LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake (Q24598921)

2

0 references

Nathan K Karpowich

3

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Regina M Goetz

4

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Christopher J Law

5

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Maarten E A Reith

6

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Da-Neng Wang

Neurotransmitter transporters and their impact on the development of psychopharmacology

7

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language of work or name

English

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publication date

7 September 2007

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published in

Science

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volume

317

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issue

5843

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page(s)

1390-3

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cites work

1 reference

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Plasma membrane monoamine transporters: structure, regulation and function

24 March 2017

1 reference

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Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

24 March 2017

1 reference

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Drug discovery: a historical perspective

24 March 2017

1 reference

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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

24 March 2017

1 reference

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Cation-pi interactions in structural biology

7 April 2017

1 reference

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Identification of a chloride ion binding site in Na+/Cl -dependent transporters.

7 April 2017

1 reference

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Monitoring the function of membrane transport proteins in detergent-solubilized form

27 September 2017

1 reference

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Biogenic amine neurotransmitter transporters: just when you thought you knew them.

27 September 2017

1 reference

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Fate of tritiated noradrenaline at the sympathetic nerve-endings

27 September 2017

1 reference

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The antidepressant-sensitive dopamine transporter in Drosophila melanogaster: a primordial carrier for catecholamines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Families of transmembrane transporters selective for amino acids and their derivatives

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Problems with currently available antidepressants.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Serotonin, dopamine and norepinephrine transporters in the central nervous system and their inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

How do antidepressants work? Prospects for genetic analysis of drug mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type

27 September 2017

1 reference

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Neurotransmitter transporters: recent progress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Determination of residues in the norepinephrine transporter that are critical for tricyclic antidepressant affinity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

The serotonin transporter: a primary target for antidepressant drugs.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Determination of the dissociation constants (pKa) of secondary and tertiary amines in organic media by capillary electrophoresis and their role in the electrophoretic mobility order inversion

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

The family of Na+/Cl- neurotransmitter transporters.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

The Caenorhabditis elegans gene T23G5.5 encodes an antidepressant- and cocaine-sensitive dopamine transporter

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Reduced levels of norepinephrine transporters in the locus coeruleus in major depression.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3711652

Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17690258

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1147614

1 reference

1381880

1381880

1 reference

1 reference

1 reference