Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration (Q24613053)

1

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Bin Wang

2

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Jing Jing Li

3

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Ruishan Wang

4

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Qiyue Deng

5

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Shiyong Diao

6

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Yaomin Chen

7

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Raymond Xu

8

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Huaxi Xu

10

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Jung-Joon Sung

11

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Francesca-Fang Liao

Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development

12

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language of work or name

English

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publication date

8 August 2012

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published in

Journal of Neuroscience

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volume

32

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issue

32

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page(s)

10971-81

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cites work

1 reference

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Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

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Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

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Nedd4 controls animal growth by regulating IGF-1 signaling

7 April 2017

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The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

7 April 2017

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

7 April 2017

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NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

7 April 2017

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Regulation of SMN protein stability

7 April 2017

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Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

7 April 2017

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Identification of a set of genes with developmentally down-regulated expression in the mouse brain

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Oxidative stress regulates IGF1R expression in vascular smooth-muscle cells via p53 and HDAC recruitment

7 April 2017

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Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells

7 April 2017

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Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway

27 September 2017

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Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G⁹³A transgenic ALS mice

27 September 2017

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Protein disulfide isomerase and the endoplasmic reticulum in amyotrophic lateral sclerosis

27 September 2017

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Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc

27 September 2017

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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

27 September 2017

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The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease

27 September 2017

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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1.

27 September 2017

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27 September 2017

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Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels

27 September 2017

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27 September 2017

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The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice

27 September 2017

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Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury.

27 September 2017

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Corticomotoneuronal dysfunction in ALS patients with different SOD1 mutations

27 September 2017

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Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

27 September 2017

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Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Potential roles of insulin and IGF-1 in Alzheimer's disease.

27 September 2017

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Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor

27 September 2017

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27 September 2017

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Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients.

27 September 2017

1 reference

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27 September 2017

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Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n

27 September 2017

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ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

30 May 2018

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Zinc metabolism in the brain: relevance to human neurodegenerative disorders

30 May 2018

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SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor

30 May 2018

1 reference

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Zn2+ mediates ischemia-induced impairment of the ubiquitin-proteasome system in the rat hippocampus

28 November 2018

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Accumulation of labile zinc in neurons and astrocytes in the spinal cords of G93A SOD-1 transgenic mice

28 November 2018

1 reference

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A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681290

IGF-I specifically enhances axon outgrowth of corticospinal motor neurons

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681290

Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.

28 November 2018

1 reference

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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

28 November 2018

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Role of insulin-like growth factor 1 receptor signalling in cancer

28 November 2018

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inferred from PubMed ID database lookup

12 December 2020

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Insulin-like growth factor-1 receptors in human spinal cord: changes in amyotrophic lateral sclerosis

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inferred from PubMed ID database lookup

12 December 2020

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Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22875931