Cooperative epigenetic modulation by cancer amplicon genes (Q24608701)

21

0 references

Louis M Staudt

35

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Jan Delabie

29

0 references

Elaine Jaffe

Elaine S Jaffe

28

0 references

Elías Campo

Elias Campo

27

0 references

Erlend B. Smeland

30

Erlend B Smeland

0 references

David G. Maloney

18

Hans Konrad Müller-Hermelink

David Maloney

0 references

23

Hans Konrad Muller-Hermelink

0 references

Randy D Gascoyne

33

Randy D Gascoyne

0 references

Wing C Chan

32

Wing C Chan

0 references

Dennis D Weisenburger

31

Dennis D Weisenburger

0 references

Joseph M Connors

25

Joseph M Connors

0 references

Craig J. Thomas

Craig J Thomas

19

1 reference

ORCID Public Data File 2021

Lisa M Rimsza

26

Lisa M Rimsza

0 references

Arthur L Shaffer

10

Arthur L Shaffer

0 references

Kerry J Savage

24

Kerry Savage

0 references

Christian Steidl

5

Christian Steidl

0 references

Lixin Rui

1

Lixin Rui

0 references

Tolga Emre

2

N C Tolga Emre

0 references

Michael J Kruhlak

3

Michael J Kruhlak

0 references

Graham W Slack

6

Graham Slack

0 references

David Levens

34

David Levens

0 references

author name string

Hye-Jung Chung

4

0 references

George W Wright

7

0 references

Georg Lenz

8

0 references

Vu N Ngo

9

0 references

Weihong Xu

11

0 references

Hong Zhao

12

0 references

Yandan Yang

13

0 references

Laurence Lamy

14

0 references

R Eric Davis

15

0 references

Wenming Xiao

16

0 references

John Powell

17

0 references

Peter Möller

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin

20

0 references

language of work or name

English

0 references

publication date

14 December 2010

0 references

published in

Cancer Cell

0 references

volume

18

0 references

issue

6

0 references

page(s)

590-605

0 references

cites work

1 reference

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Janus kinases in immune cell signaling

7 April 2017

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Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

7 April 2017

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Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system

7 April 2017

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Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

7 April 2017

1 reference

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Global mapping of c-Myc binding sites and target gene networks in human B cells

7 April 2017

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Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

7 April 2017

1 reference

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In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation

7 April 2017

1 reference

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Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

7 April 2017

1 reference

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Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.

7 April 2017

1 reference

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

7 April 2017

1 reference

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

7 April 2017

1 reference

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Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

7 April 2017

1 reference

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Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

7 April 2017

1 reference

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The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

7 April 2017

1 reference

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Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components

7 April 2017

1 reference

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Kinetic analysis of the interleukin-13 receptor complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines

7 April 2017

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

7 April 2017

1 reference

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Rb targets histone H3 methylation and HP1 to promoters

7 April 2017

1 reference

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Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

No evidence for the JAK2 (V617F) or JAK2 exon 12 mutations in primary mediastinal large B-cell lymphoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

IRF4 addiction in multiple myeloma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

U-HO1, a new cell line derived from a primary refractory classical Hodgkin lymphoma

27 September 2017

1 reference

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The c-myc promoter: still MysterY and challenge

27 September 2017

1 reference

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Facultative heterochromatin: is there a distinctive molecular signature?

27 September 2017

1 reference

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JAK signaling globally counteracts heterochromatic gene silencing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

A library of gene expression signatures to illuminate normal and pathological lymphoid biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

A loss-of-function RNA interference screen for molecular targets in cancer

27 September 2017

1 reference

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Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Rituximab combined with MACOP-B or VACOP-B and radiation therapy in primary mediastinal large B-cell lymphoma: a retrospective study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic cells derived from myeloproliferative disorder patients with JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation negative patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049192

Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

28 November 2018

1 reference

12 December 2020

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene

1 reference

12 December 2020

Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

1 reference

12 December 2020

Absence of the JAK2 V617F activating mutation in classical Hodgkin lymphoma and primary mediastinal B-cell lymphoma

1 reference

12 December 2020

Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells

1 reference

12 December 2020

Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C

1 reference

12 December 2020

10.1016/J.CCR.2010.11.013

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

21156283

1 reference