The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition (Q24602026)

8

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David Cowburn

object named as

David Cowburn

7

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author name string

Juliya Kalinina

1

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Kaushik Dutta

2

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Dariush Ilghari

3

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Andrew Beenken

4

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Anna V Eliseenkova

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

6

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language of work or name

English

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publication date

11 January 2012

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published in

Structure

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volume

20

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issue

1

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page(s)

77-88

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cites work

1 reference

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Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain

7 April 2017

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Cellular signaling by fibroblast growth factor receptors

7 April 2017

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Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

7 April 2017

1 reference

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

7 April 2017

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Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors

7 April 2017

1 reference

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Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

7 April 2017

1 reference

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Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

7 April 2017

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Structural interactions of fibroblast growth factor receptor with its ligands

7 April 2017

1 reference

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Structural basis for FGF receptor dimerization and activation

7 April 2017

1 reference

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Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction

7 April 2017

1 reference

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Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants

7 April 2017

1 reference

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A crystallographic snapshot of tyrosine trans-phosphorylation in action

7 April 2017

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Structure of the extracellular region of HER3 reveals an interdomain tether

7 April 2017

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Using NMRView to visualize and analyze the NMR spectra of macromolecules

7 April 2017

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

7 April 2017

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

7 April 2017

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Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

7 April 2017

1 reference

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Structural and functional diversity in the FGF receptor multigene family

7 April 2017

1 reference

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Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

7 April 2017

1 reference

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Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors

7 April 2017

1 reference

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Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

7 April 2017

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Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer

27 September 2017

1 reference

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The FGF family: biology, pathophysiology and therapy

27 September 2017

1 reference

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Endocrine FGFs and Klothos: emerging concepts

27 September 2017

1 reference

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NMR structure of the first Ig module of mouse FGFR1

27 September 2017

1 reference

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A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

27 September 2017

1 reference

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Fibroblast growth factor homologous factors: evolution, structure, and function

27 September 2017

1 reference

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Structural basis for fibroblast growth factor receptor activation

27 September 2017

1 reference

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A novel alternatively spliced fibroblast growth factor receptor 3 isoform lacking the acid box domain is expressed during chondrogenic differentiation of ATDC5 cells

27 September 2017

1 reference

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Diversity does make a difference: fibroblast growth factor-heparin interactions

27 September 2017

1 reference

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Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas.

27 September 2017

1 reference

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Substitution of putative half-cystine residues in heparin-binding fibroblast growth factor receptors. Loss of binding activity in both two and three loop isoforms

27 September 2017

1 reference

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The extracellular domain of fibroblast growth factor receptor 3 inhibits ligand-independent dimerization

27 September 2017

1 reference

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Prostate cells express two isoforms of fibroblast growth factor receptor 1 with different affinities for fibroblast growth factor-2.

30 May 2018

1 reference

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Elucidation of the mechanism of the regulatory function of the Ig1 module of the fibroblast growth factor receptor 1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Internal dynamics control activation and activity of the autoinhibited Vav DH domain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Mutation, SNP, and isoform analysis of fibroblast growth factor receptor 3 (FGFR3) in 150 newly diagnosed multiple myeloma patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378326

Heparin-binding growth factor gene expression and receptor characteristics in normal rat prostate and two transplantable rat prostate tumors

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22244757

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural and Functional Diversity in the FGf Receptor Multigene Family

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.STR.2011.10.022