The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells (Q24623981)

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English	The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells	scientific article

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scholarly article

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The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells (English)

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author name string

Sarah D Lamore

1

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Christopher M Cabello

2

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Georg T Wondrak

3

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language of work or name

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publication date

May 2010

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Cell Stress & Chaperones

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15

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3

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309-22

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https://scigraph.springernature.com/pub.10.1007/s12192-009-0145-6

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The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth

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7 April 2017

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

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7 April 2017

Induction by synaptic zinc of heat shock protein-70 in hippocampus after kainate seizures

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

7 April 2017

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

7 April 2017

A simple technique for quantitation of low levels of DNA damage in individual cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

7 April 2017

Significance of heat shock proteins in the skin upon UV exposure

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Synthesis and anticancer properties of water-soluble zinc ionophores

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Zinc protects endothelial cells from hydrogen peroxide via Nrf2-dependent stimulation of glutathione biosynthesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Hsp70B' regulation and function

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Let the sun shine in: mechanisms and potential for therapeutics in skin photodamage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Induction of the 72-kilodalton heat shock protein and protection from ultraviolet B-induced cell death in human keratinocytes by repetitive exposure to heat shock or 15-deoxy-delta(12,14)-prostaglandin J2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Poly(ADP-ribose) polymerases: managing genome stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Zinc pyrithione in alcohol-based products for skin antisepsis: persistence of antimicrobial effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Alkylating DNA damage stimulates a regulated form of necrotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

A multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Environmental pollutants and skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

What is the 'true' function of skin?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Effects of zinc acetate on splenocytes of endotoxemic mice: enhanced immune response, reduced apoptosis, and increased expression of heat shock protein 70.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Pyrithione, a zinc ionophore, inhibits NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Updated in vivo Methods for Evaluating Topical Antimicrobial Agents on Human Skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

Percutaneous absorption of zinc pyridinethione in monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

27 September 2017

H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

30 May 2018

Molecular cloning and expression of a cDNA encoding an apoptotic endonuclease DNase gamma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

30 May 2018

Comparative percutaneous absorption of pyrithiones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

30 May 2018

DNA damage by carbonyl stress in human skin cells

1 reference

https://api.crossref.org/works/10.1007%2FS12192-009-0145-6

21 January 2018

The roles of poly(ADP-ribose)-metabolizing enzymes in alkylation-induced cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Zinc induces ERK-dependent cell death through a specific Ras isoform.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Zinc pyrithione induces apoptosis and increases expression of Bim.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Studies on cytotoxic and genotoxic effects of N-hydroxypyridine-2-thione (Omadine) in L5178Y mouse lymphoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

Evaluation of the genotoxic potential of zinc pyrithione in the Salmonella mutagenicity (Ames) assay, CHO/HGPRT gene mutation assay and mouse micronucleus assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866994

28 November 2018

A double-blind randomized vehicle-controlled clinical trial investigating the effect of ZnPTO dose on the scalp vs. antidandruff efficacy and antimycotic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc pyrithione (Zinc Omadine) allergy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of molecular adaptation to sunlight--a new approach to photoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hsp70 synthesis induced by cupric sulfate and zinc sulfate in thermotolerant HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SAFETY EVALUATION OF ZINC 2-PYRIDINETHIOL 1-OXIDE IN A SHAMPOO FORMULATION

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryotoxicity of zinc pyrithione, an antidandruff chemical, in fish

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cadmium and zinc on solar-simulated light-irradiated cells: potential role of zinc-metallothionein in zinc-induced genoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PARP-1-induced cell death through inhibition of the MEK/ERK pathway in MNNG-treated HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19809895

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural characterization of bis(N-oxopyridine-2-thionato)zinc(II)

1 reference

https://api.crossref.org/works/10.1007%2FS12192-009-0145-6

7 January 2021

based on heuristic

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Identifiers

10.1007/S12192-009-0145-6

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https://api.fatcat.wiki/v0/release/lvtvfxrt4vdgrcyik6mmjjjpry

30 July 2022

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Dimensions Publication ID

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release_lvtvfxrt4vdgrcyik6mmjjjpry

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https://api.fatcat.wiki/v0/release/lvtvfxrt4vdgrcyik6mmjjjpry

30 July 2022

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1 reference

https://api.fatcat.wiki/v0/release/lvtvfxrt4vdgrcyik6mmjjjpry

30 July 2022

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1 reference

https://api.fatcat.wiki/v0/release/lvtvfxrt4vdgrcyik6mmjjjpry

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