High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography (Q24616137)

10

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Keith Hodgson

7

object named as

Keith O Hodgson

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author name string

Elena Bobyr

1

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Jonathan K Lassila

2

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Helen I Wiersma-Koch

3

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Timothy D Fenn

4

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Jason J Lee

5

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Ivana Nikolic-Hughes

6

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Douglas C Rees

8

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Britt Hedman

Journal of Molecular Biology

9

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language of work or name

English

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publication date

6 January 2012

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published in

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volume

415

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issue

1

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page(s)

102-17

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cites work

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Arginine Coordination in Enzymatic Phosphoryl Transfer: Evaluation of the Effect of Arg166 Mutations in Escherichia coli Alkaline Phosphatase † ‡

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Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102

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Trapping and visualization of a covalent enzyme-phosphate intermediate

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3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity

7 April 2017

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Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites

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Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase

7 April 2017

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Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase

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Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases

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Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis

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Likelihood-enhanced fast translation functions

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Coot: model-building tools for molecular graphics

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Refinement of macromolecular structures by the maximum-likelihood method

7 April 2017

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PHENIX: building new software for automated crystallographic structure determination

7 April 2017

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Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies

7 April 2017

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Catalytic promiscuity and the evolution of new enzymatic activities

7 April 2017

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A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases

7 April 2017

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Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

7 April 2017

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Small revisions to predicted distances around metal sites in proteins

7 April 2017

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The Cambridge Structural Database: a quarter of a million crystal structures and rising

7 April 2017

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7 April 2017

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Enzyme recruitment in evolution of new function

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An improved assay for nanomole amounts of inorganic phosphate

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QM/MM analysis suggests that Alkaline Phosphatase (AP) and nucleotide pyrophosphatase/phosphodiesterase slightly tighten the transition state for phosphate diester hydrolysis relative to solution: implication for catalytic promiscuity in the AP supe

7 April 2017

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Enzyme promiscuity: a mechanistic and evolutionary perspective

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Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine

27 September 2017

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Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution

27 September 2017

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Alkaline phosphatase catalysis is ultrasensitive to charge sequestered between the active site zinc ions

27 September 2017

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The power of vanadate in crystallographic investigations of phosphoryl transfer enzymes

27 September 2017

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The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds

27 September 2017

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Understanding the transition states of phosphodiester bond cleavage: insights from heavy atom isotope effects

27 September 2017

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The rate of hydrolysis of phosphomonoester dianions and the exceptional catalytic proficiencies of protein and inositol phosphatases

27 September 2017

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The depth of chemical time and the power of enzymes as catalysts.

27 September 2017

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Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes

27 September 2017

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Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase

27 September 2017

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Structure of binary and ternary complexes of zinc and cobalt carboxypeptidase A as determined by X-ray absorption fine structure

27 September 2017

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Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites

27 September 2017

1 reference

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Structural Aspects of Metal Liganding to Functional Groups in Proteins

27 September 2017

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Structure and mechanism of alkaline phosphatase

27 September 2017

1 reference

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Is the PTPase-vanadate complex a true transition state analogue?

27 September 2017

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Isotope-edited FTIR of alkaline phosphatase resolves paradoxical ligand binding properties and suggests a role for ground-state destabilization

27 September 2017

1 reference

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Pentavalent Organo-Vanadates as Transition State Analogues for Phosphoryl Transfer Reactions

30 May 2018

1 reference

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Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily

30 May 2018

1 reference

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X-ray absorption spectroscopic studies of zinc in the N-terminal domain of HIV-2 integrase and model compounds

30 May 2018

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Mechanisms of signaling and related enzymes

30 May 2018

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Promiscuity in alkaline phosphatase superfamily. Unraveling evolution through molecular simulations.

30 May 2018

1 reference

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Factors governing metal-ligand distances and coordination geometries of metal complexes.

28 November 2018

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Metal specificity is correlated with two crucial active site residues in Escherichia coli alkaline phosphatase

28 November 2018

1 reference

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Structural characterization of the zinc site in protein farnesyltransferase

28 November 2018

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Active site electronic structure and dynamics during metalloenzyme catalysis.

28 November 2018

1 reference

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ElaC encodes a novel binuclear zinc phosphodiesterase

28 November 2018

1 reference

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Alkaline phosphatase revisited: hydrolysis of alkyl phosphates

28 November 2018

1 reference

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XFIT - an Interactive EXAFSAnalysis Program

28 November 2018

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12 December 2020

Theoretical modeling of the reaction mechanism of phosphate monoester hydrolysis in alkaline phosphatase

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Refined structure of alkaline phosphatase from Escherichia coli at 2.8 A resolution

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12 December 2020

Structure of alkaline phosphatase with zinc/magnesium cobalt or cadmium in the functional metal sites

1 reference

12 December 2020