell-oocyte complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Delayed mammary tumor progression in Muc-1 null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Hyaluronate degradation affects ventricular function of the early postlooped embryonic rat heart in situ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=314332

28 November 2018

Localization of hyaluronan in mouse embryos during implantation, gastrulation and organogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic mesodermal defects in alpha 5 integrin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense inhibition of hyaluronan synthase-2 in human articular chondrocytes inhibits proteoglycan retention and matrix assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene targeting and generation of mutant mice for studies of cell-extracellular matrix interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardialization of the cardiac outflow tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ontogeny of hyaluronan secretion during early mouse development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microanalysis of enzyme digests of hyaluronan and chondroitin/dermatan sulfate by fluorophore-assisted carbohydrate electrophoresis (FACE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyaluronan is exocytosed from serous, but not mucous cells, of human nasal and tracheobronchial submucosal glands

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell anchorage permits efficient signal transduction between ras and its downstream kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial-mesenchymal transformation in the embryonic heart is mediated through distinct pertussis toxin-sensitive and TGFbeta signal transduction mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyaluronan activates mitogen-activated protein kinase via Ras-signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10930438

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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