CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity (Q24621344)

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English	CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity	scientific article

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scholarly article

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CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity (English)

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apoptotic process

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1 reference

based on heuristic

inferred from title

non-small-cell lung carcinoma

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based on heuristic

inferred from title

author name string

Giovanni L Carboni

1

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Boning Gao

2

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Masahiko Nishizaki

3

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Kai Xu

4

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John D Minna

5

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Jack A Roth

6

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Lin Ji

7

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language of work or name

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publication date

30 January 2003

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22

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4

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615-26

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Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)

1 reference

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7 April 2017

Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484891

7 April 2017

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

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7 April 2017

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium

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7 April 2017

Structure and regulation of voltage-gated Ca2+ channels

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7 April 2017

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484891

7 April 2017

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

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7 April 2017

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

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7 April 2017

The versatility and universality of calcium signalling

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7 April 2017

Mitochondrial control of cell death

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7 April 2017

BCL-2 family members and the mitochondria in apoptosis

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7 April 2017

Breaking the mitochondrial barrier

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27 September 2017

Calcium channel alpha(2)delta subunits-structure and Gabapentin binding

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27 September 2017

DAP kinase-a proapoptotic gene that functions as a tumor suppressor

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27 September 2017

Ionomycin and 2,5'-di(tertbutyl)-1,4,-benzohydroquinone elicit Ca2+-induced Ca2+ release from intracellular pools in Physarum polycephalum

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27 September 2017

Aberrant promoter methylation of multiple genes in non-small cell lung cancers.

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27 September 2017

The 'harmless' release of cytochrome c.

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27 September 2017

Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator

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27 September 2017

Low voltage activated calcium channels: from genes to function

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27 September 2017

Mitochondria as the central control point of apoptosis

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27 September 2017

The role of dynamic palmitoylation in Ca2+ channel inactivation

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27 September 2017

Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit

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27 September 2017

Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosis

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27 September 2017

Voltage-dependent Ca2+ channel alpha2delta auxiliary subunit: structure, function and regulation.

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27 September 2017

Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors

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27 September 2017

Molecular elements of ion permeation and selectivity within calcium channels

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27 September 2017

Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding

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27 September 2017

Voltage-dependent calcium channels: from structure to function

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27 September 2017

Molecular diversity of the calcium channel alpha2delta subunit

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484891

27 September 2017

Computerized polymorphic marker identification: experimental validation and a predicted human polymorphism catalog

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27 September 2017

Cloning and expression of a third calcium channel beta subunit

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27 September 2017

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

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27 September 2017

Cloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity.

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30 May 2018

Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.

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30 May 2018

Photochemically generated cytosolic calcium pulses and their detection by fluo-3.

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30 May 2018

The roles of the subunits in the function of the calcium channel.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484891

30 May 2018

A G-to-A single nucleotide polymorphism in the human alpha 2 delta 2 calcium channel subunit gene that maps at chromosome 3p21.3.

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21 January 2018

Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206134

21 January 2018

Mechanisms of mitochondrial membrane permeabilization

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21 January 2018

Synergistic inhibition of human lung cancer cell growth by adenovirus-mediated wild-type p53 gene transfer in combination with docetaxel and radiation therapeutics in vitro and in vivo

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28 November 2018

Calcium - a life and death signal

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28 November 2018

Hypermethylation of multiple genes in pancreatic adenocarcinoma

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Regulation of mitochondrial metabolism by ER Ca2+ release: an intimate connection

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12 December 2020

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Mitochondrial Ca(2+)homeostasis in the regulation of apoptotic and necrotic cell deaths

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Mitochondrial Mass and Membrane Potential in Celomocytes from the Earthworm Eisenia foetida: Studies with Fluorescent Probes in Single Intact Cells

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12 December 2020

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Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression

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https://pubmed.ncbi.nlm.nih.gov/12555074

12 December 2020

based on heuristic

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Identifiers

10.1038/SJ.ONC.1206134

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Springer Nature article ID

10.1038/sj.onc.1206134

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